MAR 18, 2017 03:29 PM PDT

Lipoprotein Study Could Lead to Changes in Heart Disease Diagnosis

WRITTEN BY: Carmen Leitch

Scientists at King's College London have measured the levels of lipoproteins, the components of cholesterol, in a population study. The findings, reported in the Journal of the American College of Cardiology, could lead to improvements in how early cardiovascular disease is diagnosed.

While the main portion of HDL cholesterol, considered to be good, is apoA1, and the main component of bad cholesterol or LDL is apoliprotein B, apoB, it seems that another group of lipoproteins altogether are better indicators of so-called good and bad cholesterol. The other group of apolipoproteins, apoE, apoC2 and apoC3, are connected to fat molecules called very low-density lipoproteins, VLDL, and another kind of fat called triglycerides. The work determined that apoE, apoC2 and apoC3 are more strongly associated with cardiovascular disease than apoA1 and apoB.

"We directly compared the association of a broad panel of apolipoproteins to new onset of cardiovascular disease over a 10-year observation period, and found that while apoB was predictive, other apolipoproteins, namely aopE, aopC2 and apoC3, were even better," said lead author of the report, Professor Manuel Mayr of King's College London. "These unexpected strong associations of VLDL-associated apolipoproteins with cardiovascular disease provide support to expanding the current measurements of apolipoproteins and to the concept of targeting additional apolipoproteins to reduce risk."
About the Author
  • Experienced research scientist and technical expert with authorships on 28 peer-reviewed publications, traveler to over 60 countries, published photographer and internationally-exhibited painter, volunteer trained in disaster-response, CPR and DV counseling.
You May Also Like
NOV 17, 2019
Plants & Animals
NOV 17, 2019
Watch a Pod of Dolphins Play Catch With a Pufferfish
Playing catch with a ball of some sort is a popular past time for humans, but as it would seem, even dolphins might enjoy partaking in similar behaviors. I...
NOV 17, 2019
Earth & The Environment
NOV 17, 2019
Yale Scientists Solve Mass Extinction Mystery
Scientists from Yale University have solved a mystery that has plagued scientists for decades. It’s well established that 66 million years ago, a mas...
NOV 17, 2019
Space & Astronomy
NOV 17, 2019
Here's What We Know So Far About Titan's Liquid Methane Oceans
Titan is perhaps one of the most captivating moons orbiting Saturn today; so much so that astronomers spent a lot of time studying it when the Cassini miss...
NOV 17, 2019
Space & Astronomy
NOV 17, 2019
How Much Do You Know About NASA's Voyager Missions?
NASA’s Voyager 1 and 2 spacecraft each launched in 1977 for a unique opportunity to explore the solar system’s outermost planets in unprecedent...
NOV 17, 2019
Space & Astronomy
NOV 17, 2019
Starlink Aims to Provide Cutting-Edge Worldwide Internet Access
Almost everyone has heard by now that Elon Musk wants to launch well over 40,000 new satellites into space to deliver high-speed and low-latency internet t...
NOV 17, 2019
Space & Astronomy
NOV 17, 2019
Did You Miss the Mercury Transit? Here's NASA's Footage
Monday was a particularly exciting day for amateur astronomers. It was the day that the planet Mercury performed a visible transit across the Sun’s s...
Loading Comments...