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    Toxicity studies

    Toxicity studies identify the toxic effects of a drug by studying how it impacts cells or organs within the body. Toxicity studies evaluate both cellular damage but also potential impairment of organ function. These studies often evaluate increasing doses of the drug of interest to determine the highest dose which may be administered safely.

    Trending News

    • MAR 26, 2015
      Neuroscience
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      Study of Thousands of Brains Reveals Tau as Driver of Alzheimer's
      By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Roch ...
      Written By: Ilene Schneider
      4
      MAR 24, 2015
      Earth & The Environment
      There's gold in them there biosolids!
      There's gold in them there biosolids!
      The alchemists thought they could turn lead into gold. Maybe they should have focused on baser material.

      As ...
      Written By: Robert Woodard
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      MAR 24, 2015
      Plants & Animals
      Snake Anti-Venom Could Come From Opossums
      Snake Anti-Venom Could Come From Opossums
      Aside from giving us the phrase "to play possum," it could be argued opossums haven't really contributed all that much t ...
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      MAR 18, 2015
      Cancer
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      Tiny Diamonds--A Cancer Cell's Best Friend?
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      MAR 16, 2015
      Microbiology
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      MAR 16, 2015
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      Does Amyloid Kill in Alzheimer's, Heal in MS?
      Does Amyloid Kill in Alzheimer's, Heal in MS?
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      MAR 12, 2015
      Genetics & Genomics
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      MAR 10, 2015
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      Bacteria ‘Hotwire Their Genes' to Mend Faulty Motor
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      FEB 25, 2015
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      Small Molecule May Help Reduce Cancer in At-Risk Population
      Small Molecule May Help Reduce Cancer in At-Risk Population
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      FEB 25, 2015
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      FEB 17, 2015
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      Squid Can Edit Their Own Gene Sequences
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      Penn Medicine Study Offers Promising Treatment Option and Improved Survival Rates  for Patients with BRCA-Related Ovarian, Breast, Pancreatic, and Prostate Cancers
      Penn Medicine Study Offers Promising Treatment Option and Improved Survival Rates for Patients with BRCA-Related Ovarian, Breast, Pancreatic, and Prostate Cancers
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      NOV 05, 2014
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      JUL 18, 2014
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      UCI Researchers Study Way to Block Botulism
      UCI Researchers Study Way to Block Botulism
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      JUN 25, 2014
      Earth & The Environment
      New Processes Could Kill Two Birds with One Stone
      New Processes Could Kill Two Birds with One Stone
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      DEC 07, 2013
      Neuroscience
      Alzheimer's Risk Gene May Begin to Affect Brains in Childhood, Research Shows
      Alzheimer's Risk Gene May Begin to Affect Brains in Childhood, Research Shows
      People who carry a high-risk gene for Alzheimer's disease show changes in their brains beginning in childhood, decades b ...
      Written By: Jen Ellis
      0
    MAR 26, 2015
    Neuroscience
    Study of Thousands of Brains Reveals Tau as Driver of Alzheimer's
    Study of Thousands of Brains Reveals Tau as Driver of Alzheimer's
    By examining more than 3,600 postmortem brains, researchers at Mayo Clinic's campuses in Jacksonville, Florida, and Roch ...
    Written By: Ilene Schneider
    4
    MAR 24, 2015
    Earth & The Environment
    There's gold in them there biosolids!
    There's gold in them there biosolids!
    The alchemists thought they could turn lead into gold. Maybe they should have focused on baser material.

    As ...
    Written By: Robert Woodard
    4
    MAR 24, 2015
    Plants & Animals
    Snake Anti-Venom Could Come From Opossums
    Snake Anti-Venom Could Come From Opossums
    Aside from giving us the phrase "to play possum," it could be argued opossums haven't really contributed all that much t ...
    Written By: Brenda Kelley Kim
    8
    MAR 18, 2015
    Cancer
    Tiny Diamonds--A Cancer Cell's Best Friend?
    Tiny Diamonds--A Cancer Cell's Best Friend?
    Cancer stem cells often cause tumors to form and are particularly difficult to destroy. They resist chemotherapy, allowi ...
    Written By: Will Hector
    6
    MAR 16, 2015
    Microbiology
    Bacteria inspires nerve gas neutralizer
    Bacteria inspires nerve gas neutralizer
    A robust new material is extraordinarily adept at destroying toxic nerve agents that were first used 100 years ago durin ...
    Written By: Will Hector
    7
     
