Drug Discovery
Drug Discovery: drug discovery is the process by which new candidate medications are discovered. Historically, drugs were discovered through identifying the active ingredient from traditional remedies or by serendipitous discovery. Modern drug discovery involves the identification of screening hits, medicinal chemistry and optimization of those hits to increase the affinity, selectivity (to reduce the potential of side effects), efficacy/potency, metabolic stability (to increase the half-life), and oral bioavailability.
What's Popular in Drug Discovery
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NOV 15, 2018Drug Discovery
NOV 15, 2018At Karolinska Institutet in Sweden, a team of scientists from multiple disciplines have worked together to develop an inflammation inhibitor. The new anti-...Written By: Nouran AminNOV 15, 2018Drug Discovery
NOV 15, 2018Neuroblastoma is one of the most common childhood cancers and the leading cause of cancer deaths among pediatric patients younger than 5. The cancer is fre...Written By: Nouran AminNOV 15, 2018Drug Discovery
NOV 15, 2018A common condition of the nervous system, Restless Leg Syndrome (RLS) is the overwhelming urge to move the legs. Usually unpleasant symptoms, many RLS pati...Written By: Nouran AminNOV 15, 2018Drug Discovery
NOV 15, 2018In a publication in Trends in Pharmacological Sciences, a subclass of anti-aging compounds, called geroneuroprotectors (GNPs), have been identified in rese...Written By: Nouran AminNOV 13, 2018Cell & Molecular Biology
NOV 13, 2018Cells have a barrier around them, which carefully controls what can move across it. That presents a challenge in pharmaceutical design....Written By: Carmen Leitch
NOV 15, 2018
Drug Discovery
NOV 15, 2018
At Karolinska Institutet in Sweden, a team of scientists from multiple disciplines have worked together to develop an inflammation inhibitor. The new anti-...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery
NOV 15, 2018
Neuroblastoma is one of the most common childhood cancers and the leading cause of cancer deaths among pediatric patients younger than 5. The cancer is fre...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery
NOV 15, 2018
A common condition of the nervous system, Restless Leg Syndrome (RLS) is the overwhelming urge to move the legs. Usually unpleasant symptoms, many RLS pati...
Written By:
Nouran Amin
NOV 15, 2018
Drug Discovery
NOV 15, 2018
In a publication in Trends in Pharmacological Sciences, a subclass of anti-aging compounds, called geroneuroprotectors (GNPs), have been identified in rese...
Written By:
Nouran Amin
NOV 13, 2018
Cell & Molecular Biology
NOV 13, 2018
Cells have a barrier around them, which carefully controls what can move across it. That presents a challenge in pharmaceutical design....
Written By:
Carmen Leitch
NOV 13, 2018
Drug Discovery
NOV 13, 2018
Niemann-Pick type C (NPC) is a rare and fatal neurodegenerative disease. Symptoms of the condition include loss of balance, difficulty swallowing, seizures...
Written By:
Nouran Amin
NOV 12, 2018
Cancer
NOV 12, 2018
Primary malignant liver tumors are rare in children with an occurrence rate of 1-2% of all childhood cancers. Radical surgical resection of the liver which means the removal of part of the li...
Written By:
Heba El Wassef
NOV 10, 2018
Genetics & Genomics
NOV 10, 2018
Directed evolution is a Nobel-prize winning technique that has now been simplified and accelerated....
Written By:
Carmen Leitch
NOV 08, 2018
Health & Medicine
NOV 08, 2018
The benefits of aspirin use in patients with known cardiovascular disease (CVD) are well-established. A 2015 meta-analysis reviewed data gathered from 118,...
