JUN 03, 2017 9:17 AM PDT

Beyond Broken Hips, CT Scans Predict Survival


A CT scan can do more than just reveal broken bones. In a new study, researchers found that CT scans can provide a glimpse into a patient’s overall muscle health, as well as predict survival following hip fractures.

Image Credit: Boutin Lab

Computed tomography (CT) scans combine a series of X-ray images taken at multiple angles to create a cross-sectional image of the body. This technology is widely used to diagnose bone and muscle conditions, and to detect bleeding and cancer.

But more than broken bones, the CT images reveal the health of the surrounding muscles. In particular, the scans give away the density of the “core” muscles that stabilize the spine. Those with lower core muscle size and density are more likely to be more frail, and therefore, have worse outcomes than patients whose core muscles are in better shape.

This knowledge is tremendously important when talking about the elderly population. "As patients age, it becomes increasingly important to identify the safest and most beneficial orthopaedic treatments, but there currently is no objective way to do this," said Robert Boutin, a UC Davis professor of radiology, and the study’s lead author.

Together with his colleagues, Boutin studied 300 elderly patients, aged 65 and older, who were treated for fall-related injuries between 2005 and 2015 at the UC Davis Medical Center. These patients all received CT scans to confirm or rule out hip fractures. Boutin then compared the images with mortality data from the National Death Index.

They found that not only can muscle information from CT scans predict the outcome of the treatment, the information also predicted survival. People who showed better core muscles had better survival rates than those with poor core muscles.

"Using CT scans to evaluate muscles in addition to hip bones can help predict longevity and personalize treatment to a patient's needs. We're excited because information on muscle is included on every routine CT scan of the chest, abdomen and pelvis, so the additional evaluations can be done without the costs of additional tests, equipment or software,” said Boutin.

This is the first study to link CT scans of hip fractures with survival in a non-cancer population. "The fact that we were able to predict survival in such a small group of non-cancer patients is truly remarkable," said Lenchik, professor of radiology at Wake Forest, and the study’s senior author.

"Recognizing sarcopenia [muscle loss] as a distinct condition that provides clues to future health can open doors to new discoveries in diagnosis and treatment," Boutin said. The team hopes such results will be leveraged to provide better treatment options for patients.

Additional source: UC Davis Medical Center



About the Author
  • I am a human geneticist, passionate about telling stories to make science more engaging and approachable. Find more of my writing at the Hopkins BioMedical Odyssey blog and at TheGeneTwist.com.
You May Also Like
AUG 13, 2019
Health & Medicine
AUG 13, 2019
Blood-Brain Barrier Impairment and Its Role in Alzheimer's Disease
In healthy people, the blood-brain barrier (BBB), which is fromed by brain endothelial cells, strictly controls the entrance of harmful materials into...
OCT 10, 2019
OCT 10, 2019
Parkinson's Disease is Present in the Blood
Parkinson's disease is a progressive disorder of the nervous system. Often starting with a barely noticeable tremor in one hand, the disease affects a...
OCT 16, 2019
Genetics & Genomics
OCT 16, 2019
A 'Molecular Clock' for Determining a Child's Age
This tool can aid in the diagnosis of developmental disorders, including autism spectrum disorder....
OCT 18, 2019
Health & Medicine
OCT 18, 2019
Are Washing Machines a Reservoir for Multidrug Resistant Pathogens?
Multidrug-resistant bacteria are frequently found in hospitals and long-term nursing facilities causing one of the largest public health concerns worldwide...
NOV 07, 2019
NOV 07, 2019
Reading, Hearing Language Connects Meaning to Same Region in the Brain
Scientists at the University of California Berkeley used improved functional MRI resolution to show that similar neural circuits in the same regions of the...
FEB 19, 2020
FEB 19, 2020
Testing the Immune Response to Ovarian Cancer Treatment
There is a new diagnostic test for the deadliest form of gynecological cancer – ovarian cancer. Better tests mean better diagnostics, and better diag...
Loading Comments...