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Toxicity studies
Toxicity studies identify the toxic effects of a drug by studying how it impacts cells or organs within the body. Toxicity studies evaluate both cellular damage but also potential impairment of organ function. These studies often evaluate increasing doses of the drug of interest to determine the highest dose which may be administered safely.
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JUL 15, 2015Microbiology
Clostridium difficile is most commonly referred to as a healthcare-associated infection (HAI), with at risk-populations ...Written By: Sarah HertrichJUL 09, 2015Cancer
Powerful diseases require powerful drugs or powerful doses of drugs, often with severe side effects. An optical control ...Written By: Ilene SchneiderJUL 08, 2015Earth & The Environment
Oregon's environmental regulatory agency, the Environmental Quality Commission, is heavily regulating the state's coal-f ...Written By: Andrew J. DunlopJUL 03, 2015Neuroscience
Are the very systems that are supposed to dispose of cellular waste making it worse? A study at Yale University in New H ...Written By: Ilene SchneiderJUN 22, 2015Neuroscience
Young children living in stressful family situations show the effects of cortisol, known as "the stress hormone," on the ...Written By: Ilene SchneiderJUN 15, 2015Cancer
The best way to keep an aggressive disease at bay may be on your spice rack, not in your medicine cabinet. You probably ...Written By: Ilene SchneiderJUN 03, 2015Neuroscience
Poor sleep may cause the beta-amyloid protein to trigger Alzheimer's disease by attacking the brain's long-term memory, ...Written By: Ilene SchneiderMAY 24, 2015Health & Medicine
Obesity has long been a global epidemic with an estimated 2.8 million people dying each year from associated complicatio ...Written By: Jennifer EllisMAY 22, 2015Plants & Animals
The massive oil leak in the spring of 2010 devastated coastlines along the Gulf of Mexico and its effects will likely co ...Written By: Brenda Kelley KimAPR 27, 2015Neuroscience
Researchers have identified how proteins that play a key role in Alzheimer's disease are linked in a pathway that contro ...Written By: Ilene SchneiderAPR 23, 2015Genetics & Genomics
A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, includin ...Written By: Ilene SchneiderAPR 23, 2015Genetics & Genomics
In 2013, University at Buffalo researchers published a paper showing how slowing down protein synthesis can improve myel ...Written By: Ilene SchneiderAPR 14, 2015Cancer
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has p ...Written By: Robert WoodardAPR 10, 2015Cancer
Biologists at MIT and the Whitehead Institute have discovered a vulnerability of brain cancer cells that could be exploi ...Written By: Ilene SchneiderAPR 08, 2015Immunology
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, accord ...Written By: Will HectorAPR 06, 2015Cancer
Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing ge ...Written By: Ilene SchneiderAPR 03, 2015Cancer
Cancer treatments that harness the body's immune system to wipe out tumors have begun paying off for some patients for w ...Written By: Will HectorAPR 02, 2015Microbiology
The Bacillus cereus bacteria is one of the potential causes of food poisoning. Indeed, a recent study in Analytical and ...Written By: Robert WoodardAPR 02, 2015Genetics & Genomics
As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel ...Written By: Ilene SchneiderAPR 01, 2015Genetics & Genomics
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the "caps" or ...Written By: Ilene SchneiderAPR 01, 2015Neuroscience
Researchers from the Children's Hospital of Los Angeles have been looking into the effects of air pollution. While it sh ...Written By: Robert WoodardMAR 31, 2015Cancer
Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice ...Written By: Ilene SchneiderMAR 30, 2015Neuroscience
New research has identified some of the processes by which molecules associated with neurological diseases can disrupt t ...Written By: Ilene SchneiderMAR 30, 2015Cancer
Nearly 50 years after the "war on cancer" was declared in the United States, precision medicine presages an era of incre ...Written By: Ilene Schneider
JUL 15, 2015
Microbiology
Clostridium difficile is most commonly referred to as a healthcare-associated infection (HAI), with at risk-populations
...
