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    Motor Neurone Disease

    Motor neurone (or neuron) disease (MND), also called amyotrophic lateral sclerosis (ALS) or Lou Gehrig's disease, is a rare, degenerative condition impacting the brain and nerves. Patients with MND often experience muscle weakness which becomes greater and more debilitating over time. While there is no cure for this disease, many of the symptoms can be managed to improve quality of life.

    Trending News

    • JAN 01, 2025
      Genetics & Genomics
      A Cellular Defect That May Help Explain ALS is Revealed
      A Cellular Defect That May Help Explain ALS is Revealed
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      Written By: Carmen Leitch
      2
      NOV 18, 2023
      Neuroscience
      Inhibiting Enzyme Shows Promise in Halting Parkinson's
      Inhibiting Enzyme Shows Promise in Halting Parkinson's
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      OCT 06, 2023
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      SEP 25, 2023
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      SEP 06, 2023
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      AUG 18, 2023
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      JUN 08, 2023
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      APR 20, 2023
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      Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
      Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
      This work has also highlighted the importance of assessing a diverse group of patients when studying a disease.
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      APR 02, 2023
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      MAR 31, 2023
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      MAR 23, 2023
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      A Cause of Neurodegeneration in ALS & Potentially Other Diseases is Revealed
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      FEB 07, 2023
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      ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
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      JAN 17, 2023
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      DEC 24, 2022
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      NOV 10, 2022
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      OCT 04, 2022
      Clinical & Molecular DX
      The Human Brain Project is Changing What We Know About Lou Gehrig's Disease
      The Human Brain Project is Changing What We Know About Lou Gehrig's Disease
      Amyotrophic Lateral Sclerosis (ALS) is a progressive neuromuscular disease in which the motor nerve cells in the brain a ...
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      OCT 04, 2022
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      New Insights Into How Breaks in 'Junk' DNA are Repaired
      New Insights Into How Breaks in 'Junk' DNA are Repaired
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      AUG 16, 2022
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      Blood Pressure Drug Shows Promise for Treating ALS
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      AUG 16, 2022
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      A Common Denominator Among All Forms of ALS is Revealed
      A Common Denominator Among All Forms of ALS is Revealed
      ALS (amyotrophic lateral sclerosis) is a motor neuron disease, which gradually causes a loss of movement. Eventually, pa ...
      Written By: Carmen Leitch
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      JUL 18, 2022
      Neuroscience
      Researchers See the Formation of Motor Memories in Mice
      Researchers See the Formation of Motor Memories in Mice
      People usually only have to learn how to ride a bicycle once; and once a person learns how, they can get on and start ri ...
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      MAY 25, 2022
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      MAY 19, 2022
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      Experimental Drug Shows Promise Against ALS
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    JAN 01, 2025
    Genetics & Genomics
    A Cellular Defect That May Help Explain ALS is Revealed
    A Cellular Defect That May Help Explain ALS is Revealed
    Amyotrophic lateral sclerosis (ALS) is a serious and usually fatal neurodegenerative disorder in which motor neurons det ...
    Written By: Carmen Leitch
    2
    NOV 18, 2023
    Neuroscience
    Inhibiting Enzyme Shows Promise in Halting Parkinson's
    Inhibiting Enzyme Shows Promise in Halting Parkinson's
    Inhibiting an enzyme called USP30 in mice protects dopamine-producing neurons, which are typically lost as Parkinson' ...
    Written By: Annie Lennon
    3
    OCT 06, 2023
    Technology
    Novel imaging to study Parkinson's disease progression
    Novel imaging to study Parkinson's disease progression
    A team of researchers at the Ecole Polytechnique Fédérale de Lausanne are leveraging leading-edge imaging ...
    Written By: Ryan Vingum
    4
    SEP 25, 2023
    Cell & Molecular Biology
    After Neuronal Damage, Researchers Restore Walking in Mice
    After Neuronal Damage, Researchers Restore Walking in Mice
    If the spinal cord in a mouse or human suffers damage, temporary paralysis occurs until the damage is healed, and motor ...
    Written By: Carmen Leitch
    5
    SEP 06, 2023
    Neuroscience
    Newly Discovered Brain Cell Type Has Extensive Abilities
    Newly Discovered Brain Cell Type Has Extensive Abilities
    A groundbreaking Nature paper unveils the glutamatergic astrocytes, a novel brain cell with dual functionality and offer ...
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    6
     
     
  • AUG 18, 2023
    Genetics & Genomics
    'Ice Bucket Challenge' Gene Research Opens New Insights Into ALS Causes, Treatment
    'Ice Bucket Challenge' Gene Research Opens New Insights Into ALS Causes, Treatment
    Since 2014, the ALS Ice Bucket Challenge https://www.als.org/IBC has inspired more than 17 million people to raise $115 ...
    Written By: Carmen Leitch
    4
    JUN 08, 2023
    Genetics & Genomics
    An Ancient Viral Remnant May Underlie ALS
    An Ancient Viral Remnant May Underlie ALS
    The human genome contains many sequences that came from ancient viruses. It's been thought that most of these regions ar ...
    Written By: Carmen Leitch
    4
    APR 20, 2023
    Health & Medicine
    New Insights Into How Exercise Improves Brain Health
    New Insights Into How Exercise Improves Brain Health
    Along with a good diet, physical activity is known as a way to maintain or boost health, especially cardiovascular healt ...
    Written By: Carmen Leitch
    2
    APR 16, 2023
    Cell & Molecular Biology
    Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
    Revealing the Impact of Drastic RNA Editing Changes in Schizophrenia
    This work has also highlighted the importance of assessing a diverse group of patients when studying a disease.
    Written By: Carmen Leitch
    3
    APR 02, 2023
    Genetics & Genomics
    Advances in Spinal Muscular Atrophy Present Potential Treatment Options
    Advances in Spinal Muscular Atrophy Present Potential Treatment Options
    SMA is a leading cause of infant mortality. Most cases of the disease are caused by mutations in a gene called SMN1 that ...
    Written By: Carmen Leitch
    2
     
