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    CAR-T cell therapy

    Chimeric antigen receptor (CAR) T cell therapy is a form of T cell engineering where T cells are obtained from a patient and engineered in a laboratory to better kill the patient's cancer cells. Specifically, CAR T cells are modified to express a receptor on their surface that recognizes the specific antigen present on the patient's cancer cells.

    Trending News

    • SEP 23, 2022
      Immunology
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      Successful Immunotherapy Trial Sends Lupus Into Remission
      Immunotherapy is generally known as a treatment for cancer. In CAR T cell therapy, a patient's T cells can be isolat ...
      Written By: Carmen Leitch
      1
      JUL 11, 2022
      Cancer
      Boosting CAR T Cell Therapy with TIGIT Blockade
      Boosting CAR T Cell Therapy with TIGIT Blockade
      Chimeric antigen receptor (CAR) T Cell therapy has emerged as a promising immunotherapeutic approach to treat blood canc ...
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      JUN 30, 2022
      Cancer
      Differences between Hodgkin and non-Hodgkin Lymphoma
      Differences between Hodgkin and non-Hodgkin Lymphoma
      Lymphoma, broadly, describes a type of cancer that develops in the lymph system, a complex network made up of organs, no ...
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      FEB 06, 2022
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      Researchers use CRISPR Technology to Study How Immune Cells Work
      Researchers use CRISPR Technology to Study How Immune Cells Work
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      JAN 27, 2022
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      OCT 22, 2021
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      Studying the Evolution of SARS-CoV-2 in One Patient Over 324 Days
      To clear a viral infection, the human body has to mount an effective immune response. After detecting the pathogen, immu ...
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      OCT 18, 2021
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      OCT 07, 2021
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      SEP 16, 2021
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      AUG 30, 2021
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      AUG 15, 2021
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      MAY 31, 2021
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      MAR 18, 2021
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      JAN 28, 2021
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      JAN 04, 2021
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      DEC 27, 2020
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      NOV 29, 2020
      Cell & Molecular Biology
      Engineering 'Smart' Cells to Kill Cancer
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      Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
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      SEP 07, 2020
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      CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
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      JUN 09, 2020
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      Peacekeeping Engineered T Cells Restore the Balance in Diabetes
      Peacekeeping Engineered T Cells Restore the Balance in Diabetes
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      JUN 07, 2020
      Cancer
      T cell metabolism in old age
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      MAY 10, 2020
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      Towards a Targeted Elimination of Leukemic Cells
      Towards a Targeted Elimination of Leukemic Cells
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      APR 22, 2020
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    SEP 23, 2022
    Immunology
    Successful Immunotherapy Trial Sends Lupus Into Remission
    Successful Immunotherapy Trial Sends Lupus Into Remission
    Immunotherapy is generally known as a treatment for cancer. In CAR T cell therapy, a patient's T cells can be isolat ...
    Written By: Carmen Leitch
    1
    JUL 11, 2022
    Cancer
    Boosting CAR T Cell Therapy with TIGIT Blockade
    Boosting CAR T Cell Therapy with TIGIT Blockade
    Chimeric antigen receptor (CAR) T Cell therapy has emerged as a promising immunotherapeutic approach to treat blood canc ...
    Written By: Katie Kokolus
    4
    JUN 30, 2022
    Cancer
    Differences between Hodgkin and non-Hodgkin Lymphoma
    Differences between Hodgkin and non-Hodgkin Lymphoma
    Lymphoma, broadly, describes a type of cancer that develops in the lymph system, a complex network made up of organs, no ...
    Written By: Katie Kokolus
    6
    FEB 06, 2022
    Technology
    Researchers use CRISPR Technology to Study How Immune Cells Work
    Researchers use CRISPR Technology to Study How Immune Cells Work
    The immune system is one of the most complex aspects of human biology. In addition to protecting our body from bacterial ...
    Written By: Ryan Vingum
    2
    JAN 27, 2022
    Cancer
    Can Magnesium Help the Immune System Fight Cancer?
    Can Magnesium Help the Immune System Fight Cancer?
    Magnesium deficiency is associated with some types of cancer, including breast, ovarian, and kidney cancer.  Pre-cl ...
    Written By: Katie Kokolus
    4
     