     
  • MAR 16, 2015
    Neuroscience
    Does Amyloid Kill in Alzheimer's, Heal in MS?
    Does Amyloid Kill in Alzheimer's, Heal in MS?
    Two groups have recently made strides with amyloid beta (aβ), the supposed main villain in Alzheimer's disease. But whil ...
    Written By: Ilene Schneider
    6
    MAR 12, 2015
    Genetics & Genomics
    Scientists Sequence Genome of Classical Hodgkin Lymphoma
    Scientists Sequence Genome of Classical Hodgkin Lymphoma
    A team of researchers has sequenced the genome of classical Hodgkin lymphoma, illuminating exactly which proteins are al ...
    Written By: Ilene Schneider
    7
    MAR 10, 2015
    Cell & Molecular Biology
    Heart on a Chip Instead of a Sleeve?
    Heart on a Chip Instead of a Sleeve?
    BERKELEY -
    When UC Berkeley bioengineers say they are holding their hearts in the palms of their hands, they are no ...
    Written By: Brenda Kelley Kim
    5
    FEB 27, 2015
    Microbiology
    Bacteria ‘Hotwire Their Genes' to Mend Faulty Motor
    Bacteria ‘Hotwire Their Genes' to Mend Faulty Motor
    Researchers at the University of York, UK, are part of a team of scientists that has discovered how bacteria can restart ...
    Written By: Judy O'Rourke
    7
    FEB 25, 2015
    Cell & Molecular Biology
    Small Molecule May Help Reduce Cancer in At-Risk Population
    Small Molecule May Help Reduce Cancer in At-Risk Population
    Scientists have shown that small molecules can "hijack" enzyme function in mice, suggesting a possible preventive mechan ...
    Written By: Ilene Schneider
    5
     
     
  • FEB 25, 2015
    Cancer
    Technology Optimizes Cancer Therapy with Nanomedicine Drug Combinations
    Technology Optimizes Cancer Therapy with Nanomedicine Drug Combinations
    In greater than 90 percent of cases in which treatment for metastatic cancer fails, the reason is that the cancer is res ...
    Written By: Ilene Schneider
    6
    FEB 17, 2015
    Genetics & Genomics
    Squid Can Edit Their Own Gene Sequences
    Squid Can Edit Their Own Gene Sequences
    The gradual modification of a species' structures and features, otherwise known as the principle of adaptation, is one o ...
    Written By: Ilene Schneider
    7
    NOV 18, 2014
    Cancer
    Penn Medicine Study Offers Promising Treatment Option and Improved Survival Rates  for Patients with BRCA-Related Ovarian, Breast, Pancreatic, and Prostate Cancers
    Penn Medicine Study Offers Promising Treatment Option and Improved Survival Rates for Patients with BRCA-Related Ovarian, Breast, Pancreatic, and Prostate Cancers
    Olaparib, an experimental twice-daily oral cancer drug, produces an overall tumor response rate of 26 percent in several ...
    Written By: Ilene Schneider
    3
    NOV 05, 2014
    Neuroscience
    Scientists Engineer First Human Brain Cells with Alzheimer
    Scientists Engineer First Human Brain Cells with Alzheimer
    Researchers from the Genetics and Aging Research Unit at Massachusetts General Hospital (MGH) have created what they Alz ...
    Written By: Ilene Schneider
    2
    OCT 30, 2014
    Cancer
    Cancer Study In Mice Brings Hope For Human Patients
    Cancer Study In Mice Brings Hope For Human Patients
    A study conducted at the University of Chicago's Center for Personalized Therapeutics has shown remarkable results in el ...
    Written By: Brenda Kelley Kim
    2
     
     
  • AUG 18, 2014
    Cancer
    Stealth Combination Attacks Cancer
    Stealth Combination Attacks Cancer
    Combination therapies, or "drug cocktails," are part of modern anti-cancer treatments today. The more researchers learn ...
    Written By: Ilene Schneider
    3
    JUL 18, 2014
    Microbiology
    UCI Researchers Study Way to Block Botulism
    UCI Researchers Study Way to Block Botulism
    UC Irvine School of Medicine researchers have learned how bacterial toxins that cause food-borne botulism are absorbed t ...
    Written By: Ilene Schneider
    3
    JUN 25, 2014
    Earth & The Environment
    New Processes Could Kill Two Birds with One Stone
    New Processes Could Kill Two Birds with One Stone
    CO2, which is generally accepted as being the leading cause of climate change, has been increasing in the atmosphere for ...
    Written By: Peter Micheli
    2
    DEC 07, 2013
    Neuroscience
    Alzheimer's Risk Gene May Begin to Affect Brains in Childhood, Research Shows
    Alzheimer's Risk Gene May Begin to Affect Brains in Childhood, Research Shows
    People who carry a high-risk gene for Alzheimer's disease show changes in their brains beginning in childhood, decades b ...
    Written By: Jen Ellis
    0
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