JUN 07, 2020 8:42 PM PDT

Repurposing An Antibiotic To Defeat a Deadly Superbug

WRITTEN BY: Nouran Amin

A recent study published in Nature Microbiology describes how an old antibiotic used for Tuberculosis can be powerful treatment for a deadly superbug. The re-purposed antibiotic is Rifabutin and was shown to be powerfully active in fighting the multidrug-resistant Acinetobacter baumannii. The particular bacterium has been known to cause life-threatening emergencies according to study experts.

Learn more about the bacterium:

"Rifabutin has been around for more than 35 years, and no one has ever studied it for Acinetobacter infections before," said first author Brian Luna, assistant professor of molecular microbiology and immunology at Keck School of Medicine of USC. "Going forward, we may find many new antibiotics that have been missed over the last 80 years because the screening tests used to discover them were suboptimal."

According to the World Health Organization, Rifabutin is an ‘essential’ medicine and was heavily used for treating TB amongst HIV/AIDS populations who could not receive rifampin.

"Rifabutin can be used immediately to treat such infections because it is already FDA-approved, cheap and generic, and on the market," adds Brad Spellberg, the chief medical officer at the Los Angeles County-University of Southern California Medical Center and senior author of the study. "But we would like to see randomized controlled human trials to prove its efficacy, so we know for sure one way or the other."

Source: Science Daily

 

About the Author
  • Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
FEB 26, 2021
Microbiology
Good Bacteria Fights Bad Bacteria in a Clinical Trial
FEB 26, 2021
Good Bacteria Fights Bad Bacteria in a Clinical Trial
Eczema is a skin condition that causes a chronic, itchy rash. The most common form of the disorder, atopic dermatitis, i ...
APR 17, 2021
Drug Discovery & Development
Facebook AI May Speed up Cancer Drug Discovery
APR 17, 2021
Facebook AI May Speed up Cancer Drug Discovery
Facebook has claimed that its new artificial intelligence, known as 'Compositional Perturbation Autoencoder' (CP ...
MAY 04, 2021
Health & Medicine
Micro-dosing Inhaler Breakthrough for Medical Cannabis
MAY 04, 2021
Micro-dosing Inhaler Breakthrough for Medical Cannabis
In a leap that will eliminate the risks of vaping or smoking, Canada has just approved an Israeli-made inhaler that is a ...
MAY 12, 2021
Cardiology
Reversing the Heart Damage Seen in Marfan Syndrome
MAY 12, 2021
Reversing the Heart Damage Seen in Marfan Syndrome
Marfan syndrome is a genetic disorder that disrupts the connective tissues that anchor and link the body's organs, affec ...
JUN 01, 2021
Immunology
Nanoparticles Designed to Enhance Seasonal Flu Vaccines
JUN 01, 2021
Nanoparticles Designed to Enhance Seasonal Flu Vaccines
Seasonal flu vaccines only work around 40 to 60 percent of the time, says the U.S. Centers for Disease Control and Preve ...
JUN 01, 2021
Cannabis Sciences
Can Cannabis Help Manage Symptoms of Multiple Sclerosis?
JUN 01, 2021
Can Cannabis Help Manage Symptoms of Multiple Sclerosis?
As laws around cannabinoids continue to evolve, some people with chronic illnesses such as multiple sclerosis (MS), are ...
Loading Comments...