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    Triplet expansions

    In genetics, triplets are described as a type of mutation characterized by repeats of three nucleotides. Triplet expansions, or trinucleotide repeat expansion, occur when more triplets are present in a mutated gene than in the normal gene. As diseases related to triplets are inherited, the number of triplets continues to increase. Diseases including Fragile X Syndrome, Spinal muscular atrophy, and Huntington's disease are caused by triple repeats in genes.

    Trending News

    • JUN 03, 2025
      Genetics & Genomics
      A Gene Editing Strategy to Repair Huntington's Defects
      A Gene Editing Strategy to Repair Huntington's Defects
      Researchers have developed a gene editing strategy that can repair the genetic problems that lead to Huntington's diseas ...
      Written By: Carmen Leitch
      3
      JAN 12, 2023
      Cell & Molecular Biology
      Clumpy RNA Can Cause Major Problems for Cells
      Clumpy RNA Can Cause Major Problems for Cells
      The nucleotide bases of our DNA are read in triplets, and three nucleotides together, called a codon, represents an amin ...
      Written By: Carmen Leitch
      2
      NOV 13, 2017
      Clinical & Molecular DX
      Improving the Detection of Fragile-X Syndrome
      Improving the Detection of Fragile-X Syndrome
      Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X ...
      Written By: Xuan Pham
      1
      DEC 12, 2016
      Health & Medicine
      TSRI Scientists Devise New Approaches to Personalized Medicines
      TSRI Scientists Devise New Approaches to Personalized Medicines
      JUPITER, FL – December 12, 2016 – Scientists on the Florida campus of The Scripps Research Institute (TSRI) ...
      Written By: The Scripps Research Institute (TSRI)
      5
    JUN 03, 2025
    Genetics & Genomics
    A Gene Editing Strategy to Repair Huntington's Defects
    A Gene Editing Strategy to Repair Huntington's Defects
    Researchers have developed a gene editing strategy that can repair the genetic problems that lead to Huntington's diseas ...
    Written By: Carmen Leitch
    3
    JAN 12, 2023
    Cell & Molecular Biology
    Clumpy RNA Can Cause Major Problems for Cells
    Clumpy RNA Can Cause Major Problems for Cells
    The nucleotide bases of our DNA are read in triplets, and three nucleotides together, called a codon, represents an amin ...
    Written By: Carmen Leitch
    2
    NOV 13, 2017
    Clinical & Molecular DX
    Improving the Detection of Fragile-X Syndrome
    Improving the Detection of Fragile-X Syndrome
    Repeat sequences are common in our DNA, and are known to cause human disorders. In particular, a triplet repeat on the X ...
    Written By: Xuan Pham
    1
    DEC 12, 2016
    Health & Medicine
    TSRI Scientists Devise New Approaches to Personalized Medicines
    TSRI Scientists Devise New Approaches to Personalized Medicines
    JUPITER, FL – December 12, 2016 – Scientists on the Florida campus of The Scripps Research Institute (TSRI) ...
    Written By: The Scripps Research Institute (TSRI)
    5
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