DEC 21, 2020 5:57 PM PST

Drug Increases Vaccine Responses

WRITTEN BY: Nouran Amin

A drug was found to increase the effects of vaccine responses in older adults. The drug works by removing cellular debris in immune cells and increasing the protective effects of vaccines in older adults.

"Older adults are at high risk of being severely affected by infectious diseases, but unfortunately most vaccines in this age group are less efficient than in younger adults," explains lead author Ghada Alsaleh, a postdoctoral researcher at the Kennedy Institute of Rheumatology, University of Oxford, UK.

A drug that boosts the removal of cellular debris in immune cells may increase the protective effects of vaccines in older adults.

"Our work suggests that boosting autophagy during vaccination may help make vaccines more effective for older people," Alsaleh says.

Findings were published in eLife and shows how these approaches can address the current COVID-19 pandemic and the common influenza.

Learn more about vaccines:

"Our findings will inform vaccine trials in which autophagy-boosting agents, such as spermidine, are given in a controlled environment to older participants," concludes senior author Anna Katharina Simon, Professor of Immunology at the University of Oxford. "It will be interesting to see whether these agents can enhance vaccination efficiency and help protect older people from viral infections."

Source: Science Daily

About the Author
  • Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
FEB 16, 2021
Immunology
Hugs From Immune Cells Heal Muscle
FEB 16, 2021
Hugs From Immune Cells Heal Muscle
Australian researchers have discovered a regenerative factor produced by immune cells that drives the repair and regener ...
MAR 09, 2021
Drug Discovery & Development
Leprosy Drug Repurposed for Potential COVID19 Treatment
MAR 09, 2021
Leprosy Drug Repurposed for Potential COVID19 Treatment
New research published in Nature study shows that a drug for treating leprosy was repurposed to treat COVID19. The study ...
MAR 30, 2021
Cardiology
Looking at a Fertility Drug's Cardiac Safety
MAR 30, 2021
Looking at a Fertility Drug's Cardiac Safety
New drugs go through a long and arduous process before they can grace a doctor’s office. One of the last steps is ...
APR 05, 2021
Neuroscience
Could a Keto Diet Treat Alzheimer's Disease?
APR 05, 2021
Could a Keto Diet Treat Alzheimer's Disease?
  Researchers from Brigham Young University have found evidence that eating a ketogenic diet- which is a diet that ...
APR 14, 2021
Cancer
Cell Viability- Where to Begin?
APR 14, 2021
Cell Viability- Where to Begin?
Written By: Author As I pondered the title of this article, my thoughts immediately went back to a request by my Ph.D. a ...
MAY 04, 2021
Immunology
One Vaccine to Rule Them All
MAY 04, 2021
One Vaccine to Rule Them All
There are currently five variants of concern in the U.S., genetically distinct forms of the COVID-causing coronavirus th ...
Loading Comments...