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    CAR-T cell therapy

    Chimeric antigen receptor (CAR) T cell therapy is a form of T cell engineering where T cells are obtained from a patient and engineered in a laboratory to better kill the patient's cancer cells. Specifically, CAR T cells are modified to express a receptor on their surface that recognizes the specific antigen present on the patient's cancer cells.

    Trending News

    • AUG 13, 2021
      Cancer
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      Ultrasound Triggers Immunotherapy to Destroy Tumors
      An immunotherapy engineered to be triggered by ultrasound beams significantly slows the growth of cancerous tumors in mi ...
      Written By: Annie Lennon
      1
      JUL 12, 2021
      Cell & Molecular Biology
      A Molecule From the Gut Microbiome May Fight Tumors
      A Molecule From the Gut Microbiome May Fight Tumors
      The more we learn abut the gut microbiome, the more it seems that the microorganisms in our gastrointestinal tracts can ...
      Written By: Carmen Leitch
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      MAY 31, 2021
      Immunology
      Engineering Faster, More Agile T Cell Cancer Fighters
      Engineering Faster, More Agile T Cell Cancer Fighters
      Cell therapies use engineered T cells extracted from the patient’s own immune system to rally an attack on tumors. ...
      Written By: Tara Fernandes
      1
      MAR 18, 2021
      Drug Discovery & Development
      New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
      New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
      Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
      Written By: Annie Lennon
      1
      JAN 28, 2021
      Immunology
      Killers With a Hit on the Spike
      Killers With a Hit on the Spike
      Natural killer cells, or NK cells, are specialized immune cells of the innate immune system. Their job revolves around e ...
      Written By: Tara Fernandes
      1
      JAN 04, 2021
      Cell & Molecular Biology
      Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
      Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
      Researchers have reported positive results from a phase 2 clinical trial of a CAR T cell therapy called axicabtagene cil ...
      Written By: Carmen Leitch
      1
      DEC 27, 2020
      Immunology
      A Fatty Diet can be Fuel for Tumor Growth!
      A Fatty Diet can be Fuel for Tumor Growth!
      Obesity is a significant problem in our societies with increasing the risk for many diseases, including cancer. Can ...
      Written By: Heba El-wassef
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      NOV 29, 2020
      Cell & Molecular Biology
      Engineering 'Smart' Cells to Kill Cancer
      Engineering 'Smart' Cells to Kill Cancer
      Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
      Written By: Carmen Leitch
      1
      SEP 07, 2020
      Immunology
      CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
      CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
      The ability to edit the human genome using CRISPR has been heralded as a revolution in medicine. However, one of the big ...
      Written By: Tara Fernandes
      1
      JUN 09, 2020
      Immunology
      Peacekeeping Engineered T Cells Restore the Balance in Diabetes
      Peacekeeping Engineered T Cells Restore the Balance in Diabetes
      For patients with type 1 diabetes, hope is around the corner with a new experimental therapy that uses genetically modif ...
      Written By: Tara Fernandes
      1
      JUN 07, 2020
      Cancer
      T cell metabolism in old age
      T cell metabolism in old age
      New research published in Nature Communications suggests that the increased metabolism of T cells that we see with advan ...
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      MAY 10, 2020
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      Towards a Targeted Elimination of Leukemic Cells
      Towards a Targeted Elimination of Leukemic Cells
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      2
      APR 22, 2020
      Immunology
      Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
      Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
      The best offense may be a good defense in the fight against COVID-19. Researchers from the Duke-NUS Medical School are e ...
      Written By: Kara Marker
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      APR 13, 2020
      Cancer
      The Unexpected Role of Mono in Cancer Progression
      The Unexpected Role of Mono in Cancer Progression
      In the past, the go-to drugs have always been small molecules. These small molecules would interact with the cell and ac ...
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      APR 11, 2020
      Cancer
      The Mice Make the Difference in CAR-T Studies
      The Mice Make the Difference in CAR-T Studies
      It is quite common in cancer therapies to see a drug or treatment that has been around for decades. New drugs are hard t ...
      Written By: Jasper Cantrell
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      FEB 14, 2020
      Immunology
      Rewired natural killer cells show promising results in leukemia patients
      Rewired natural killer cells show promising results in leukemia patients
      Natural killer (NK) cells are a subset of white blood cells that are key players in the innate immune system, orchestrat ...
      Written By: Tara Fernandes
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      FEB 02, 2020
      Cell & Molecular Biology
      New T Cell Therapy is a Universal Approach to Target Cancer
      New T Cell Therapy is a Universal Approach to Target Cancer
      For years, researchers have been trying to harness the power of the assassins of the immune system - killer T cells.
      Written By: Carmen Leitch
      2 1
      JAN 24, 2020
      Immunology
      Immune "Recycling" Could Improve Cancer Immunotherapy
      Immune "Recycling" Could Improve Cancer Immunotherapy
      A natural housekeeping function performed by many cells of the human body, including those in the immune system, is unde ...
      Written By: Kara Marker
      1
      DEC 15, 2019
      Genetics & Genomics
      Making T-Cell Therapy Even More Effective
      Making T-Cell Therapy Even More Effective
      Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
      Written By: Carmen Leitch
      1
      OCT 13, 2019
      Cell & Molecular Biology
      Differences in Pediatric vs. Adult Cancer Force the Discussion of Effective Therapies
      Differences in Pediatric vs. Adult Cancer Force the Discussion of Effective Therapies
      A team of scientists study the differences between childhood and adult cancer. This drives the discussion of the use of ...
      Written By: Carly Boyd
      1
      OCT 08, 2019
      Cell & Molecular Biology
      New Type of CAR T-Cell Therapy Headed for Clinical Trials
      New Type of CAR T-Cell Therapy Headed for Clinical Trials
      Scientists have been trying to use the immune system in cancer patients' bodies to fight cancer.
      Written By: Carmen Leitch
      1
      AUG 29, 2019
      Cell & Molecular Biology
      Dysfunctional Mitochondria Cause Telomere Damage
      Dysfunctional Mitochondria Cause Telomere Damage
      "I like to call it 'the Chernobyl effect' -- you've turned the reactor on and now you can't turn it off," said senior au ...
      Written By: Carmen Leitch
      1
      APR 18, 2019
      Immunology
      The C-word. Michael Kinch's new book and the future of Cancer Treatment
      The C-word. Michael Kinch's new book and the future of Cancer Treatment
      The C-word. Dare we say it? Is a cure for cancer within reach?   Professor Michael Kinch https://publichealth.wustl ...
      Written By: Aleishia Harris-Arnold
      2
      MAR 30, 2019
      Videos
      A Primer on Cell Therapy, Gene Therapy & Gene Editing
      A Primer on Cell Therapy, Gene Therapy & Gene Editing
      There are many diseases that can be traced back to errors in genes. Gene therapy aims to fix those errors.
      Written By: Carmen Leitch
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    AUG 13, 2021
    Cancer
    Ultrasound Triggers Immunotherapy to Destroy Tumors
    Ultrasound Triggers Immunotherapy to Destroy Tumors
    An immunotherapy engineered to be triggered by ultrasound beams significantly slows the growth of cancerous tumors in mi ...
    Written By: Annie Lennon
    1
    JUL 12, 2021
    Cell & Molecular Biology
    A Molecule From the Gut Microbiome May Fight Tumors
    A Molecule From the Gut Microbiome May Fight Tumors
    The more we learn abut the gut microbiome, the more it seems that the microorganisms in our gastrointestinal tracts can ...
    Written By: Carmen Leitch
    3
    MAY 31, 2021
    Immunology
    Engineering Faster, More Agile T Cell Cancer Fighters
    Engineering Faster, More Agile T Cell Cancer Fighters
    Cell therapies use engineered T cells extracted from the patient’s own immune system to rally an attack on tumors. ...
    Written By: Tara Fernandes
    1
    MAR 18, 2021
    Drug Discovery & Development
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
    Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
    Written By: Annie Lennon
    1
    JAN 28, 2021
    Immunology
    Killers With a Hit on the Spike
    Killers With a Hit on the Spike
    Natural killer cells, or NK cells, are specialized immune cells of the innate immune system. Their job revolves around e ...
    Written By: Tara Fernandes
    1
     
