APR 21, 2022 1:00 PM PDT

No Link Between Antidepressants and Improved Quality of Life

WRITTEN BY: Annie Lennon

Those who use antidepressant medications have similar health-related quality of life to people who are depressed and who do not take the drugs. The corresponding study was published in PLoS One

While antidepressant medications show some efficacy for treating depression in the empirical literature, their effects on overall wellbeing and health-related quality of life are controversial. To understand more about their long-term effects, the researchers behind the present study compared quality of life ratings between people with depression who use antidepressants and those who do not. 

To do so, they examined data from the United States' Medical Expenditures Panel Survey. Between 2005 and 2016, the researchers noted that an average of 17.5 million adults were diagnosed with depression each year. Women made up 67.9% of diagnoses, and 60.5% of female diagnoses received antidepressant medications compared to 51.5% of males. Quality of life was measured via the SF-12 health-related quality of life survey. 

In the end, the researchers found that antidepressant use was linked to some improvement in health-related quality of life after two years of treatment. However, when compared to quality of life ratings among those who did not take antidepressants, the researchers noted that taking the drugs was neither associated with improved physical or mental quality of life measures. 

The researchers note that their results are limited as they were not able to analyze for subtypes or different severities of depression. They add that future studies should include non-pharmacological treatments for depression alongside antidepressants. 

"Although we still need our patients with depression to continue using their antidepressant medications, long-term studies evaluating the actual impact for pharmacological and non-pharmacological interventions on these patients' quality of life is needed," added the researchers. 

"With that being said, the role of cognitive and behavioral interventions on the long term-management of depression needs to be further evaluated in an effort to improve the ultimate goal of care for these patients; improving their overall quality of life," they concluded. 

 

Sources: Science DailyPLoS One

About the Author
University College London
Annie Lennon is a writer whose work also appears in Medical News Today, Psych Central, Psychology Today, and other outlets. When she's not writing, she is COO of Xeurix, an HR startup that assesses jobfit from gamified workplace simulations.
You May Also Like
APR 13, 2022
Microbiology
Creating a foundation for change: A tangible strategy to fight AMR
APR 13, 2022
Creating a foundation for change: A tangible strategy to fight AMR
Apply the learnings of COVID to AMR, says coalition Tackling the deadly spectre of antimicrobial resistance (AMR) requir ...
APR 20, 2022
Microbiology
Rapid AST: A key weapon in the fight against AMR
APR 20, 2022
Rapid AST: A key weapon in the fight against AMR
Despite the dire, well-documented risks of antimicrobial resistance (AMR), which threatens to kill 10 million people a y ...
APR 15, 2022
Drug Discovery & Development
First Drug for Sleep Apnea Shows Promise in Patients
APR 15, 2022
First Drug for Sleep Apnea Shows Promise in Patients
A new drug for sleep apnea could reduce breathing pauses during sleep by over 20 per hour. The corresponding study was p ...
APR 21, 2022
Drug Discovery & Development
Antidepressants and Anti-epileptics During Pregnancy May Affect Infant Brain Development
APR 21, 2022
Antidepressants and Anti-epileptics During Pregnancy May Affect Infant Brain Development
Fetal exposure to a mother's antiepileptic or antidepressant medication may affect infant brain development. The cor ...
MAY 23, 2022
Drug Discovery & Development
A Possible Therapy for Infantile Spasms
MAY 23, 2022
A Possible Therapy for Infantile Spasms
Researchers at Texas Children’s Hospital have identified a possible cause of infantile spasms (IS) as well as a po ...
JUN 06, 2022
Cannabis Sciences
Price and Convenience: Key Reasons Why People Continue to Buy Illegal Cannabis
JUN 06, 2022
Price and Convenience: Key Reasons Why People Continue to Buy Illegal Cannabis
A study published in the Journal of Studies on Alcohol and Drugs found that price and convenience are the two main reaso ...
Loading Comments...