JAN 13, 2021 2:45 PM PST

Antibody Can Target Dengue Viral Proteins

WRITTEN BY: Nouran Amin

Researchers have found an antibody that can stop the spread of the dengue virus—a mosquito-borne pathogen that infects 50 to 100 million people a year. Some of the symptoms of the virus includes fever, vomiting, muscle aches. It may lead to serious illness requiring long-term hospitalization and even in some cases fatal.

The dengue virus utilizes a particle protein called Non-Structural Protein 1 (NS1) that latches on the protective cells of organs and weakening the natural protective barrier. This allows virus to infect cells causing the rupture of blood vessels.

Learn more about the dengue virus:

However, the research shows that the antibody referred to as 2B7 will physically block the activity of NS1. It is effective against all four strains of the dengue virus.

"Flaviviruses infect hundreds of millions of people a year, and tens of thousands die from the associated diseases," said Argonne's Bob Fischetti, group leader with the X-ray Sciences Division and life sciences advisor to the APS director. "Protein structures determined at the APS have played a critical role in the development of drugs and vaccines for several diseases, and these new results are key to the development of a potentially effective treatment against flaviviruses."

Source: Science Daily

About the Author
BS/MS
Nouran is a scientist, educator, and life-long learner with a passion for making science more communicable. When not busy in the lab isolating blood macrophages, she enjoys writing on various STEM topics.
You May Also Like
APR 19, 2022
Drug Discovery & Development
Repurposing an Alcoholism Drug to Treat Anxiety
APR 19, 2022
Repurposing an Alcoholism Drug to Treat Anxiety
Anxiety is the most common mental illness in the U.S. According to the National Institutes of Health, nearly a third of ...
APR 19, 2022
Health & Medicine
Pandemic Creates Opportunity to Study Rare Vaccine Side Effects
APR 19, 2022
Pandemic Creates Opportunity to Study Rare Vaccine Side Effects
The Global Vaccine Data Network (GVDN) is a project conceived over 10 years ago to study vaccine side effects. Back then ...
MAY 15, 2022
Microbiology
A Virus Was Used to Cure an Antibiotic-Resistant Lung Infection
MAY 15, 2022
A Virus Was Used to Cure an Antibiotic-Resistant Lung Infection
In a clinical first, reported in Cell, researchers used viruses that infect bacteria, called bacteriophages or phages fo ...
JUN 21, 2022
Cell & Molecular Biology
From sample collection straight to RT-qPCR
JUN 21, 2022
From sample collection straight to RT-qPCR
Skip the nucleic acid purification step in your cancer detection workflow. Learn more about how Thermo Fisher Scientific ...
JUN 06, 2022
Cannabis Sciences
Price and Convenience: Key Reasons Why People Continue to Buy Illegal Cannabis
JUN 06, 2022
Price and Convenience: Key Reasons Why People Continue to Buy Illegal Cannabis
A study published in the Journal of Studies on Alcohol and Drugs found that price and convenience are the two main reaso ...
JUN 10, 2022
Drug Discovery & Development
The consequences of inappropriate antibiotic prescriptions in children
JUN 10, 2022
The consequences of inappropriate antibiotic prescriptions in children
The discovery of antibiotics in the early 1900’s was one of the most important discoveries in medical history. The ...
Loading Comments...