JAN 13, 2021 2:45 PM PST

Antibody Can Target Dengue Viral Proteins

WRITTEN BY: Nouran Amin

Researchers have found an antibody that can stop the spread of the dengue virus—a mosquito-borne pathogen that infects 50 to 100 million people a year. Some of the symptoms of the virus includes fever, vomiting, muscle aches. It may lead to serious illness requiring long-term hospitalization and even in some cases fatal.

The dengue virus utilizes a particle protein called Non-Structural Protein 1 (NS1) that latches on the protective cells of organs and weakening the natural protective barrier. This allows virus to infect cells causing the rupture of blood vessels.

Learn more about the dengue virus:

However, the research shows that the antibody referred to as 2B7 will physically block the activity of NS1. It is effective against all four strains of the dengue virus.

"Flaviviruses infect hundreds of millions of people a year, and tens of thousands die from the associated diseases," said Argonne's Bob Fischetti, group leader with the X-ray Sciences Division and life sciences advisor to the APS director. "Protein structures determined at the APS have played a critical role in the development of drugs and vaccines for several diseases, and these new results are key to the development of a potentially effective treatment against flaviviruses."

Source: Science Daily

About the Author
  • Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
JAN 27, 2021
Drug Discovery & Development
Do Vaccines Work Against New Covid Variants?
JAN 27, 2021
Do Vaccines Work Against New Covid Variants?
The SARS-CoV-2 virus is mutating faster than scientists previously thought. As such, pharmaceutical companies are now sc ...
MAR 18, 2021
Drug Discovery & Development
New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
MAR 18, 2021
New Cancer Immunotherapy Targets Genetic Alteration in All Cancers
Researchers have developed a prototype for a new kind of cancer immunotherapy. The therapy uses engineered T-cells to ta ...
MAR 12, 2021
Drug Discovery & Development
Drug Starves Melanoma Tumors
MAR 12, 2021
Drug Starves Melanoma Tumors
Scientists at Sanford Burnham Prebys Medical Discovery Institute have identified a drug candidate that blocks the uptake ...
APR 05, 2021
Drug Discovery & Development
Scientists Regenerate Missing Teeth in Mice
APR 05, 2021
Scientists Regenerate Missing Teeth in Mice
While most people have 32 teeth, around 1% of the population has more or fewer due to congenital reasons. Now, researche ...
MAY 11, 2021
Genetics & Genomics
Gene Therapy Trial for Severe Immune Disorder is Successful
MAY 11, 2021
Gene Therapy Trial for Severe Immune Disorder is Successful
Severe combined immunodeficiency (SCID), which virtually eliminates a patient's immune system, and severely affects thei ...
MAY 12, 2021
Cardiology
Reversing the Heart Damage Seen in Marfan Syndrome
MAY 12, 2021
Reversing the Heart Damage Seen in Marfan Syndrome
Marfan syndrome is a genetic disorder that disrupts the connective tissues that anchor and link the body's organs, affec ...
Loading Comments...