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    Research model

    Research models are used in medical research to mimic aspects of a disease or illness that occurs in humans. Research models can include animals (in vivo models), cell lines (in vitro models), or computer-driven demonstrations (in silico models). Research models allow doctors and scientists to uncover important information that can be applied to clinical practice.

    Webinars

    • OCT 06, 2021 | 12:00 AM
      Exploring Breast Cancer Health Disparities in African American Women
      Exploring Breast Cancer Health Disparities in African American...
      African American women face a lower risk of being diagnosed with breast cancer as compared to Caucasian-American women, yet they paradoxically face an increased breast cancer mortality hazar...
      Speaker: Checo J. Rorie, PhD
      Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
      1 1
      SEP 29, 2021 | 11:00 AM
      Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
      Automating culture and high-content imaging of 3D organoids for...
      Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
      Speaker: Oksana Sirenko, PhD
      Sponsored By: Molecular Devices
      9
      SEP 29, 2021 | 10:00 AM
      Study design: How and when to use multiplexed immunofluorescence imaging in your research
      Study design: How and when to use multiplexed immunofluorescence...
      Date: September 29, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions withi...
      Speaker: Melinda Angus-Hill Ph.D.
      Sponsored By: Leica Microsystems
      5
      SEP 22, 2021 | 11:59 PM
      Mechanisms of Podocyte Damage in Alport Syndrome: Insights from the Alport-on-a-chip System
      Mechanisms of Podocyte Damage in Alport Syndrome: Insights from...
      Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
      Speaker: Astgik Petrosyan, PhD
      Presented at: Cell Biology Virtual Event Series 2021
      0
      SEP 22, 2021 | 6:00 AM
      RNA Bead-Based Assays to Detect Tumour Gene Amplifications in Blood-Derived Exosomes
      RNA Bead-Based Assays to Detect Tumour Gene Amplifications in...
      Extracellular vesicles provide a tool to measure tumour characteristics in blood, at various stages of cancer development. We have extensively used multiplex RNA bead-based assays (Quantigen...
      Speaker: Godfrey Grech, PhD
      Presented at: Cell Biology Virtual Event Series 2021
      Sponsored By: Luminex - A DiaSorin Company
      2
      SEP 17, 2021 | 12:00 PM
      Developing better techniques for 3D culture and analysis.
      Developing better techniques for 3D culture and analysis.
      Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
      Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
      Sponsored By: Thermo Fisher Scientific/Gibco
      10 2
      SEP 14, 2021 | 7:00 AM
      What prevents you from increasing your PCR productivity?
      What prevents you from increasing your PCR productivity?
      Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
      Speaker: Arora Phang, PhD
      Sponsored By: Eppendorf
      24 1
      SEP 09, 2021 | 12:00 AM
      Log-linear Model for Modeling for Biases in Microbiome Studies
      Log-linear Model for Modeling for Biases in Microbiome Studies
      Microbiome sequencing data are known to be biased; the measured taxa relative abundances can be systematically distorted from their true values at every step in the experimental/analysis wor...
      Speaker: Ni Zhao, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      2
      SEP 08, 2021 | 10:30 AM
      A CRISPR-Powered Universal Infectious Disease Assay
      A CRISPR-Powered Universal Infectious Disease Assay
      Varicella zoster virus (VZV) causes two clinically distinct forms of disease, varicella and herpes zoster. These forms can each present with multiple manifestations ranging from lesions incl...
      Speaker: Jon Armstrong, MSc
      Presented at: Microbiology Week Virtual Event Series 2021
      Sponsored By: Jumpcode Genomics
      0
      SEP 08, 2021 | 9:00 AM
      Keynote Presentation: Development of an Affordable COVID-19 Vaccine Based on a Newcastle Disease Virus Platform
      Keynote Presentation: Development of an Affordable COVID-19 Vaccine...
      Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
      Speaker: Adolfo Garcia-Sastre, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 08, 2021 | 9:00 AM
      The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits, and humans
      The surface topography of silicone breast implants mediates the...
      Date: September 8, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Implanted biomedical devices comprise a major component of modern medicine and are essential for many clinical applications ranging...
