MAY 08, 2020 7:31 AM PDT

Cholesterol Drugs May Boost Healthy Gut Bacteria in Obese People

WRITTEN BY: Annie Lennon

While statins have long been known for their efficacy in treating high cholesterol, until recently, there was no evidence on its benefits for the microbiome. Now though, tesearchers have found that obese people who take cholesterol-lowering statin drugs may be more likely to have healthier gut bacteria than those who don’t.

For their study, researchers from the Flanders Institute for Biotechnology in Belgium used data from the European Union study called MetaCardis to explore the link between cardiovascular disease and gut bacteria. The research project is known for having microbiome data from over 2,000 individuals from Europe across 1,400 variables including medication and body-mass index. 

From the 888 samples studied, they found that those with higher levels of Bacteroides 2 (Bact2) enterotype (a certain microbiome configuration) tended to have a higher body-mass index and a higher liklihood of being obese. This is particularly noteworthy as the Bact2 enterotype is associated with inflammation. Previous studies have shown that while 75% of people with inflammatory bowel disease have the enterotype, just 15% of those without it have the condition. 

The researchers also found that the pattern of enterotypes in obese people taking statins significnatly differed from those who do not take the drug. While just 5.9% of those taking statins had the Bact2 entereotype, 17.7% of those not taking the drug had the Pact 2 microbiome configuration. These results were repeated when analyzing data from the Flemish Gut Flora Project. 

The authors of the study caution that although their findings open an interesting avenue for further research, they should not be taken conclusively. When calculating their results, lifestyle and socioeconomic factors for example were not taken into account. More than this, due to the lack of ethnic diversity in their samples, these results may not apply for different ethnic groups. 

 

Sources: Forbes, Nature

 

About the Author
  • Science writer with keen interests in technology and behavioral biology. Her current focus is on the interplay between these fields to create meaningful interactions, applications and environments.
You May Also Like
AUG 11, 2020
Drug Discovery & Development
Scientists Discover Key Gene Behind Antibiotic Resistance
AUG 11, 2020
Scientists Discover Key Gene Behind Antibiotic Resistance
Scientists from Oxford University have shown that a single gene can make some strains of Staphylococcus aureus (the bact ...
AUG 24, 2020
Immunology
Injectable Drug Stops HIV From Entering Cells
AUG 24, 2020
Injectable Drug Stops HIV From Entering Cells
Once in the body, HIV tracks down T cells that bear the CD4 receptor. It attaches to these immune cells, fusing itself w ...
AUG 24, 2020
Cell & Molecular Biology
A Shield Surrounds the Flexible SARS-CoV-2 Spike Protein
AUG 24, 2020
A Shield Surrounds the Flexible SARS-CoV-2 Spike Protein
Researchers know that the viruses including SARS-CoV-2 have a Spike protein that allows them to bind to receptors on hos ...
AUG 17, 2020
Drug Discovery & Development
Therapy Found in The Shell of Cashews
AUG 17, 2020
Therapy Found in The Shell of Cashews
A compound found in the shell of cashews can help in neurodegeneration. "We see this as an exciting finding, sugges ...
SEP 09, 2020
Drug Discovery & Development
New Achondroplasia Treatment
SEP 09, 2020
New Achondroplasia Treatment
A recent clinical trial study found that an experimental drug, known as vosoritide, can be a potential treatment for ach ...
SEP 19, 2020
Drug Discovery & Development
Novel Drug Delivery System for Neurological Diseases
SEP 19, 2020
Novel Drug Delivery System for Neurological Diseases
Scientists at Rutgers have developed a smart drug delivery system that targets inflammation in damaged nerves and helps ...
Loading Comments...