     
  • MAR 31, 2023
    Genetics & Genomics
    Amino Acids Have a Significant Influence on Neuronal Development
    Amino Acids Have a Significant Influence on Neuronal Development
    The development of the brain has been studied in detail in various organisms, and we know a lot about the genes and cell ...
    Written By: Carmen Leitch
    5
    MAR 28, 2023
    Drug Discovery & Development
    FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
    FDA's advisory panel recommends approval for an "ultra-rare" ALS drug
    Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease that is also known as Lou Gehrig’s Disease. It ...
    Written By: Greta Anne
    4
    MAR 23, 2023
    Neuroscience
    A Cause of Neurodegeneration in ALS & Potentially Other Diseases is Revealed
    A Cause of Neurodegeneration in ALS & Potentially Other Diseases is Revealed
    Amyotrophic lateral sclerosis (ALS), is a fatal disease in which motor neurons degenerate, causing a gradual but total l ...
    Written By: Carmen Leitch
    3
    FEB 07, 2023
    Health & Medicine
    ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
    ALS Breakthrough: Two Targets Touted to Treat TDP-43 Trafficking Trouble
    One lab drops two papers touting the clearance of protein aggregation in ALS
    Written By: Amielle Moreno
    2
    JAN 17, 2023
    Health & Medicine
    Stem Cell-Derived Neurons Reaching Maturity Thanks to Dynamic Nanofibers
    Stem Cell-Derived Neurons Reaching Maturity Thanks to Dynamic Nanofibers
    Northwestern University scientists developed a new culturing technology with synthetic nanofibers and therapeutic peptid ...
    Written By: Amielle Moreno
    3
     
     
  • DEC 24, 2022
    Neuroscience
    A Probiotic Microbe Could Protect Against ALS
    A Probiotic Microbe Could Protect Against ALS
    The microbes in our guts are closely connected to our brains, in a link known as the gut-brain axis. Scientists have now ...
    Written By: Carmen Leitch
    1
    NOV 10, 2022
    Neuroscience
    HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
    HUSH - A Complex That Silences Genes & Helps Control Brain Architecture
    The HUSH (human silencing hub) protein complex is known to silence genes, and researchers have thought that it could be ...
    Written By: Carmen Leitch
    1
    OCT 04, 2022
    Clinical & Molecular DX
    The Human Brain Project is Changing What We Know About Lou Gehrig's Disease
    The Human Brain Project is Changing What We Know About Lou Gehrig's Disease
    Amyotrophic Lateral Sclerosis (ALS) is a progressive neuromuscular disease in which the motor nerve cells in the brain a ...
    Written By: Zoe Michaud
    2
    OCT 04, 2022
    Genetics & Genomics
    New Insights Into How Breaks in 'Junk' DNA are Repaired
    New Insights Into How Breaks in 'Junk' DNA are Repaired
    For many years researchers focused attention on protein-coding genes, and while they are very important, they only accou ...
    Written By: Carmen Leitch
    1
    AUG 16, 2022
    Drug Discovery & Development
    Blood Pressure Drug Shows Promise for Treating ALS
    Blood Pressure Drug Shows Promise for Treating ALS
    Terazosin, a drug currently approved to treat high blood pressure and enlarged prostate, may also be able to treat ALS. ...
    Written By: Annie Lennon
    1
     
     
  • AUG 16, 2022
    Neuroscience
    A Common Denominator Among All Forms of ALS is Revealed
    A Common Denominator Among All Forms of ALS is Revealed
    ALS (amyotrophic lateral sclerosis) is a motor neuron disease, which gradually causes a loss of movement. Eventually, pa ...
    Written By: Carmen Leitch
    1
    JUL 18, 2022
    Neuroscience
    Researchers See the Formation of Motor Memories in Mice
    Researchers See the Formation of Motor Memories in Mice
    People usually only have to learn how to ride a bicycle once; and once a person learns how, they can get on and start ri ...
    Written By: Carmen Leitch
    3
    MAY 25, 2022
    Neuroscience
    Exploring Drug Targets in Neurodegenerative Diseases
    Exploring Drug Targets in Neurodegenerative Diseases
    Introduction Life expectancy has increased globally over the last several decades. However, longer life expectancy comes ...
    Sponsored By: Sino Biological
    3
    MAY 19, 2022
    Drug Discovery & Development
    Experimental Drug Shows Promise Against ALS
    Experimental Drug Shows Promise Against ALS
    A new experimental drug known as NU-9 may be more effective in treating ALS than existing FDA-approved drugs. The corres ...
    Written By: Annie Lennon
    1
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