MAR 30, 2015 10:41 PM PDT

Body's Good Fat Tissue Communicates With Brain Through Sensory Nerves

WRITTEN BY: Ilene Schneider
Brown fat tissue, the body's "good fat," communicates with the brain through sensory nerves, possibly sharing information that is important for fighting human obesity, such as how much fat we have and how much fat we've lost, according to researchers at Georgia State University.
Talking Fat
The findings, published in the Journal of Neuroscience, help to describe the conversation that takes place between the brain and brown fat tissue while brown fat is generating heat.

Brown fat is considered "good fat" or "healthy fat" because it burns calories to help generate heat for our bodies and expend energy, while white fat stores energy for later and can increase the risk for health issues, such as diabetes and heart disease. A person with a healthy metabolism has less white fat and an active supply of brown fat.

Studies show that brown fat plays a big role in someone having the capability to burn more energy, becoming a tool to stay trim and fight obesity. Pharmaceutical companies are trying to target brown fat and activate it more, said Johnny Garretson, study author and doctoral student in the Neuroscience Institute and Center for Obesity Reversal at Georgia State.

The study found that when brown fat tissue was activated with a drug that mimics the sympathetic nervous system messages that normally come from the brain, the fat talked back to the brain by activating sensory nerves. The sensory nerves from brown fat increased their activity in response to direct chemical activation and heat generation.

"This is the first time that the function of sensory nerves from brown fat has been examined," Garretson said. "Brown fat is an active organ that's relatively important for metabolism, and we found a new pathway of its communication.

"The study informs us more about the communication between fat and the brain, which is really beneficial for treating human obesity. There is evidence that people with more brown fat have a better metabolism, lower instances of type II diabetes and are trimmer. Knowing how to increase the amount of brown fat activity or increase the brown fat, that's the future of trying to figure out yet another way to try and lose weight effectively and quickly."

The researchers speculate that brown fat is telling the brain many things, such as how much heat is being generated, how much and what types of free energy are being used or stored, how much fat we have and how much fat we've lost.

"As brown fat gets hotter and starts to generate heat, being active and doing good things for our body, it increases our metabolism and helps us burn white fat," Garretson said. "As it's getting hotter, Dr. (Vitaly) Ryu and other members of our lab found that it tells the brain it's getting hotter. We think this is some type of feedback, like a thermostat, and as it gets hotter, it probably controls how the brain is talking back to it."

It was already known the brain communicates with fat tissue by telling it to break down and either release or use free energy for our bodies to function. This study shows a feedback loop between brown fat tissue and the brain.

The research team has studied the communication from fat to the brain and the brain to fat for years, but they're one of only a few labs in the world to examine communication from fat to the brain through the nervous system, Garretson said.

Source: Georgia State University
About the Author
  • Ilene Schneider is the owner of Schneider the Writer, a firm that provides communications for health care, high technology and service enterprises. Her specialties include public relations, media relations, advertising, journalistic writing, editing, grant writing and corporate creativity consulting services. Prior to starting her own business in 1985, Ilene was editor of the Cleveland edition of TV Guide, associate editor of School Product News (Penton Publishing) and senior public relations representative at Beckman Instruments, Inc. She was profiled in a book, How to Open and Operate a Home-Based Writing Business and listed in Who's Who of American Women, Who's Who in Advertising and Who's Who in Media and Communications. She was the recipient of the Women in Communications, Inc. Clarion Award in advertising. A graduate of the University of Pennsylvania, Ilene and her family have lived in Irvine, California, since 1978.
You May Also Like
SEP 02, 2020
Clinical & Molecular DX
Feeling Tired? Scientists Use Brain Scans to Measure Fatigue
SEP 02, 2020
Feeling Tired? Scientists Use Brain Scans to Measure Fatigue
Yawning in the middle of the day is completely normal for people with hectic schedules. How do you know whether it&rsquo ...
SEP 24, 2020
Health & Medicine
Extreme Isolation can Cause Physical Brain Changes
SEP 24, 2020
Extreme Isolation can Cause Physical Brain Changes
By this point in the year, you’ve either heard or uttered the phrase “quarantine brain.” While the act ...
OCT 20, 2020
Neuroscience
Negative Behavior Triggers Same Brain Patterns as Bad Smells
OCT 20, 2020
Negative Behavior Triggers Same Brain Patterns as Bad Smells
Researchers from the University of Geneva have found that witnessing negative behaviors triggers similar neural response ...
OCT 21, 2020
Drug Discovery & Development
Experimental Vaccine Shows Promise in Halting Alzheimer's
OCT 21, 2020
Experimental Vaccine Shows Promise in Halting Alzheimer's
In a preclinical study, researchers from the Univerity of South Florida have found that a vaccine that targets neurotoxi ...
NOV 07, 2020
Neuroscience
Device Measures Stress Hormones with Earwax
NOV 07, 2020
Device Measures Stress Hormones with Earwax
Researchers from University College London and King’s College London in the UK have developed a device that can me ...
NOV 15, 2020
Neuroscience
Brain Chemical Noradrenaline Helps Us Adapt to Uncertainty
NOV 15, 2020
Brain Chemical Noradrenaline Helps Us Adapt to Uncertainty
Researchers from the University of Cambridge and University College London have found that a neurochemical known as nora ...
Loading Comments...