SEP 22, 2020 8:30 PM PDT

New Treatment for Mouth-Hand-Foot Disease

WRITTEN BY: Nouran Amin

A study appearing next week in the journal Nature Communications offers some good news in the search for antiviral drugs for hard-to-treat diseases. The enterovirus 71 is a common cause of hand, foot, and mouth disease in infants and young children. Now, scientists have discovered a potential therapeutic that can target the virus. The therapeutic is a small molecule that binds to the RNA of the virus and changing its 3D shape in a way that stops the virus from propogating and leading on the infection.

"For diseases that don't have good treatments, maybe the problem is we've been targeting the wrong thing," said co-author Amanda Hargrove, associate professor of chemistry at Duke.

Learn more about enteroviruses:

There are currently no FDA-approved drugs or vaccines for the enterovirus. The study could pave the way for an new antiviral treatment. Earlier studies found that a region of the RNA in the enterovirus folds over on itself where unpaired nucleotides balloon out. The present study is looking into targeting that area that allows the virus to spread.

Source: Science Daily

About the Author
BS/MS
Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
AUG 11, 2022
Cannabis Sciences
High Doses of CBD Safe for Driving
AUG 11, 2022
High Doses of CBD Safe for Driving
The University of Sydney research team studied the effects of cannabidiol (CBD) on driving, and they found that the high ...
AUG 16, 2022
Neuroscience
Fighting Cognitive Decline
AUG 16, 2022
Fighting Cognitive Decline
Researchers examined genetic and life course factors that may contribute to a “cognitive reserve” that prote ...
SEP 04, 2022
Neuroscience
The Facts About Fentanyl & Its Impact on the Brain
SEP 04, 2022
The Facts About Fentanyl & Its Impact on the Brain
You've probably heard of fentanyl, an extremely powerful, synthetic opioid that is used as a sedative, and sometimes ...
SEP 19, 2022
Genetics & Genomics
CGP: Simplifying the path from tumor to treatment
SEP 19, 2022
CGP: Simplifying the path from tumor to treatment
The promise of NGS in personalized cancer care For years, next-generation sequencing (NGS) has enabled oncologists to id ...
SEP 07, 2022
Drug Discovery & Development
An Oral Insulin Pill is Getting Closer
SEP 07, 2022
An Oral Insulin Pill is Getting Closer
Diabetes is a chronic disease that requires constant monitoring. Patients have to check the level of sugar, or glucose i ...
SEP 15, 2022
Neuroscience
Food Insecurity Affects Brain Development
SEP 15, 2022
Food Insecurity Affects Brain Development
A recent study found that food insecurity affects brain development in mice. University of California Berkeley researche ...
Loading Comments...