JUL 09, 2015 11:21 AM PDT

Stroke and Memory

"Accelerated and persistent declines in memory and thinking ability" lasting as long as 6 years after a stroke "at a rate much faster than normal brain aging" were among the findings of a recent study, as reported by one of the co-authors, Deborah Levine. Levine, who holds faculty appointments in internal medicine and neurology at University of Michigan, says that "stroke is associated with cognitive decline over the long term" in an article published in the Journal of the American Medical Association and reported in Futurity (http://www.futurity.org/stroke-memory-956062/?utm_source=feedly&utm_medium=webfeeds).
Steep and significant declines in memory and thinking are seen in stroke patients as long as six years later.
The findings point to the need for better long-term follow-up care for the nation's 7 million stroke survivors, including therapy to retain or even regain cognitive ability, the study says. Funded by the National Institute for Neurological Disorders and Stroke and the National Institute on Aging and using data from 23,572 Americans aged 45 years or older from the Reasons for Geographic and Racial Differences in Stroke (REGARDS) study, the new research also includes scientists from the University of Alabama at Birmingham and Indiana University.

According to the National Stroke Association, about one third of stroke survivors will develop memory problems. These memory problems can be so severe that they interfere with normal functioning and are then classified as dementia, which is more common in older stroke survivors (http://www.stroke.org/we-can-help/survivors/stroke-recovery/post-stroke-conditions/cognition/memory-loss).

While the participants had no history of cognitive impairment when they entered the study in the mid-2000s, they were tested in terms of their memory and thinking ability at the beginning of the study and at regular intervals afterwards. They were monitored two times per year for acute stroke events, and suspected strokes were confirmed by study physicians. During a period of 6 to 10 years, 515 of the participants had a stroke, and researchers compared their test results with the others in the study. The researchers had information on the ways in which stroke survivors' memory and thinking ability changed over time before the stroke, enabling them to separate the declines in brain function traced to aging from declines in brain function traced to stroke. The latter included "declines in global cognition, new learning and verbal memory early after stroke as well as accelerated and persistent declines in global cognition and thinking ability over the years after the event", the report says.

Levine concludes, "Stroke is common, costly, and disabling, and cognitive decline is a major cause of disability in stroke survivors. Yet cognitive decline after stroke has not received enough attention. We hope these findings will shine a spotlight on stroke survivors' long-term cognitive needs."
About the Author
  • Ilene Schneider is the owner of Schneider the Writer, a firm that provides communications for health care, high technology and service enterprises. Her specialties include public relations, media relations, advertising, journalistic writing, editing, grant writing and corporate creativity consulting services. Prior to starting her own business in 1985, Ilene was editor of the Cleveland edition of TV Guide, associate editor of School Product News (Penton Publishing) and senior public relations representative at Beckman Instruments, Inc. She was profiled in a book, How to Open and Operate a Home-Based Writing Business and listed in Who's Who of American Women, Who's Who in Advertising and Who's Who in Media and Communications. She was the recipient of the Women in Communications, Inc. Clarion Award in advertising. A graduate of the University of Pennsylvania, Ilene and her family have lived in Irvine, California, since 1978.
You May Also Like
NOV 16, 2018
Genetics & Genomics
NOV 16, 2018
Using Light to Control Organ Development
Optogenetics combined genetic engineering with optics to create a way to control cellular behaviors with light....
NOV 26, 2018
Clinical & Molecular DX
NOV 26, 2018
Yours truly, microglia
Microglia, found primarily in CNS plays a role in many disease progression, hence a review to see how it might come to be....
DEC 17, 2018
Genetics & Genomics
DEC 17, 2018
Autism Risk Increased by Mutations in Non-Coding Regions
People have been desperate to learn more about the potential causes of autism, and researchers have been making some progress in recent years....
JAN 07, 2019
Technology
JAN 07, 2019
Software Program Decodes Rodent Chatter
Scientists have long known that rats and mice are social animals, always chatting up something new. Curious about understanding what is communicated betwee...
JAN 09, 2019
Cell & Molecular Biology
JAN 09, 2019
New Findings on the Early Stages of Autism Spectrum Disorder
While the prevalence of autism spectrum disorder has grown, there is still a lot we don't know about what causes the disorder....
JAN 16, 2019
Cannabis Sciences
JAN 16, 2019
Effects of Low Cannabis Use in Teens on the Brain
A recent article published in the Journal of Neuroscience presents more data to suggest that marijuana use in adolescents is harmful to brain development a...
Loading Comments...