Written By:
Abbie Arce
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NOV 15, 2018 04:00 AM PST
NOV 15, 2018 04:00 AM PSTDevelopment of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...Speaker: Ryan HicksPresented At:6th annual 24 Hours of Stem Cells™ virtual eventNOV 15, 2018 07:00 AM PST
NOV 15, 2018 07:00 AM PSTThe use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...Speaker: Filip RoudnickyPresented At:6th annual 24 Hours of Stem Cells™ virtual eventNOV 15, 2018 08:00 AM PST
NOV 15, 2018 08:00 AM PSTCRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...Speaker: Kris SahaPresented At:6th annual 24 Hours of Stem Cells™ virtual eventNOV 15, 2018 09:00 AM PST
NOV 15, 2018 09:00 AM PSTWatch how to passage feeder-free Pluripotent Stem Cells (PSCs) cultured in Essential 8 medium using EDTA. Learn the best practices to help ensure successful passage of your cells....Speaker: Chad MacArthurPresented At:6th annual 24 Hours of Stem Cells™ virtual eventNOV 15, 2018 10:00 AM PSTC.E. CREDITS
NOV 15, 2018 10:00 AM PSTDATE: November 15, 2018TIME: 10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...Speaker: Traci DeGeer , Alexander KlimowiczSponsored By: Leica Biosystems
NOV 15, 2018
04:00 AM PST
NOV 15, 2018
04:00 AM PST
Development of physiologically relevant cellular models, with strong translatability to human pathophysiology, is critical for identification and validation of novel therapeutic targets. Cell...
Speaker:
Ryan Hicks
Presented At:6th annual 24 Hours of Stem Cells™ virtual event
NOV 15, 2018
07:00 AM PST
NOV 15, 2018
07:00 AM PST
The use of human pluripotent stem cells (hPSCs) for in vitro disease-modeling is limited by the lack of robust and efficient protocols for the differentiation of relevant adult cell types. Pr...
Speaker:
Filip Roudnicky
Presented At:6th annual 24 Hours of Stem Cells™ virtual event
NOV 15, 2018
08:00 AM PST
NOV 15, 2018
08:00 AM PST
CRISPR ribonucleoproteins (RNPs) can generate programmable gene edits, however imprecise editing and efficient delivery to human stem cells are key challenges. Here we describe novel biochemi...
Speaker:
Kris Saha
Presented At:6th annual 24 Hours of Stem Cells™ virtual event
NOV 15, 2018
09:00 AM PST
NOV 15, 2018
09:00 AM PST
Watch how to passage feeder-free Pluripotent Stem Cells (PSCs) cultured in Essential 8 medium using EDTA. Learn the best practices to help ensure successful passage of your cells....
Speaker:
Chad MacArthur
Presented At:6th annual 24 Hours of Stem Cells™ virtual event
NOV 15, 2018
10:00 AM PST
C.E. CREDITS
NOV 15, 2018
10:00 AM PST
DATE: November 15, 2018TIME: 10:00am PT, 1:00pm ET Multiplex fluorescence immunohistochemistry offers a window into the biology of human disease, enabling the ana...
Speaker:
Traci DeGeer
,
Alexander Klimowicz
Sponsored By: Leica Biosystems
NOV 21, 2018
09:00 AM PST
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C.E. CREDITS
NOV 21, 2018
09:00 AM PST
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DATE: November 21,2018TIME: 09:00am PST, 12:00pm EST Vaginal infections are a source of considerable morbidity among women. It is estimated that there are more than 10...
Speaker:
Christina Muzny, MD, MSPH, FACP
Sponsored By: Roche Molecular Diagnostics
DEC 05, 2018
09:00 AM PST
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C.E. CREDITS
DEC 05, 2018
09:00 AM PST
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DATE: December 5, 2018TIME: 9:00AM PDTThe mouse is a critical, increasingly used model system in biomedical research and preclinical drug discovery. While technological advances en...
Speaker:
Daniel Braunschweig, PhD
Sponsored By: Luminex
DEC 06, 2018
10:00 AM CET
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C.E. CREDITS
DEC 06, 2018
10:00 AM CET
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DATE: December 6, 2018TIME: 10:00am CET, 5:00pm CST Intro Micro-computed tomography (micro-CT) offers significant advantage...
Speaker:
Rob van 't Hof, BSc, MSc, PhD
Sponsored By: Bruker
DEC 06, 2018
11:00 AM EST
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C.E. CREDITS
DEC 06, 2018
11:00 AM EST
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DATE: December 6, 2018TIME: 11:00am EST, 5:00pm CET Introduction Micro-computed tomography (micro-CT) offers significant advantages o...