      Speaker: Dr. Joshua Doloff
      Sponsored By: Thermo Fisher Scientific
      8
      SEP 08, 2021 | 12:00 AM
      SeXX Matters for Respiratory Viral Pathogenesis and Responses to Vaccines
      SeXX Matters for Respiratory Viral Pathogenesis and Responses...
      The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in COVID-...
      Speaker: Sabra L. Klein, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 08, 2021 | 12:00 AM
      Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
      Development of Self-Replicating Propagation-Defective RNAs as...
      Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
      Speaker: Isabel Sola, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 08, 2021 | 12:00 AM
      Translating Pharmacomicrobiomics: From Microbiome Cloud Uncertainty to Pharmaceutical and Clinical Application(s)
      Translating Pharmacomicrobiomics: From Microbiome Cloud Uncertainty...
      The Human Microbiome Project was conceived almost 15 years ago, as an extension of the Human Genome Project, to explore the diversity of human-associated microorganisms at multiple body site...
      Speaker: Ramy K. Aziz, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      1
      SEP 08, 2021 | 12:00 AM
      Machine Learning Approaches for Modeling Complex Community Dynamics
      Machine Learning Approaches for Modeling Complex Community Dynamics
      Computational or mathematical modeling generally refers to a mechanism-based formalism that help us test hypotheses, expand our understanding of a system, or make mechanism-aware predictions...
      Speaker: Nicholas Chia, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      SEP 07, 2021 | 9:00 AM
      Keynote Presentation: Mammalian RNAi Response to Virus Infection
      Keynote Presentation: Mammalian RNAi Response to Virus Infection
      Innate and adaptive immunity mechanisms provide antiviral protection in mammals. In this talk, I shall present recent findings from my lab and collaborators revealing a distinct form of mamm...
      Speaker: Shou-Wei Ding, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      1
      SEP 07, 2021 | 12:00 AM
      Plant Defense and Viral Counter-Defense Mechanisms Regulating Symptom Recovery, an Inducible Form of Plant Tolerance to Virus Infection
      Plant Defense and Viral Counter-Defense Mechanisms Regulating...
      Flaviviruses are pathogens of global public health concern. They include dengue virus (DENV), West Nile virus (WNV), and zika virus (ZIKV). There are no approved US Food and Drug Administrat...
      Speaker: Hélène Sanfaçon, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      4
      SEP 07, 2021 | 12:00 AM
      From Viral Infection to Neurodegeneration: The Role of Innate Immunity
      From Viral Infection to Neurodegeneration: The Role of Innate...
      Infection with human immunodeficiency virus (HIV)-1 compromises the immune system and causes in about half of the affected individuals neurological and neurocognitive complication categorize...
      Speaker: Marcus Kaul, PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      1
      SEP 07, 2021 | 12:00 AM
      Virus Replication:  The Role of the Unique Pathogenic Organelle
      Virus Replication: The Role of the Unique Pathogenic Organelle
      Nagy is a Professor in the Department of Plant Pathology, University of Kentucky. Dr. Nagy studies the functions of host proteins and lipids in viral RNA replication. The Nagy lab is using a...
      Speaker: Peter L. Nagy, MD., PhD
      Presented at: Microbiology Week Virtual Event Series 2021
      0
      AUG 31, 2021 | 9:00 AM
      The Regulation of ALC1 by TRIM33 during the DNA Damage Response
      The Regulation of ALC1 by TRIM33 during the DNA Damage Response
      Date: July 07, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA damage response is extremely crucial in maintaining genomic integrity. Failure to repair damaged DNA can result in the propagati...
      Speaker: Rukia Henry
      Sponsored By: Thermo Fisher Scientific/Gibco
      4
      AUG 25, 2021 | 1:30 PM
      Spatial Transcriptomics of Alzheimer's Disease Mouse Models with and Without Trem2R47H Mutation.
      Spatial Transcriptomics of Alzheimer's Disease Mouse Models with...
      In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
      Speaker: Frances Edwards, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: NanoString Technologies
      1
      AUG 25, 2021 | 12:00 PM
      Debate Discussion: Can We Generate an Organizing Theory of the Brain?
