JAN 16, 2021 8:41 PM PST

Alternative Pain-Relief Bio-patch

WRITTEN BY: Nouran Amin

Researchers develop a bio-compatible patch that releases non-opioid painkillers for days and potentially serving as a safe substitute to opioid-based medications. The polymer patch releases a drug that blocks the activity of enzyme COX-2 (cyclooxygenase-2,) responsible for driving pain and inflammation.

"We were making hernia meshes and different antimicrobial films," said Matthew Becker, the Hugo L. Blomquist professor chemistry at Duke, and last author on the paper. "We thought you could potentially put pain drugs or anesthetics in the film if you just sew it in as you're stitching the person up, then you wouldn't necessarily have to prescribe any opioids," Becker said.

Findings of the study appeared in the Journal of Controlled Release.

"Most polymers that are used in medicine swell, and everything comes out at once," Becker said. But this polymer erodes slowly, and its painkiller dose and longevity can be controlled simply by varying the surface area and thicknesses. "The film is about like a piece of paper."

"If you can get four or five days of pain control out of the patch and not have to take those other pain drugs, not only do you avoid some of the side effects and risks of addiction, you're concentrating therapy where you need it," Becker said.

Learn more about how pain relievers work:

https://www.youtube.com/watch?v=9mcuIc5O-DE

Source: Science Daily

About the Author
  • Nouran earned her BS and MS in Biology at IUPUI and currently shares her love of science by teaching. She enjoys writing on various topics as well including science & medicine, global health, and conservation biology. She hopes through her writing she can make science more engaging and communicable to the general public.
You May Also Like
NOV 26, 2020
Cannabis Sciences
Women More Likely than Men to Swap Prescription Medication for Cannabis
NOV 26, 2020
Women More Likely than Men to Swap Prescription Medication for Cannabis
The stigma around cannabis usage is fading as cannabis laws become increasingly lax. Now, researchers from DePaul Univer ...
NOV 25, 2020
Drug Discovery & Development
Improving Drug Dissolution
NOV 25, 2020
Improving Drug Dissolution
When you take your medicine, it travels through the bloodstream and releases its effects. When the drug dissolves too fa ...
DEC 20, 2020
Genetics & Genomics
A Repurposed Drug Can Treat a Genetic Disorder
DEC 20, 2020
A Repurposed Drug Can Treat a Genetic Disorder
Some researchers have sought to treat genetic diseases by correcting the mutation. But it may be possible to use another ...
DEC 27, 2020
Genetics & Genomics
Delivering DNA- & RNA-Based Therapies in a New Way
DEC 27, 2020
Delivering DNA- & RNA-Based Therapies in a New Way
Gene therapy holds tremendous promise for its potential to cure genetic diseases. We've also recently seen how critical ...
JAN 03, 2021
Drug Discovery & Development
How Psychedelic Salvinorin A Works in the Brain
JAN 03, 2021
How Psychedelic Salvinorin A Works in the Brain
Despite increasing interest in hallucinogens, the effects of Salvinorin A, a drug used in Native Mexican rituals, have r ...
FEB 10, 2021
Drug Discovery & Development
Snail Venom Treats Malaria
FEB 10, 2021
Snail Venom Treats Malaria
In a first-of-its-kind study, scientists from Florida Atlantic University's Schmidt College of Medicine in collabora ...
Loading Comments...