AUG 31, 2017 6:11 AM PDT

New Hope for Brain Cancer Patients


In children, brain cancer is the number one cause of cancer-related deaths. Brain tumors are extremely aggressive and often resistant to treatment since many drugs cannot pass through the blood brain barrier. At the Queensland Institute for Molecular Bioscience, researchers mapped the genes of medulloblastoma tumors to find out why they are so deadly and what, if anything, could be used to kill the cancer cells that take over so quickly. Once the genes responsible for the tumors lethal strength were identified, researchers looked for drugs that are already available that have been effective in shutting down those genetic expressions.

After the analysis of the genes involved in medulloblastoma, researchers predicted that Palbociclib, a drug approved for the treatment of ER-positive and HER2-negative breast cancer, could be effective. In clinical trials, the outcome was quite good with this drug. In some cases, medullablastoma tumor growth was shut down, and in a few, the tumors shrunk enough to allow for survival. The drug was only used for short time and produced these results. While there were some recurrences, likely to due to resistant cells in the brain tumors, the team believes that adding palbociclib to chemotherapy regimens could reduce recurrence as well.
About the Author
  • I'm a writer living in the Boston area. My interests include cancer research, cardiology and neuroscience. I want to be part of using the Internet and social media to educate professionals and patients in a collaborative environment.
You May Also Like
OCT 22, 2020
Chemistry & Physics
NASA Looks to Nuclear Fusion for Powering Deep Space Missions
OCT 22, 2020
NASA Looks to Nuclear Fusion for Powering Deep Space Missions
Nuclear fusion is the frontier of energy research, and NASA has a plan to bring this state-of-the-art power source to th ...
JAN 11, 2021
Immunology
Can Immune cells contribute to Lung Diseases Severity?!
JAN 11, 2021
Can Immune cells contribute to Lung Diseases Severity?!
Macrophages are a type of immune cell that can detect and destruct bacteria, viruses, and harmful materials. They a ...
MAR 03, 2021
Plants & Animals
Can Arctic Bearded Seals Compete with Human Noise?
MAR 03, 2021
Can Arctic Bearded Seals Compete with Human Noise?
Vocal communication is a primary key to survival for many species, including the Arctic Ocean's bearded seals. Accor ...
MAY 01, 2021
Space & Astronomy
Small Galaxies Played Key Role in Evolution of the Universe
MAY 01, 2021
Small Galaxies Played Key Role in Evolution of the Universe
Astrophysicists from the University of Minnesota have found evidence for the theory that small galaxies emitting high-en ...
MAY 30, 2021
Space & Astronomy
New Discovery Casts Origin of Milky Way into Doubt
MAY 30, 2021
New Discovery Casts Origin of Milky Way into Doubt
A detailed cross-section of another galaxy, known as YGC 10738, has cast previous ideas of how the Milky Way was formed ...
JUL 03, 2021
Space & Astronomy
Size of Planet Iron Core Depends on Star Magnetism
JUL 03, 2021
Size of Planet Iron Core Depends on Star Magnetism
Researchers led by the University of Maryland have found that the sun's magnetic field is the reason behind the larg ...
Loading Comments...