Written By:
Sarah Hertrich
JUL 09, 2015
Cancer
Powerful diseases require powerful drugs or powerful doses of drugs, often with severe side effects. An optical control
...
Written By:
Ilene Schneider
JUL 08, 2015
Earth & The Environment
Oregon's environmental regulatory agency, the Environmental Quality Commission, is heavily regulating the state's coal-f
...
Written By:
Andrew J. Dunlop
JUL 03, 2015
Neuroscience
Are the very systems that are supposed to dispose of cellular waste making it worse? A study at Yale University in New H
...
Written By:
Ilene Schneider
JUN 22, 2015
Neuroscience
Young children living in stressful family situations show the effects of cortisol, known as "the stress hormone," on the
...
Written By:
Ilene Schneider
JUN 15, 2015
Cancer
The best way to keep an aggressive disease at bay may be on your spice rack, not in your medicine cabinet. You probably
...
Written By:
Ilene Schneider
JUN 03, 2015
Neuroscience
Poor sleep may cause the beta-amyloid protein to trigger Alzheimer's disease by attacking the brain's long-term memory,
...
Written By:
Ilene Schneider
MAY 24, 2015
Health & Medicine
Obesity has long been a global epidemic with an estimated 2.8 million people dying each year from associated complicatio
...
Written By:
Jennifer Ellis
MAY 22, 2015
Plants & Animals
The massive oil leak in the spring of 2010 devastated coastlines along the Gulf of Mexico and its effects will likely co
...
Written By:
Brenda Kelley Kim
APR 27, 2015
Neuroscience
Researchers have identified how proteins that play a key role in Alzheimer's disease are linked in a pathway that contro
...
Written By:
Ilene Schneider
APR 23, 2015
Genetics & Genomics
A significant proportion of children with chronic kidney disease (CKD) have unsuspected chromosomal imbalances, includin
...
Written By:
Ilene Schneider
APR 23, 2015
Genetics & Genomics
In 2013, University at Buffalo researchers published a paper showing how slowing down protein synthesis can improve myel
...
Written By:
Ilene Schneider
APR 14, 2015
Cancer
An experimental drug that attacks brain tumor tissue by crippling the cells' energy source called the mitochondria has p
...
Written By:
Robert Woodard
APR 10, 2015
Cancer
Biologists at MIT and the Whitehead Institute have discovered a vulnerability of brain cancer cells that could be exploi
...
Written By:
Ilene Schneider
APR 08, 2015
Immunology
An over-the-counter drug indicated to treat allergy symptoms limited hepatitis C virus activity in infected mice, accord
...
Written By:
Will Hector
APR 06, 2015
Cancer
Northwestern Medicine scientists have identified a small RNA molecule called miR-182 that can suppress cancer-causing ge
...
Written By:
Ilene Schneider
APR 03, 2015
Cancer
Cancer treatments that harness the body's immune system to wipe out tumors have begun paying off for some patients for w
...
Written By:
Will Hector
APR 02, 2015
Microbiology
The Bacillus cereus bacteria is one of the potential causes of food poisoning. Indeed, a recent study in Analytical and
...
Written By:
Robert Woodard
APR 02, 2015
Genetics & Genomics
As a patient prepares to become the first in history to receive his own genetically engineered stem cells for sickle cel
...
Written By:
Ilene Schneider
APR 01, 2015
Genetics & Genomics
Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the "caps" or
...
Written By:
Ilene Schneider
APR 01, 2015
Neuroscience
Researchers from the Children's Hospital of Los Angeles have been looking into the effects of air pollution. While it sh
...
Written By:
Robert Woodard
MAR 31, 2015
Cancer
Fasting in combination with chemotherapy has already been shown to kill cancer cells, but a pair of new studies in mice
...
Written By:
Ilene Schneider
MAR 30, 2015
Neuroscience
New research has identified some of the processes by which molecules associated with neurological diseases can disrupt t
...
Written By:
Ilene Schneider
MAR 30, 2015
Cancer
Nearly 50 years after the "war on cancer" was declared in the United States, precision medicine presages an era of incre
...
Written By:
Ilene Schneider