      Debate Discussion: Can We Generate an Organizing Theory of the...
      ...
      Speaker: David Kleinfeld, PhD , Mohammad M. Ghassemi, PhD , Florian Engert, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      2
      AUG 25, 2021 | 10:30 AM
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
      A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
      Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
      Speaker: Jason D. Hinman, PhD, MD
      Presented at: Neuroscience Virtual Event Series 2021
      Sponsored By: Luminex
      2
      AUG 25, 2021 | 9:00 AM
      Keynote Presentations: Current and Future Directions of the NIH BRAIN Initiative
      Keynote Presentations: Current and Future Directions of the NIH...
      The increasing burden of neurological disorders as our population ages, together with the high personal and societal costs of mental and substance use disorders, underscores the need for new...
      Speaker: John J. Ngai, PhD , Mohammad M. Ghassemi, PhD , Susan Wright, PhD , Grace Peng, PhD , Hsiao Yu (Christina) Fang, PhD , James Gnadt, PhD
      Presented at: Neuroscience Virtual Event Series 2021
      1
    OCT 06, 2021 | 12:00 AM
    Exploring Breast Cancer Health Disparities in African American Women
    Exploring Breast Cancer Health Disparities in African American...
    African American women face a lower risk of being diagnosed with breast cancer as compared to Caucasian-American women, yet they paradoxically face an increased breast cancer mortality hazar...
    Speaker: Checo J. Rorie, PhD
    Presented at: Cancer Research & Oncology Week Virtual Event Series 2021
    1 1
    SEP 29, 2021 | 11:00 AM
    Automating culture and high-content imaging of 3D organoids for in vitro assessment of compound effects
    Automating culture and high-content imaging of 3D organoids for...
    Date: Septembr 29, 2021 Time: 11:00am (PDT), 2:00pm (EDT) 3D cell models are becoming increasingly popular for studying complex biological effects, tissue functionality, and diseases. While...
    Speaker: Oksana Sirenko, PhD
    Sponsored By: Molecular Devices
    9
    SEP 29, 2021 | 10:00 AM
    Study design: How and when to use multiplexed immunofluorescence imaging in your research
    Study design: How and when to use multiplexed immunofluorescence...
    Date: September 29, 2021 Time: 10:00am (PDT), 1:00pm (EDT) Multiplexed tissue analysis is a powerful technique that allows comparisons of cell-type locations and cell-type interactions withi...
    Speaker: Melinda Angus-Hill Ph.D.
    Sponsored By: Leica Microsystems
    5
    SEP 22, 2021 | 11:59 PM
    Mechanisms of Podocyte Damage in Alport Syndrome: Insights from the Alport-on-a-chip System
    Mechanisms of Podocyte Damage in Alport Syndrome: Insights from...
    Microtubule plus-end tracking proteins (+TIPs) play key roles in the regulation of microtubule dynamics in vivo. These proteins bind to and regulate microtubule “plus‐ends”, whic...
    Speaker: Astgik Petrosyan, PhD
    Presented at: Cell Biology Virtual Event Series 2021
    0
    SEP 22, 2021 | 6:00 AM
    RNA Bead-Based Assays to Detect Tumour Gene Amplifications in Blood-Derived Exosomes
    RNA Bead-Based Assays to Detect Tumour Gene Amplifications in...
    Extracellular vesicles provide a tool to measure tumour characteristics in blood, at various stages of cancer development. We have extensively used multiplex RNA bead-based assays (Quantigen...
    Speaker: Godfrey Grech, PhD
    Presented at: Cell Biology Virtual Event Series 2021
    Sponsored By: Luminex - A DiaSorin Company
    2
     
     
  • SEP 17, 2021 | 12:00 PM
    Developing better techniques for 3D culture and analysis.
    Developing better techniques for 3D culture and analysis.
    Date: September 16, 2021 Time: 9:00pm (PDT), 12:00am (EDT) 3D cellular models like organoids and spheroids offer an opportunity to better understand complex biology in a physiologically rele...
