AUG 25, 2015 11:26 PM PDT

Rising Second Cancers

“Second cancers are on the rise,” according to an article by Marilynn Marchione, AP medical writer, that appears in Bioscience Technology . “Nearly one in five new cases in the U.S. now involves someone who has had the disease before.”
Cancer cells: people getting a different kind of cancer for the second time may have the same mutations or environmental factors. 
Second cancers involve a different tissue type or a different site, not a recurrence or spread of the original tumor. One woman in suburban Philadelphia has had eight types of cancer over the last two decades, all treated successfully.
 
According to a recent study, about 19 percent of cancers in the United States now are second-or-more cases, as compared to 9 percent in the 1970s. During that period, the number of first cancers rose 70 percent, but the number of second cancers rose 300 percent. Some people consider this fact a partial success story: more people are surviving cancer and living long enough to get it again, because the risk of cancer rises with age.
 
The article explains that second cancers also can come from the same gene mutations or risk factors, such as smoking, that triggered the first instance. It also says that some of the treatments that enable people to survive their first cancer, such as radiation, can elevate the risk of getting a new cancer later in life, although treatments have “greatly improved in recent years to minimize this problem.”
 
Psychologically, the second cancer diagnosis can be more traumatizing than the first. Medically, they pose special challenges. Treatment choices could be more limited, because radiation is not usually applied to the same area of the body more than once. Certain drugs have lifetime dosage limits to avoid nerve or heart damage to the patient.
 
According to Dr. Alan Venook, a colon and liver cancer expert at the University of California, San Francisco, "The body has a memory for the radiation or chemotherapy" and can't endure too much of the same type. He explained that a second cancer means that doctors must assess genetic risk to the patient and possibly the family. "We've failed if a woman who had a BRCA1 mutation and had breast cancer develops colon cancer," he said. The gene mutation indicates that the patient should be monitored and screened often enough for other cancers to have any precancerous colon growths removed.
 
Experts have this advice for cancer survivors: have a formal survivorship plan, a blueprint for the future that includes a detailed summary of the treatment you received and what kind of monitoring is needed; don't neglect screenings for other forms of cancer besides the one you were treated for; get recommended tests such as colonoscopies, mammograms or HPV or Pap tests; and understand that treatments improve every day, and there are more resources for support.
About the Author
  • Ilene Schneider is the owner of Schneider the Writer, a firm that provides communications for health care, high technology and service enterprises. Her specialties include public relations, media relations, advertising, journalistic writing, editing, grant writing and corporate creativity consulting services. Prior to starting her own business in 1985, Ilene was editor of the Cleveland edition of TV Guide, associate editor of School Product News (Penton Publishing) and senior public relations representative at Beckman Instruments, Inc. She was profiled in a book, How to Open and Operate a Home-Based Writing Business and listed in Who's Who of American Women, Who's Who in Advertising and Who's Who in Media and Communications. She was the recipient of the Women in Communications, Inc. Clarion Award in advertising. A graduate of the University of Pennsylvania, Ilene and her family have lived in Irvine, California, since 1978.
You May Also Like
JUN 26, 2018
Cancer
JUN 26, 2018
Five "-omics" Fields Introduced
An introduction to genomics, transcriptomics, proteomics, epigenomics, and metabolomics....
JUN 27, 2018
Infographics
JUN 27, 2018
The Role of Biomarkers In Modern Medicine
A biomarker (short for biological marker) is a measurable indicator of some biological state or condition. The biomarker can be measured objectively and consistently. Biomarkers play signific...
JUL 10, 2018
Cancer
JUL 10, 2018
The ALFRED Analysis for Cancer Predisposition Genes
New proposed statistical method called ALFRED used to identify cancer predisposition genes....
AUG 14, 2018
Cancer
AUG 14, 2018
Using Arsenic to Enhance Cancer Therapies Beyond Leukemia
An already existing combination of arsenic and all-trans retinoic acid is found to inhibit a key signaling pathway that exerts broad effect on oncogenic processes for some solid tumors....
AUG 30, 2018
Genetics & Genomics
AUG 30, 2018
Genetic Changes can Help Diagnose Childhood Cancers Far Earlier
New research has revealed genetic rearrangements that happen far before bone cancer starts growing in children....
OCT 03, 2018
Cell & Molecular Biology
OCT 03, 2018
Single Cell Modified in CAR T Therapy Causes Deadly Relapse
One cell meant a very different outcome for a patient that was the recipient of a cutting-edge cancer therapy....
Loading Comments...