Speaker:
Rob van 't Hof, BSc, MSc, PhD
Sponsored By: Bruker
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JAN 31, 2019 06:00 AM PSTAdd to Calendar Select one of the following:
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LabRoots announces a new addition to our virtual conference line up for 2019, BioProcessing! Join us for this free, one-day event on January 31st as we discuss upstream and downstream process...FEB 13, 2019 06:00 AM PSTAdd to Calendar Select one of the following:
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LabRoots, along with the Laboratory Animal Science (LAS) planning committee, are pleased announce the 8th annual Laboratory Animal Science virtual conference! LabRoots will host this two-day,...FEB 27, 2019 06:00 AM PSTAdd to Calendar Select one of the following:
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FEB 27, 2019 06:00 AM PSTAdd to Calendar Select one of the following:
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After a hugely successful inaugural year, LabRoots and the Drug Discovery planning committee are pleased to announce the 2nd annual Drug Discovery Virtual conference. LabRoots will host the t...MAR 27, 2019 06:00 AM PDTAdd to Calendar Select one of the following:
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MAR 27, 2019 06:00 AM PDTAdd to Calendar Select one of the following:
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For the second year in a row, LabRoots is pleased to announce the 2019 Cannabis Sciences Virtual Event. LabRoots will host the 2nd annual event March 27-28, 2019.The Cannabis Sciences plannin...MAY 30, 2019 06:00 AM PDTAdd to Calendar Select one of the following:
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MAY 30, 2019 06:00 AM PDTAdd to Calendar Select one of the following:
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Welcome to the 3rd Annual Laboratory Automation Virtual Event; a free virtual conference for professionals interested in the most recent technologies for today’s labs. Laboratory automa...
JAN 31, 2019
06:00 AM PST
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JAN 31, 2019
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LabRoots announces a new addition to our virtual conference line up for 2019, BioProcessing! Join us for this free, one-day event on January 31st as we discuss upstream and downstream process...
FEB 13, 2019
06:00 AM PST
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FEB 13, 2019
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LabRoots, along with the Laboratory Animal Science (LAS) planning committee, are pleased announce the 8th annual Laboratory Animal Science virtual conference! LabRoots will host this two-day,...
FEB 27, 2019
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FEB 27, 2019
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After a hugely successful inaugural year, LabRoots and the Drug Discovery planning committee are pleased to announce the 2nd annual Drug Discovery Virtual conference. LabRoots will host the t...
MAR 27, 2019
06:00 AM PDT
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MAR 27, 2019
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For the second year in a row, LabRoots is pleased to announce the 2019 Cannabis Sciences Virtual Event. LabRoots will host the 2nd annual event March 27-28, 2019.The Cannabis Sciences plannin...
MAY 30, 2019
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MAY 30, 2019
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Welcome to the 3rd Annual Laboratory Automation Virtual Event; a free virtual conference for professionals interested in the most recent technologies for today’s labs. Laboratory automa...
JUN 20, 2019
06:00 AM PDT
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JUN 20, 2019
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LabRoots and the Precision Medicine Planning Committee are pleased to announce the 4th Annual Precision Medicine Virtual Event. Precision Medicine 2019, a two-day event held June 19-20, will...
NOV 14, 2018
NOV 14, 2018
Register for free to attend the 6th annual Gibco™ 24 Hours of Stem Cells™ virtual event, the largest global virtual stem cell event taking place around the world on November 15, 2...
OCT 10, 2018
06:00 AM PDT
C.E. CREDITS
OCT 10, 2018
06:00 AM PDT
The 6th Annual Cancer Research & Oncology Virtual Event will take place October 2018. The free, two-day online event will bring research professionals, scientists, and clinicians from aro...
OCT 03, 2018
06:00 AM PDT
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OCT 03, 2018
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LabRoots invites you to the First Annual CRISPR Virtual Event! With continued adoption and integration in research labs, CRISPR gene editing has gained importance both as a research tool in d...
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