    Speaker: Edwin Golez, M.S. , Bhaskar Mandavilli
    Sponsored By: Thermo Fisher Scientific/Gibco
    10 2
    SEP 14, 2021 | 7:00 AM
    What prevents you from increasing your PCR productivity?
    What prevents you from increasing your PCR productivity?
    Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
    Speaker: Arora Phang, PhD
    Sponsored By: Eppendorf
    24 1
    SEP 09, 2021 | 12:00 AM
    Log-linear Model for Modeling for Biases in Microbiome Studies
    Log-linear Model for Modeling for Biases in Microbiome Studies
    Microbiome sequencing data are known to be biased; the measured taxa relative abundances can be systematically distorted from their true values at every step in the experimental/analysis wor...
    Speaker: Ni Zhao, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    2
    SEP 08, 2021 | 10:30 AM
    A CRISPR-Powered Universal Infectious Disease Assay
    A CRISPR-Powered Universal Infectious Disease Assay
    Varicella zoster virus (VZV) causes two clinically distinct forms of disease, varicella and herpes zoster. These forms can each present with multiple manifestations ranging from lesions incl...
    Speaker: Jon Armstrong, MSc
    Presented at: Microbiology Week Virtual Event Series 2021
    Sponsored By: Jumpcode Genomics
    0
    SEP 08, 2021 | 9:00 AM
    Keynote Presentation: Development of an Affordable COVID-19 Vaccine Based on a Newcastle Disease Virus Platform
    Keynote Presentation: Development of an Affordable COVID-19 Vaccine...
    Highly efficacious vaccines against COVD-19 have been generated in a record time, and allowed a great impact in preventing severe disease due to SARS-CoV-2 infection in vaccinated individual...
    Speaker: Adolfo Garcia-Sastre, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
     
     
  • SEP 08, 2021 | 9:00 AM
    The surface topography of silicone breast implants mediates the foreign body response in mice, rabbits, and humans
    The surface topography of silicone breast implants mediates the...
    Date: September 8, 2021 Time: 9:00am (PDT), 12:00pm (EDT) Implanted biomedical devices comprise a major component of modern medicine and are essential for many clinical applications ranging...
    Speaker: Dr. Joshua Doloff
    Sponsored By: Thermo Fisher Scientific
    8
    SEP 08, 2021 | 12:00 AM
    SeXX Matters for Respiratory Viral Pathogenesis and Responses to Vaccines
    SeXX Matters for Respiratory Viral Pathogenesis and Responses...
    The ongoing COVID-19 pandemic has increased awareness about sex-specific differences in immunity and outcomes following respiratory virus infections. Strong evidence of a male bias in COVID-...
    Speaker: Sabra L. Klein, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    SEP 08, 2021 | 12:00 AM
    Development of Self-Replicating Propagation-Defective RNAs as Next Generation Vaccine Candidates Against Human Coronaviruses
    Development of Self-Replicating Propagation-Defective RNAs as...
    Self-amplifying RNA replicons are promising candidates for next generation vaccines against human coronaviruses with pandemic potential. Self-amplification of RNAs in host cells generates mo...
    Speaker: Isabel Sola, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    SEP 08, 2021 | 12:00 AM
    Translating Pharmacomicrobiomics: From Microbiome Cloud Uncertainty to Pharmaceutical and Clinical Application(s)
    Translating Pharmacomicrobiomics: From Microbiome Cloud Uncertainty...
    The Human Microbiome Project was conceived almost 15 years ago, as an extension of the Human Genome Project, to explore the diversity of human-associated microorganisms at multiple body site...
    Speaker: Ramy K. Aziz, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    1
    SEP 08, 2021 | 12:00 AM
    Machine Learning Approaches for Modeling Complex Community Dynamics
    Machine Learning Approaches for Modeling Complex Community Dynamics
    Computational or mathematical modeling generally refers to a mechanism-based formalism that help us test hypotheses, expand our understanding of a system, or make mechanism-aware predictions...
    Speaker: Nicholas Chia, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
     
     
  • SEP 07, 2021 | 9:00 AM
    Keynote Presentation: Mammalian RNAi Response to Virus Infection
    Keynote Presentation: Mammalian RNAi Response to Virus Infection
    Innate and adaptive immunity mechanisms provide antiviral protection in mammals. In this talk, I shall present recent findings from my lab and collaborators revealing a distinct form of mamm...