     
  • OCT 22, 2021
    Genetics & Genomics
    Studying the Evolution of SARS-CoV-2 in One Patient Over 324 Days
    Studying the Evolution of SARS-CoV-2 in One Patient Over 324 Days
    To clear a viral infection, the human body has to mount an effective immune response. After detecting the pathogen, immu ...
    Written By: Carmen Leitch
    1
    OCT 18, 2021
    Cancer
    The History of Immunotherapy: Toxins, Targets & T Cells
    The History of Immunotherapy: Toxins, Targets & T Cells
    Cancer immunotherapy, a treatment that directly enhances a patient’s immune system, is typically perceived as a mo ...
    Written By: Katie Kokolus
    3
    OCT 07, 2021
    Cancer
    Dual Threat: CAR T Cells Modified to Target Two Neuroblastoma Antigens
    Dual Threat: CAR T Cells Modified to Target Two Neuroblastoma Antigens
    Neuroblastoma is a cancer of immature nerve cells found in various areas, including the adrenal glands, neck, chest ...
    Written By: Katie Kokolus
    4
    SEP 16, 2021
    Cancer
    Inspiring Hope during Childhood Cancer Awareness Month
    Inspiring Hope during Childhood Cancer Awareness Month
    Childhood cancers, also known as pediatric cancers, are diagnosed in patients up to 14 years old.  Estimates for 20 ...
    Written By: Katie Kokolus
    3
    AUG 30, 2021
    Cancer
    A Hot Approach to CAR T Cells
    A Hot Approach to CAR T Cells
    Immunotherapy, a type of treatment that targets a patient’s immune system to enhance the natural ability to attack ...
    Written By: Katie Kokolus
    3
     
     
  • AUG 15, 2021
    Health & Medicine
    A COVID-19 Vaccine Booster Now Recommended for Immunocompromised People
    A COVID-19 Vaccine Booster Now Recommended for Immunocompromised People
    As Delta has become the dominant SARS-CoV-2 variant causing COVID-19 infections in the United States, researchers and he ...
    Written By: Carmen Leitch
    1
    AUG 13, 2021
    Cancer
    Ultrasound Triggers Immunotherapy to Destroy Tumors
    Ultrasound Triggers Immunotherapy to Destroy Tumors
    An immunotherapy engineered to be triggered by ultrasound beams significantly slows the growth of cancerous tumors in mi ...
    Written By: Annie Lennon
    1
    JUL 12, 2021
    Cell & Molecular Biology
    A Molecule From the Gut Microbiome May Fight Tumors
    A Molecule From the Gut Microbiome May Fight Tumors
    The more we learn abut the gut microbiome, the more it seems that the microorganisms in our gastrointestinal tracts can ...
    Written By: Carmen Leitch
    3
    MAY 31, 2021
    Immunology
    Engineering Faster, More Agile T Cell Cancer Fighters
    Engineering Faster, More Agile T Cell Cancer Fighters
    Cell therapies use engineered T cells extracted from the patient’s own immune system to rally an attack on tumors. ...
    Written By: Tara Fernandes
    1
    MAR 18, 2021
    Drug Discovery & Development
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
    Written By: Annie Lennon
    1
     
     
  • JAN 28, 2021
    Immunology
    Killers With a Hit on the Spike
    Killers With a Hit on the Spike
    Natural killer cells, or NK cells, are specialized immune cells of the innate immune system. Their job revolves around e ...
    Written By: Tara Fernandes
    1
    JAN 04, 2021
    Cell & Molecular Biology
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Researchers have reported positive results from a phase 2 clinical trial of a CAR T cell therapy called axicabtagene cil ...
    Written By: Carmen Leitch
    1
    DEC 27, 2020
    Immunology
    A Fatty Diet can be Fuel for Tumor Growth!
    A Fatty Diet can be Fuel for Tumor Growth!
    Obesity is a significant problem in our societies with increasing the risk for many diseases, including cancer. Can ...
    Written By: Heba El-wassef
    1
    NOV 29, 2020
    Cell & Molecular Biology
    Engineering 'Smart' Cells to Kill Cancer
    Engineering 'Smart' Cells to Kill Cancer
    Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
    Written By: Carmen Leitch
    1
    SEP 07, 2020
    Immunology
    CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
    CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
    The ability to edit the human genome using CRISPR has been heralded as a revolution in medicine. However, one of the big ...
    Written By: Tara Fernandes
    1
     
     
  • JUN 09, 2020
    Immunology
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    For patients with type 1 diabetes, hope is around the corner with a new experimental therapy that uses genetically modif ...
    Written By: Tara Fernandes
    1
    JUN 07, 2020
    Cancer
    T cell metabolism in old age
    T cell metabolism in old age
    New research published in Nature Communications suggests that the increased metabolism of T cells that we see with advan ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 10, 2020
    Genetics & Genomics
    Towards a Targeted Elimination of Leukemic Cells
    Towards a Targeted Elimination of Leukemic Cells
    Our blood carries many types of critical cells, including platelets, red blood cells, and white blood cells, which are m ...
    Written By: Carmen Leitch
    2
    APR 22, 2020
    Immunology
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    The best offense may be a good defense in the fight against COVID-19. Researchers from the Duke-NUS Medical School are e ...
    Written By: Kara Marker
    1
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