MAR 04, 2016 02:34 PM PST

What puts children at a greater risk for allergies?

WRITTEN BY: Kara Marker
All food allergies are not created equal. In fact, researchers from the University of Southampton set out to prove just that. In a unique new study, and with 1140 pregnant women as participants, scientists showed both the prevalence of two different types of allergies and the different factors that increase the risk of developing these allergies.

If parents suspect their child might have a food hypersensitivity, they could request a blood test from their doctor to look for immunoglobulin E (IgE) in the blood. IgE is an antibody with connections to allergies reactions and some allergies are IgE-mediated, but some are not. Therefore, a negative IgE blood test wouldn’t completely clear a child of having an allergy.
 
The eight foods that account for 90% of food allergic reactions in the U.S.


“These tests are only useful for IgE mediated food reactions and therefore are not useful in diagnosing non IgE mediated food allergies,” explained senior research fellow Dr. Kate Grimshaw. “IgE mediated and non-IgE mediated should be considered as two separate conditions and treated accordingly.”

IgE-mediated allergies and non-IgE mediated allergies differ in a few different ways, the researchers found. They observed their 1140 participants throughout their pregnancies, and after each child’s birth until they were two years old. First, IgE-mediated allergies usually cause skin rashes, vomiting, or respiratory issues. However, they can also cause life-threatening reactions as well. In contrast, non-IgE mediated allergies usually consist of mild stomach irritation, occurring between four and 28 hours after ingesting the food. 

The scientists also found that these two different types of food hypersensitivities are associated with different risk factors. Egg and peanut allergies, most often occurring as IgE-mediated hypersensitivities, are worse when in conjunction with eczema or rhinitis.

“Possibly due to a certain gene defect that prevents the skin barrier from forming correctly, leading to possible exposure of the immune system to allergens,” Grimshaw explained.

On the other hand, milk allergies, usually non-IgE mediated, proved to be worse for children in household with pets. In addition, the scientists made a connection between non-IgE mediated allergies and the age at which mothers starting feeding their children solid food. 

Grimshaw, whose study was published in the journal Clinical and Translational Allergy, also had an explanation for this result. 

“Pet ownership may increase the likelihood of gut reactions to food, perhaps by altering the gut flora, which can affect how the digestive system works.”

Luckily, the scientists also observed that a healthy diet helps to reduce the severity of both types of allergies. This is likely due to the disease-preventing and immune-boosting characteristics of the nutrients in fruits and vegetables.

Scientists from the University of Southampton and others will continue to investigate childhood allergies, but for now, knowing the risks and remedies will help to lessen the severity of both types of hypersensitivities.
 

Source: University of Southampton
About the Author
  • I am a scientific journalist and enthusiast, especially in the realm of biomedicine. I am passionate about conveying the truth in scientific phenomena and subsequently improving health and public awareness. Sometimes scientific research needs a translator to effectively communicate the scientific jargon present in significant findings. I plan to be that translating communicator, and I hope to decrease the spread of misrepresented scientific phenomena! Check out my science blog: ScienceKara.com.
You May Also Like
MAY 24, 2018
Immunology
MAY 24, 2018
Isolating a Neurological Protein May Protect Against Inflammatory Disorders
Investigators from Osaka University have isolated a neurological protein involved in the activation of immune cells that normally protect against inflammat...
JUN 14, 2018
Health & Medicine
JUN 14, 2018
Beware of Hotel Room Germs
Recently the CDC came out with a study that showed nearly 1/3 of swimming-related illnesses from 2000-2014 could be traced back to pathogens found in hotel...
JUN 22, 2018
Health & Medicine
JUN 22, 2018
A New Test for Peanut Allergy: Better, Faster, Cheaper.
Scientists from the Medical Research Council (MRC) in the UK have come up with a test to detect peanut allergies and it’s safer, quicker and more acc...
JUL 04, 2018
Microbiology
JUL 04, 2018
Revealing How Gut Bacteria can Impact our Health
Our GI tract pays host to trillions of microbes, which have been shown to play a highly influential role in our health and well-being....
JUL 17, 2018
Videos
JUL 17, 2018
Encouraging Progress on HIV Vaccine
In the quest to find a vaccine against HIV which causes AIDS, most attempts have failed. The HIV epidemic began about 35 years ago and in that time only fi...
JUL 24, 2018
Videos
JUL 24, 2018
Measles are on the Move
Measles is a highly contagious disease that used to be common in young children. Due to the development of vaccines, however, it’s been almost eradic...
Loading Comments...