    Speaker: Shou-Wei Ding, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    1
    SEP 07, 2021 | 12:00 AM
    Plant Defense and Viral Counter-Defense Mechanisms Regulating Symptom Recovery, an Inducible Form of Plant Tolerance to Virus Infection
    Plant Defense and Viral Counter-Defense Mechanisms Regulating...
    Flaviviruses are pathogens of global public health concern. They include dengue virus (DENV), West Nile virus (WNV), and zika virus (ZIKV). There are no approved US Food and Drug Administrat...
    Speaker: Hélène Sanfaçon, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    4
    SEP 07, 2021 | 12:00 AM
    From Viral Infection to Neurodegeneration: The Role of Innate Immunity
    From Viral Infection to Neurodegeneration: The Role of Innate...
    Infection with human immunodeficiency virus (HIV)-1 compromises the immune system and causes in about half of the affected individuals neurological and neurocognitive complication categorize...
    Speaker: Marcus Kaul, PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    1
    SEP 07, 2021 | 12:00 AM
    Virus Replication:  The Role of the Unique Pathogenic Organelle
    Virus Replication: The Role of the Unique Pathogenic Organelle
    Nagy is a Professor in the Department of Plant Pathology, University of Kentucky. Dr. Nagy studies the functions of host proteins and lipids in viral RNA replication. The Nagy lab is using a...
    Speaker: Peter L. Nagy, MD., PhD
    Presented at: Microbiology Week Virtual Event Series 2021
    0
    AUG 31, 2021 | 9:00 AM
    The Regulation of ALC1 by TRIM33 during the DNA Damage Response
    The Regulation of ALC1 by TRIM33 during the DNA Damage Response
    Date: July 07, 2021 Time: 8:00am (PDT), 11:00am (EDT) The DNA damage response is extremely crucial in maintaining genomic integrity. Failure to repair damaged DNA can result in the propagati...
    Speaker: Rukia Henry
    Sponsored By: Thermo Fisher Scientific/Gibco
    4
     
     
  • AUG 25, 2021 | 1:30 PM
    Spatial Transcriptomics of Alzheimer's Disease Mouse Models with and Without Trem2R47H Mutation.
    Spatial Transcriptomics of Alzheimer's Disease Mouse Models with...
    In this preliminary experiment, we used spatial transcriptomics to assess the gene expression profiles of microglia or astrocytes in relation to their distance from plaques. We compared 18-m...
    Speaker: Frances Edwards, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: NanoString Technologies
    1
    AUG 25, 2021 | 12:00 PM
    Debate Discussion: Can We Generate an Organizing Theory of the Brain?
    Debate Discussion: Can We Generate an Organizing Theory of the...
    ...
    Speaker: David Kleinfeld, PhD , Mohammad M. Ghassemi, PhD , Florian Engert, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    2
    AUG 25, 2021 | 10:30 AM
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain Vascular Injury
    A Novel Blood-Based Biomarker for Silent Cerebral Edema and Brain...
    Emerging data from several expansive clinical trials indicates that common chronic vascular risk factors such as diabetes, hypertension, obesity, and age increase the risk of stroke and deme...
    Speaker: Jason D. Hinman, PhD, MD
    Presented at: Neuroscience Virtual Event Series 2021
    Sponsored By: Luminex
    2
    AUG 25, 2021 | 9:00 AM
    Keynote Presentations: Current and Future Directions of the NIH BRAIN Initiative
    Keynote Presentations: Current and Future Directions of the NIH...
    The increasing burden of neurological disorders as our population ages, together with the high personal and societal costs of mental and substance use disorders, underscores the need for new...
    Speaker: John J. Ngai, PhD , Mohammad M. Ghassemi, PhD , Susan Wright, PhD , Grace Peng, PhD , Hsiao Yu (Christina) Fang, PhD , James Gnadt, PhD
    Presented at: Neuroscience Virtual Event Series 2021
    1
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