JUN 03, 2022 1:00 PM PDT

How Fish Developed Electric Organs and What it Means for Human Disease

WRITTEN BY: Ryan Vingum

A new study published in Science Advances explores the unique evolutionary processes among certain genes in certain fish species that allowed them to develop electric organs (think: the electric eel). But the findings from this study, conducted by researchers at the University of Texas at Austin, may also shed some light on the underlying genetic causes of certain human diseases.

Fish like the infamous electric eel are unique because they can, well, produce electricity from within their body. Part of the reason for this has to do with very small genetic changes that occured over millions of years to a very particular part of fish genetics: a duplicative gene that produces muscle motors, or sodium channels. Over time, this extra gene was turned off in specific muscles and turned on in other cells, which allowed fish to generate electric pulses in different areas of the body, leading to the development of organs capable of producing electricity. 

In studying electric fish, researchers noted that a specific section of the gene for sodium channels that determines whether it is expressed in a given cell is missing in electric fish. The research team noted that this control feature needed to be turned off so that the gene would only be expressed in the electric organ.

Researchers examined African and South American electric fish to learn about these genetic changes. They noted that while one species had mutations in the control gene and another was missing it altogether, both fish stil evolved an electric organ, just through different mechanisms. 

Interestingly, this specific section of the sodium channel-controlling gene is found in other vertebrates, including humans. The research team thinks this begs an important question: how does the expression of sodium channels in humans impact disease development?   

Researchers hope to better explore how these control sections of electric fish genetic code evolved to affect sodium channels in their newly developed electric organ. 

Sources: EurekaAlert!; Science Advances

 

About the Author
Professional Writing
Science writer and editor, with a focus on simplifying complex information about health, medicine, technology, and clinical drug development for a general audience.
You May Also Like
MAR 23, 2022
Plants & Animals
Using an Embalming Technique to Make Bamboo Fibers Stronger
MAR 23, 2022
Using an Embalming Technique to Make Bamboo Fibers Stronger
Plastination is an embalming process used to preserve bodies. The process involves dehydrating the body tissue and repla ...
MAR 30, 2022
Immunology
Killifish Research Model Shows Antibody Diversity Declines with Age
MAR 30, 2022
Killifish Research Model Shows Antibody Diversity Declines with Age
Shown in in this image (courtesy of Max Planck Institute for Biology of Ageing/CC BY-ND) the African killifish can be us ...
APR 27, 2022
Cannabis Sciences
Why Is Weed So Much Stronger Than It Used To Be?
APR 27, 2022
Why Is Weed So Much Stronger Than It Used To Be?
Weed is stronger these days than ever before. What's behind this development?
MAY 08, 2022
Microbiology
A Relative of Some of the World's Deadliest Viruses is Found in Europe
MAY 08, 2022
A Relative of Some of the World's Deadliest Viruses is Found in Europe
African fruit bats are the natural hosts of Marburg and Ebola viruses, both of which are filoviruses. These RNA viruses ...
MAY 24, 2022
Genetics & Genomics
The Oat Genome Reveals Why It's Good for the Gut
MAY 24, 2022
The Oat Genome Reveals Why It's Good for the Gut
You may have heard of haploid and diploid species, which carry one set of unpaired chromosomes, or two sets chromosomes, ...
JUN 25, 2022
Genetics & Genomics
Similar 'Jumping Genes' are Active in Human and Octopus Brains
JUN 25, 2022
Similar 'Jumping Genes' are Active in Human and Octopus Brains
Cephalopods, including octopuses, have exceptionally large and complex nervous systems; the octopod brain is thought to ...
Loading Comments...