FEB 01, 2019 10:55 AM PST

Can Israeli Company Keep its Promise for a Cure For Cancer?

WRITTEN BY: Amy Loriaux

Accelerated Evolution Biotechnology, Ltd. (AEBI), an Israeli company led by CEO Dr. Ilan Morad, made some bold claims on January 29th, 2019, about its company's ability to cure cancer "within [a] year's time". This was stated by Dan Aridor, the company's Chairman of the Board. AEBI's technology is based on its new cancer-fighting technology and its ability to find potential targets using SoAP, a technique which uses viral-mediated gene transfer to infect cells.

Photo source: Adobe Shutterstock (used with permission)

The therapy then uses a multi-target toxin (MuTaTo) to find those infected cells (putative cancer cells) and kills them. This is, in effect, an anti-biotic for tumor cells, at least that is what Dan Aridor, the company's Chairman of the Board, said in The Jerusalem Post. The company has already been granted a US patent for AEBI's SoAP-based platform and has shown proof of concept using human epithelial carcinoma cells.

In essence, these promises are based solely on nonclinical results. The group has yet to publish their results in a peer-reviewed (the golden standard for authenticity) journal. Many oncologists are doubtful that the science will actually go anywhere, one spokesperson for Duke Health calling this a "non-story". Another researcher was quoted as stating “As someone with 10 years of molecular biology and medical experience, I strongly suspect the Israeli scientists…are completely misrepresenting their supposed discovery." He went on to call-out snake oil on the claim.

Photo source: UnSplash.com

Some scientists are very concerned that this could raise false hope in the estimated 1,735,350 people who were predicted to be diagnosed in 2018. Some researchers are even incensed. "I really think that it's really unfair and almost cruel to bandy about these likely to be false hopes to cancer patients," stated Dr. Benjamin Neel, the director of the Laura and Isaac Perlmutter Cancer Center at New York University Langone Health. He went on to say, "When they present it for peer review and it's published in a respectable journal and we can look at it, then that will be another story". 

Aridor said AEBi does not publish in peer review papers. The company did give "detailed lectures" on its progress and findings in three Drug Discovery conferences in 2017 and 2018, and added it received "wonderful reviews." However, since these data are nonclinical, the company will need many more years of research and funding to be approved for use in the US. Pre-clinical animal trials, three phases of clinical trials, and much more data will have to be gathered. In essence, this technology will not be available, at least in the States, in one year's time.

Sources: http://www.aebi-bio.com/, www.6abc.com, Applied and Environmental Microbiology, The Jerusalem Post, www.LinkedIn.com, www.cancer.gov

About the Author
  • I currently work at a small CRO involved in clinical trial management.
You May Also Like
NOV 16, 2019
Cell & Molecular Biology
NOV 16, 2019
Telomerase Enzyme Found to Have a Protective Role
Telomerase was thought to be active primarily in cells that divide a lot, but new research has found, however, that telomerase has another role....
NOV 23, 2019
Cancer
NOV 23, 2019
Can lithium heal damage from radiation?
Research suggests that lithium could play a role in minimizing the negative effects of radiation on the brain. The research was published in Molecular Psyc...
DEC 18, 2019
Cancer
DEC 18, 2019
Looking to this tropical plant for future pancreatic cancer treatments
Pancreatic cancer is a dangerous disease for two reasons: its stealth and its resistance to many anti-cancer drugs. The American Cancer Society estimates t...
JAN 02, 2020
Drug Discovery & Development
JAN 02, 2020
FDA Approves Ovarian Cancer Drug to Treat Pancreatic Cancer
In 2019, an estimated 46,000 Americans died from pancreatic cancer. Now, the Food and Drug Administration (FDA) has approved Lynparza, an ovarian cancer dr...
JAN 02, 2020
Genetics & Genomics
JAN 02, 2020
Mysterious Extrachromosomal DNA is Linked to Childhood Cancer
Scientists are learning more about an unusual kind of DNA that's separate from a cell's genomic DNA....
JAN 15, 2020
Clinical & Molecular DX
JAN 15, 2020
Laser microchip picks up cancer markers in urine
A future where patients no longer need to endure expensive, painful and complicated cancer tests could soon become a reality. Researchers have developed a...
Loading Comments...