     
  • JAN 04, 2021
    Cell & Molecular Biology
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Good Results From Trial of CAR T Cell Therapy for Non-Hodgkin Lymphoma
    Researchers have reported positive results from a phase 2 clinical trial of a CAR T cell therapy called axicabtagene cil ...
    Written By: Carmen Leitch
    1
    DEC 27, 2020
    Immunology
    A Fatty Diet can be Fuel for Tumor Growth!
    A Fatty Diet can be Fuel for Tumor Growth!
    Obesity is a significant problem in our societies with increasing the risk for many diseases, including cancer. Can ...
    Written By: Heba El-wassef
    1
    NOV 29, 2020
    Cell & Molecular Biology
    Engineering 'Smart' Cells to Kill Cancer
    Engineering 'Smart' Cells to Kill Cancer
    Cancer researchers have long been searching for a way to target cancer cells while ignoring healthy cells. A team of sci ...
    Written By: Carmen Leitch
    1
    SEP 07, 2020
    Immunology
    CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
    CRISPR Pumps the Brakes on the Immune System to Support Gene Therapies
    The ability to edit the human genome using CRISPR has been heralded as a revolution in medicine. However, one of the big ...
    Written By: Tara Fernandes
    1
    JUN 09, 2020
    Immunology
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    Peacekeeping Engineered T Cells Restore the Balance in Diabetes
    For patients with type 1 diabetes, hope is around the corner with a new experimental therapy that uses genetically modif ...
    Written By: Tara Fernandes
    1
     
