AUG 31, 2017 06:11 AM PDT

New Hope for Brain Cancer Patients


In children, brain cancer is the number one cause of cancer-related deaths. Brain tumors are extremely aggressive and often resistant to treatment since many drugs cannot pass through the blood brain barrier. At the Queensland Institute for Molecular Bioscience, researchers mapped the genes of medulloblastoma tumors to find out why they are so deadly and what, if anything, could be used to kill the cancer cells that take over so quickly. Once the genes responsible for the tumors lethal strength were identified, researchers looked for drugs that are already available that have been effective in shutting down those genetic expressions.

After the analysis of the genes involved in medulloblastoma, researchers predicted that Palbociclib, a drug approved for the treatment of ER-positive and HER2-negative breast cancer, could be effective. In clinical trials, the outcome was quite good with this drug. In some cases, medullablastoma tumor growth was shut down, and in a few, the tumors shrunk enough to allow for survival. The drug was only used for short time and produced these results. While there were some recurrences, likely to due to resistant cells in the brain tumors, the team believes that adding palbociclib to chemotherapy regimens could reduce recurrence as well.
About the Author
  • I'm a writer living in the Boston area. My interests include cancer research, cardiology and neuroscience. I want to be part of using the Internet and social media to educate professionals and patients in a collaborative environment.
You May Also Like
NOV 18, 2019
Plants & Animals
NOV 18, 2019
These Animals Give Birth to the Largest Babies in the World
Moms everywhere will tell you all about the excruciating labor pains that come along with delivering a baby, but in the animal kingdom, many newborns are s...
NOV 18, 2019
Earth & The Environment
NOV 18, 2019
Greenland's Summer Melt Helps Scientists Track Sea Level Rise
This summer, the Greenland Ice Sheet experienced a significant melting event not seen since 2002, mainly due to the heatwave that swept through most of Eur...
NOV 18, 2019
Earth & The Environment
NOV 18, 2019
Ready for Winter? NOAA's Winter Outlook is Here
Are you wondering what winter will look like in your region? Depending on where you live, you may be in for a mild season. Last week, the National Oceanic...
NOV 18, 2019
Cardiology
NOV 18, 2019
Protein Build-Up Places Heart at Risk
Amyloidosis is a disease caused by protein buildup in the body. These abnormal proteins, called amyloids, are produced in the bone marrow. Multiple types o...
NOV 18, 2019
Space & Astronomy
NOV 18, 2019
What You Need to Know About NASA's Upcoming WFIRST Space Telescope
There are several space telescopes observing the cosmos at the very time of this writing, and there are plans to launch even more of them in the near futur...
NOV 18, 2019
Plants & Animals
NOV 18, 2019
Triggerfish Are Lobsters' Worst Enemies
Lobsters, just like many other animals, follow migration patterns. They are often observed traveling in large packs, marching in straight lines across the...
Loading Comments...