AUG 04, 2021 8:32 AM PDT

Can You Overdose on CBD?

WRITTEN BY: Annie Lennon

Due to limitations to research on cannabidiol (CBD), it can be hard to know which dose is best for you. While there are recommended doses, a lot of dosing ends up being ‘trial and error’. That said, can you overdose on CBD? And if you do, what happens? 

CBD is a nonpsychoactive compound of cannabis. It is known for its anti-inflammatory, antinausea, and antipsychotic effects, and is thus being explored in various clinical trials for potential use against different illnesses. While widely available as a supplement, however, CBD is still not approved or regulated by the US Food and Drug Administration, meaning dose recommendations may have limited validity. 

study from 2011 found that chronic use and high doses of CBD up to 1500 mg per day are well-tolerated. To put that in perspective, a one-ounce bottle of CBD oil can contain anything from 300 to 1,500 mg of CBD. How exactly this dosage may affect different individuals though, may depend on any underlying medical conditions, other medications being used, and route of administration. 

Some people may nevertheless experience negative side effects after taking high doses of CBD. In one case study from 2020, for example, a 56-year-old man consumed two packets of CBD gummies, or a total of 370 mg of CBD. Afterward, his speech began to slur, and he started vomiting. He was treated in hospital with intravenous fluids, oxygen, and antiemetics for vomiting and recovered the following day. 

While more research is needed to confirm possible side effects of excessive CBD consumption, some early studies have signaled that it may have adverse effects on respiratory, cardiovascular, reproductive, and cellular health. Others, however, show that when taken at smaller doses, CBD may have protective effects in the cardiovascular system and on lung function

To conclude, although CBD can be tolerated by many in higher doses, due to limitations in research, little is known on exactly what may happen if too much is taken. Until then, it is better to consult with a doctor to understand which dose is best for you to prevent any potential negative side effects. 

 

Sources: Curr Drug Saf.Cureus.Curr Neuropharmacol.Br J Clin PharmacolImmunopharmacol Immunotoxicol.

About the Author
  • Annie Lennon is a writer whose work also appears in Medical News Today, Psych Central, Psychology Today, and other outlets. When she's not writing, she is COO of Xeurix, an HR startup that assesses jobfit from gamified workplace simulations.
You May Also Like
APR 28, 2021
Health & Medicine
Adolescent Cannabis - No Long Term Cognitive Effects, But Still an Impact
APR 28, 2021
Adolescent Cannabis - No Long Term Cognitive Effects, But Still an Impact
An ongoing study that observes the cognitive, mental health and socioeconomic outcomes of twins has come to the conclusi ...
APR 30, 2021
Health & Medicine
Screen Over-50s for Cannabis Use, Say Researchers
APR 30, 2021
Screen Over-50s for Cannabis Use, Say Researchers
Nearly one in 10 individuals older than age 50 used cannabis in the past year, with nearly one in five reporting medical ...
MAY 06, 2021
Cannabis Sciences
New CBD Analog Outperforms Regular CBD for Pain Relief
MAY 06, 2021
New CBD Analog Outperforms Regular CBD for Pain Relief
Researchers from Temple University Health System have found that a novel cannabidiol (CBD) analog can reverse pain sensi ...
JUN 22, 2021
Cannabis Sciences
Report Finds Most First-Time Cannabis Users are Women
JUN 22, 2021
Report Finds Most First-Time Cannabis Users are Women
Chicago-based cannabidiol (CBD) and cannabis-focused market research organization, Brightfield Group, has published a ne ...
SEP 09, 2021
Health & Medicine
Cannabis and Pain Management- A Double Edged Sword?
SEP 09, 2021
Cannabis and Pain Management- A Double Edged Sword?
In 2016 it was estimated by the CDC that 20.4% of Americans have chronic pain. Chronic pain is a primary reaso ...
SEP 16, 2021
Cannabis Sciences
Cannabis Use and Exercise- A Dire Need for High-quality Evidence
SEP 16, 2021
Cannabis Use and Exercise- A Dire Need for High-quality Evidence
It should come as no surprise that exercise is good for our health. Regular exercise reduces the risks of serious chroni ...
Loading Comments...