     
  • JUN 07, 2020
    Cancer
    T cell metabolism in old age
    T cell metabolism in old age
    New research published in Nature Communications suggests that the increased metabolism of T cells that we see with advan ...
    Written By: Kathryn DeMuth Sullivan
    2
    MAY 10, 2020
    Genetics & Genomics
    Towards a Targeted Elimination of Leukemic Cells
    Towards a Targeted Elimination of Leukemic Cells
    Our blood carries many types of critical cells, including platelets, red blood cells, and white blood cells, which are m ...
    Written By: Carmen Leitch
    2
    APR 22, 2020
    Immunology
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    Scientists Engineer Custom Antiviral Receptors to Fight COVID-19
    The best offense may be a good defense in the fight against COVID-19. Researchers from the Duke-NUS Medical School are e ...
    Written By: Kara Marker
    1
    APR 13, 2020
    Cancer
    The Unexpected Role of Mono in Cancer Progression
    The Unexpected Role of Mono in Cancer Progression
    In the past, the go-to drugs have always been small molecules. These small molecules would interact with the cell and ac ...
    Written By: Jasper Cantrell
    1
    APR 11, 2020
    Cancer
    The Mice Make the Difference in CAR-T Studies
    The Mice Make the Difference in CAR-T Studies
    It is quite common in cancer therapies to see a drug or treatment that has been around for decades. New drugs are hard t ...
    Written By: Jasper Cantrell
    1
     
     
  • FEB 14, 2020
    Immunology
    Rewired natural killer cells show promising results in leukemia patients
    Rewired natural killer cells show promising results in leukemia patients
    Natural killer (NK) cells are a subset of white blood cells that are key players in the innate immune system, orchestrat ...
    Written By: Tara Fernandes
    1
    FEB 02, 2020
    Cell & Molecular Biology
    New T Cell Therapy is a Universal Approach to Target Cancer
    New T Cell Therapy is a Universal Approach to Target Cancer
    For years, researchers have been trying to harness the power of the assassins of the immune system - killer T cells.
    Written By: Carmen Leitch
    2 1
    JAN 24, 2020
    Immunology
    Immune "Recycling" Could Improve Cancer Immunotherapy
    Immune "Recycling" Could Improve Cancer Immunotherapy
    A natural housekeeping function performed by many cells of the human body, including those in the immune system, is unde ...
    Written By: Kara Marker
    1
    DEC 15, 2019
    Genetics & Genomics
    Making T-Cell Therapy Even More Effective
    Making T-Cell Therapy Even More Effective
    Curated w/video - CRISPR/Cas9 deletion of an enzyme resulted in longer lasting, more robust therapy.
    Written By: Carmen Leitch
    1
    OCT 13, 2019
    Cell & Molecular Biology
    Differences in Pediatric vs. Adult Cancer Force the Discussion of Effective Therapies
    Differences in Pediatric vs. Adult Cancer Force the Discussion of Effective Therapies
    A team of scientists study the differences between childhood and adult cancer. This drives the discussion of the use of ...
    Written By: Carly Boyd
    1
     
     
  • OCT 08, 2019
    Cell & Molecular Biology
    New Type of CAR T-Cell Therapy Headed for Clinical Trials
    New Type of CAR T-Cell Therapy Headed for Clinical Trials
    Scientists have been trying to use the immune system in cancer patients' bodies to fight cancer.
    Written By: Carmen Leitch
    1
    AUG 29, 2019
    Cell & Molecular Biology
    Dysfunctional Mitochondria Cause Telomere Damage
    Dysfunctional Mitochondria Cause Telomere Damage
    "I like to call it 'the Chernobyl effect' -- you've turned the reactor on and now you can't turn it off," said senior au ...
    Written By: Carmen Leitch
    1
    APR 18, 2019
    Immunology
    The C-word. Michael Kinch's new book and the future of Cancer Treatment
    The C-word. Michael Kinch's new book and the future of Cancer Treatment
    The C-word. Dare we say it? Is a cure for cancer within reach?   Professor Michael Kinch https://publichealth.wustl ...
    Written By: Aleishia Harris-Arnold
    2
    MAR 30, 2019
    Videos
    A Primer on Cell Therapy, Gene Therapy & Gene Editing
    A Primer on Cell Therapy, Gene Therapy & Gene Editing
    There are many diseases that can be traced back to errors in genes. Gene therapy aims to fix those errors.
    Written By: Carmen Leitch
    2
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