JUN 22, 2017 3:39 PM PDT

Ultrasound "Drill" Dissolves Deep Blood Clots with Impeccable Precision

WRITTEN BY: Kara Marker

Dissolving clots deep in the veins has never been easier, thanks to new technology stemming from a collaboration between North Carolina State University and the University of North Carolina at Chapel Hill. Their new ultrasound “drill” dissolves blood clots with better aim than previous approaches.

An embolism traveling through a blood vessel.

Deep vein thrombosis (DVT) is a blood clot in a deep vein, usually the lower leg or thigh. This condition is dangerous because the blood clots can become un-lodged in the vessel, traveling as an embolus through the vasculature to the lungs and block the flow of blood, a condition called pulmonary embolism.

The new ultrasound technology dissolve blood clots better than two existing technologies. One relies on lateral emission of ultrasound waves, but damage done is not limited to blood clots; blood vessels are caught in the crossfire. This technique breaks clots into small pieces to prevent the excessive prescription of blood-thinning drugs, as large doses can have adverse side effects.

Another method, the “diamond-tipped drill technique” dissolves blood clots by “chewing” through them. This approach reduces the damage done to nearby blood vessels but results in larger pieces of broken-up blood clot, increasing the need for blood-thinning drugs.

The new technology improves upon the limitations of both of these existing methods. "Our new ultrasound tool is forward-facing, like a drill, but still breaks down clots into very fine particles," explained corresponding author from N.C. State, Xiaoning Jiang, PhD. "Our approach improves accuracy without relying on high doses of blood thinners, which we hope will reduce risks across the board."

The device works via a low-frequency intravascular ultrasound that breaks up blood clots that lead to DVT. An injection tube for microbubbles at the clot site dissolves the clot with extreme precision, reducing damage done to the blood vessel and reducing the amount of time it takes to complete the treatment. Jiang and his team recently tested the ultrasound method in synthetic blood vessels using cow’s blood.

“We could dissolve 90 percent of a clot in 3.5 to 4 hours without using any blood thinners at all," described lead author Jinwook Kim. "That's compared to 10 hours for the combination of conventional ultrasound tools and blood thinners."

The next step is testing in animal models. The researchers have filed a patent, and now they seek industry partners to develop the device.

The recent study was published in the journal Scientific Reports.

Sources: National Heart, Lung, and Blood Institute, North Carolina State University

About the Author
  • I am a scientific journalist and enthusiast, especially in the realm of biomedicine. I am passionate about conveying the truth in scientific phenomena and subsequently improving health and public awareness. Sometimes scientific research needs a translator to effectively communicate the scientific jargon present in significant findings. I plan to be that translating communicator, and I hope to decrease the spread of misrepresented scientific phenomena! Check out my science blog: ScienceKara.com.
You May Also Like
JUN 19, 2019
Genetics & Genomics
JUN 19, 2019
Genetic Link to Heart Disease is Stronger Than Thought
Previous work did not look at the impact of small changes in regulatory genes....
JUL 07, 2019
Cell & Molecular Biology
JUL 07, 2019
Directing Stem Cells to the Heart
Damaged tissue, such as heart cells that have died during a heart attack, could be repaired with stem cells if they are applied in the right way....
OCT 04, 2019
Cardiology
OCT 04, 2019
Heart Attacks Without The Risk
Following a heart attack, as the heart heals, scar tissue forms. This issue is less flexible than healthy heart tissue and may encumber the heart's abi...
NOV 07, 2019
Clinical & Molecular DX
NOV 07, 2019
A Revealing Look at Rare Disease Incidence
Being diagnosed with a rare disease can be especially terrifying for patients. After all, many of these diseases have no treatment options. This is because...
JAN 17, 2020
Cardiology
JAN 17, 2020
Toxic Metals and Cardiovascular Risk
A meta-analysis was recently published in the British Medical Journal to try and understand if there was a link between heart events and exposure to toxic ...
FEB 07, 2020
Cardiology
FEB 07, 2020
Eating Red and Processed Meats Increases Heart Disease Risk
Although the link between consuming processed meats and an increased risk of cardiovascular disease (CVD) is well established, studies focusing on the link...
Loading Comments...