MAR 16, 2017 5:29 PM PDT

Depression Has a Deadly Influence on Heart Disease

WRITTEN BY: Carmen Leitch

Researchers at the Intermountain Medical Center Heart Institute in Salt Lake City have determined that depression is the strongest predictor that death will occur in the first decade after a heart disease diagnosis. The study will be presented at the 66th Annual Scientific Session of the American College of Cardiology in Washington, D.C.; it found patients with coronary heart disease who also experience depression are roughly twice as likely to die when compared with heart disease patients who are not diagnosed with depression.

"Our study shows that it doesn't matter if depression emerges in the short term or a few years down the road - it's a risk factor that continually needs to be assessed," said the lead author of the report, Heidi May, PhD, MSPH, a cardiovascular epidemiologist at the Intermountain Medical Center Heart Institute in Salt Lake City. "I think the take-home message is that patients with coronary disease need to be continuously screened for depression, and if found to be depressed, they need to receive adequate treatment and continued follow-up."

The researchers focused on patients diagnosed with stable angina or unstable angina, or heart attack. All of those conditions result from an impaired flow of blood carrying oxygen to the heart, which usually happens because plaque builds up in the arteries of the heart. Coronary heart disease is an umbrella term for these disorders, when taken together they are the most common form of heart disease, responsible for the deaths of around 370,000 people in the U.S. every year.

It's known that heart disease and depression are linked together, with both increasing the likelihood of the other. This study has shown how devastating the long term impacts of this relationship are. "The majority of studies evaluating depression following a heart disease event have occurred within 30 days of the event," said May. "We sought to determine if the risk of all-cause mortality associated with depression varies with time between the diagnosis of heart disease and a follow-up depression diagnosis."

This work encompasses 25,000 patients that were followed for an average of ten years after coronary heart disease diagnosis. About 15 percent of patients were subsequently diagnosed with depression (a larger segment when compared to the general population, which experiences depression at a rate of seven to ten percent).

3,646 people in the study had a follow-up diagnosis of depression; half of those patients died while the study was ongoing. In the 20,491 people that did not receive A diagnosis of depression, 38 percent died. The bottom line: after a heart disease diagnosis, people that were depressed were twice as likely to die compared to those that were not.

May was surprised by the findings. "I thought depression would be significant, but not the most significant predictor," she added.

The researchers confirmed the data after correcting for other diseases, age, gender, risk factors, medications, heart attack or chest pain, and follow-up complications. Depression remained the strongest predictor of death in this group of patients. The researchers suggested that clinicians use these findings, and should seek to identify depression in heart disease patients, and help them deal with it.

"It can be devastating to be diagnosed with coronary artery disease. Clinicians need to pay attention to the things their patients are expressing, in terms of both physical symptoms as well as emotional and nonverbal factors," explained May. 

Depression includes a variety of symptoms including difficulty sleeping, feelings of hopelessness, anxiety, a loss of interest in hobbies, among other things. It is also associated with behaviors that are bad for cardiovascular health like a poor diet, reduced physical activity, increasing use of tobacco and alcohol, and poor compliance with medical treatment. Learn more about it in the video above.

"There is a lot more research that needs to be done with depression and heart disease. Moving forward, we would like to further assess treatment affects, severity of symptoms, and other comorbidities that may put a patient at an increased risk of death," May concluded. 

This work will be presented at the American College of Cardiology's 66th Annual Scientific Session in Washington, D.C. 

 

Sources: AAAS/Eurekalert! via Intermountain Health Care

About the Author
  • Experienced research scientist and technical expert with authorships on over 30 peer-reviewed publications, traveler to over 70 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
APR 27, 2021
Cardiology
New miRNAs Might Help Diagnose Severe Dilated Cardiomyopathy
APR 27, 2021
New miRNAs Might Help Diagnose Severe Dilated Cardiomyopathy
The heart is one of the most reliable parts of the body. It pumps day and night, delivering fresh oxygen and nutrients t ...
JUN 16, 2021
Clinical & Molecular DX
Rapid Screening Tool Provides Insights on Brain Health
JUN 16, 2021
Rapid Screening Tool Provides Insights on Brain Health
Scientists at King’s College London have identified a single biomarker that can be used to diagnose a range of neu ...
JUL 13, 2021
Clinical & Molecular DX
Friend or Foe? New Cancer-Tracking Pen Guides Surgeons.
JUL 13, 2021
Friend or Foe? New Cancer-Tracking Pen Guides Surgeons.
Researchers have developed the first diagnostic “pen” that acts as a guide for surgeons, helping them distin ...
JUL 15, 2021
Technology
Raman Spectroscopy Helps Track IBD Patient Response to Treatment
JUL 15, 2021
Raman Spectroscopy Helps Track IBD Patient Response to Treatment
While there have been multiple methods of evaluating whether a patient with inflammatory bowel disease (IBD) is respondi ...
AUG 05, 2021
Clinical & Molecular DX
Wearable Patch Senses Blood Vessel Blockages
AUG 05, 2021
Wearable Patch Senses Blood Vessel Blockages
The cardiovascular system is like a network of highways, filled with an estimated 25 trillion red blood cells that conti ...
SEP 07, 2021
Clinical & Molecular DX
Dogs Can Pick Up the 'Seizure Smell', Alert Their Owners
SEP 07, 2021
Dogs Can Pick Up the 'Seizure Smell', Alert Their Owners
Dogs offer so much more than companionship and unconditional love. New research shows that for patients with epilepsy, t ...
Loading Comments...