JUN 17, 2019 9:50 AM PDT

AI Improves Lung Cancer Detection in MIT Study

WRITTEN BY: Julia Travers

Lung cancer led to an estimated 160,000 deaths in 2018 in the U.S., making it the country’s leading cause of cancer-related deaths. Early detection can play a big role in patients’ prognosis and survival, and a new algorithm out of MIT seeks to improve the lung cancer screening process. While still in its early stages, the “three-dimensional deep learning” process has had some promising results detecting lung cancer, beating out radiologists in some instances. The related study, “End-to-end lung cancer screening with three-dimensional deep learning on low-dose chest computed tomography,” was published in the journal Nature in late May 2019.

A Google researcher named Danial Tse developed the algorithm that was used in the study. Tse and his colleagues trained the deep learning algorithm to look for malignant lung nodules with more than 42,000 computed tomography (CT) scans. During this study, the algorithm was used with 6,716 National Lung Cancer screening trial cases. The model used the patients’ current and prior CT volumes to predict their lung cancer risk.

Lung illustration, credit: public domain

When prior CT imaging for patients was not available, the MIT model outperformed six participating radiologists, coming up with 11 percent fewer false positives and 5 percent fewer false negatives. When prior CT data for patients was available, the AI’s performance was on-par with these same radiologists.

“This creates an opportunity to optimize the screening process via computer assistance and automation. While the vast majority of patients remain unscreened, we show the potential for deep learning models to increase the accuracy, consistency and adoption of lung cancer screening worldwide,” the authors state.

AI is also being evaluated and used as a means of finding other cancers, including those of the breast and skin. This research contributes more data to the growing body of evidence that AI can play a meaningful role in medicine. Tse and colleagues “acknowledge that the work needs to be validated on larger patient populations,” according to MIT Technology Review.

The video below offers a basic introduction to CT scans.

 

Sources: Nature, MIT Technology Review

 

About the Author
  • Julia Travers is a writer, artist and teacher. She frequently covers science, tech, conservation and the arts. She enjoys solutions journalism. Find more of her work at jtravers.journoportfolio.com.
You May Also Like
JUN 08, 2020
Cell & Molecular Biology
How Cancer Cells Use Inflammation as a Shield Against Viruses
JUN 08, 2020
How Cancer Cells Use Inflammation as a Shield Against Viruses
Microorganisms called oncolytic viruses can infect and kill cancer cells while leaving healthy cells alone.
JUN 09, 2020
Cancer
Genetic counseling for prostate cancer testing goes telehealth
JUN 09, 2020
Genetic counseling for prostate cancer testing goes telehealth
Genetic testing for prostate cancer in men is not yet commonplace, despite the positive impact that it could have on dec ...
JUN 20, 2020
Cancer
A New MicroRNA Linked to the Suppression of Ovarian Cancer
JUN 20, 2020
A New MicroRNA Linked to the Suppression of Ovarian Cancer
One of the things a cancer patient can hear from their doctor is “recurrence.” Modern cancer therapies are a ...
JUL 04, 2020
Cancer
New mechanism that supports the progression and relapse cancer discovered
JUL 04, 2020
New mechanism that supports the progression and relapse cancer discovered
Researchers have found a mechanism of a key protein that supports the progression and relapse of cancer. This discovery ...
JUL 11, 2020
Cancer
New drug combo could improve immunotherapy for SCCOHT ovarian cancer
JUL 11, 2020
New drug combo could improve immunotherapy for SCCOHT ovarian cancer
Research published recently in PLOS ONE reports on SP-2577, a drug that could help girls and young women plagued with a ...
JUL 14, 2020
Drug Discovery & Development
How Cancer Cells Influence Drug Responses
JUL 14, 2020
How Cancer Cells Influence Drug Responses
When studying a large number of brain samples, researchers were able to characterize how changes in cells influence drug ...
Loading Comments...