DEC 25, 2020 7:38 PM PST

Class of Antibiotics May Target Resistant Bacteria

WRITTEN BY: Nouran Amin

Researchers found a new class of antibiotics for combatting antimicrobial resistance (AMR).

Learn more about antibiotic resistance:

"We took a creative, double-pronged strategy to develop new molecules that can kill difficult-to-treat infections while enhancing the natural host immune response," said Farokh Dotiwala, M.B.B.S., Ph.D., assistant professor in the Vaccine & Immunotherapy Center and lead author of the effort to identify a new generation of antimicrobials named dual-acting immuno-antibiotics (DAIAs).

Findings were published in Nature.

"We reasoned that harnessing the immune system to simultaneously attack bacteria on two different fronts makes it hard for them to develop resistance," said Dotiwala.

"Immune activation represents the second line of attack of the DAIA strategy," said Kumar Singh, Ph.D., Dotiwala lab postdoctoral fellow and first author of the study.

"We believe this innovative DAIA strategy may represent a potential landmark in the world's fight against AMR, creating a synergy between the direct killing ability of antibiotics and the natural power of the immune system," echoed Dotiwala.

Source: Science Daily

About the Author
  • Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
APR 15, 2021
Drug Discovery & Development
Magic Mushroom Therapy and Antidepressants Produce Similar Results
APR 15, 2021
Magic Mushroom Therapy and Antidepressants Produce Similar Results
In recent years, psilocybin (the psychoactive ingredient in 'magic mushrooms') has gained increasing amounts of ...
MAY 13, 2021
Health & Medicine
New Peptide Allows Cannabis to Fight Pain With Fewer Side Effects
MAY 13, 2021
New Peptide Allows Cannabis to Fight Pain With Fewer Side Effects
THC-rich cannabis is well known to bring relief for some chronic pain sufferers. But the downside, off putting for many ...
MAY 14, 2021
Health & Medicine
A National Standard THC Dose for Researchers is Here
MAY 14, 2021
A National Standard THC Dose for Researchers is Here
    Whatever your stance on cannabis, almost  everyone would agree that more, better quality, research sh ...
JUN 22, 2021
Neuroscience
Virtual Reality Game Provides Pain Relief for Children
JUN 22, 2021
Virtual Reality Game Provides Pain Relief for Children
Researchers led by Ohio State University have found that smartphone-based virtual reality (VR) games can relieve pain fr ...
JUL 08, 2021
Cancer
Activating p53 May Boost Efficacy of Cancer Immunotherapy
JUL 08, 2021
Activating p53 May Boost Efficacy of Cancer Immunotherapy
Pharmacological activation of the p53 protein in cancer cells leads to an anti-tumor immune response in lab tests. These ...
JUL 23, 2021
Cancer
New Drug Eradicates Breast Cancer Tumors in Days
JUL 23, 2021
New Drug Eradicates Breast Cancer Tumors in Days
A new drug can kill between 95 and 100% of cancer cells in mice with human estrogen-receptor-positive breast cancer. The ...
Loading Comments...