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JUN 5, 2025

Sake & Science: Advances in Multiomics for Biomarker Discovery

Join us for a science symposium where cutting-edge biology meets transformative technology. Dive deep into molecular research using the latest multiomics advances, from the granularity of single-cell insights to the expansive power of spatial mapping and long-read sequencing.

While single-cell sequencing has revolutionized scientists’ ability to understand disease mechanisms by deconvoluting heterogeneity within organs and tissues, the rise of multiomics has empowered researchers to combine transcriptomic or epigenomic data with spatial data for an expanded, multidimensional understanding of complex tissue biology. Leveraging additional improvements in cell throughput, spatial resolution, and transcript coverage, current single-cell sequencing technologies have opened new avenues for molecular exploration into disease mechanisms, cellular heterogeneity, and new biomarker identification.

Whether you're a researcher or biotech innovator, this event will spark ideas, foster collaboration, and showcase technologies for in-depth biomarker exploration.

 

What to expect:

  • High-throughput single-cell multiomics—discover how integrated multiomic profiling is reshaping our understanding of cellular function and identity
  • Spatial transcriptomics—explore how combining gene expression data with cellular location in tissues unlocks context-specific biological patterns
  • Long-read sequencing—learn how sequencing of full-length transcripts overcomes the limitations of short-read technologies

This hybrid event will take place online and onsite at Takara Bio USA, Inc. in San Jose, CA.


Speakers
  • Dr. Patrick Cahan, Ph.D. (Virtual)

    Associate Professor, Johns Hopkins University
  • Dr. Gabriela Salinas, Ph.D. (Virtual)

    Head of Core Unit: NGS Integrative Genomics, University Medical Center Göttingen
    BIOGRAPHY
  • Dr. Matthew Jones, Ph.D. (Onsite, San Jose, CA)

    Postdoctoral Fellow, Stanford University
    BIOGRAPHY
  • Dr. Christina Fan, Ph.D. (Virtual; Onsite, San Jose, CA)

    Vice President, Spatial Genomics R&D, Takara Bio USA
    BIOGRAPHY
  • Farshad Farshidfar, MD., Ph.D. (Onsite, San Jose, CA)

    Senior Scientist, Tenaya Therapeutics
    BIOGRAPHY
  • Dr. Yue Yun, Ph.D. (Virtual; Onsite, San Jose, CA)

    Senior Director, NGS R&D, Takara Bio USA
    BIOGRAPHY
  • Dr. Linbo Zhao, Ph.D. (Onsite, San Jose, CA)

    Staff Scientist, Takara Bio USA
    BIOGRAPHY
  • Dr. Daniel Kim, Ph.D. (Onsite, San Jose, CA)

    Assistant Professor, University of California Santa Cruz
    BIOGRAPHY

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On Site Details

The in-person portion of the June 5th Sake & Science Seminar: Advances in Multiomics for Biomarker Discovery will be a rich and engaging experience. Attendees will be welcomed with small bites, and sake tasting to celebrate Takara’s century-long history in sake production while viewing scientific posters. The scientific program will feature presentations from leading researchers in the fields of single-cell analysis, spatial biology, and advanced multiomic technologies. Participants will also have the opportunity to discuss their research findings, engage with instrument demonstrations, and learn about early access programs.

Please plan to arrive at our San Jose headquarters by 12pm. We are offering attendees the option to take Caltrain to the Santa Clara station, where there will be an event shuttle to transport you to Takara Bio. If you would like to utilize this service, please let us know so we may coordinate your pickup. Alternatively, if you are thinking of driving, we have ample onsite parking.

Address:
Takara Bio USA, Headquarters
2560 Orchard Pkwy
San Jose, CA 95131

Agenda

Virtual Event Agenda:

10:00am - 12:00pm PT:

 

  • Dr. Patrick Cahan, Associate Professor, Johns Hopkins University
    • Decoding early synovial joint development with single-cell and spatial transcriptomics
  • Dr. Christina Fan, Vice President, Spatial Genomics R&D, Takara Bio USA 
    • Single-nuclei spatial tagging brings new solutions for spatial multiomic discoveries
  • Dr. Gabriela Salinas, Head of Core Unit NGS Integrative Genomics, University of Göttingen
    • Integrating multi-omics data from cardiac biopsies in heart failure
  • Dr. Yue Yun, Senior Director, NGS R&D, Takara Bio USA
    • Empowering discovery with automated total RNA and WGA sequencing

 

In-Person Agenda

12:00pm -4:00pm PT:

  • Arrival, Poster Session and small bites with sake tasting
  • Dr. Andrew Farmer, Chief Scientific Officer, Takara Bio USA
    • Welcome Remarks
  • Dr. Matt Jones, Postdoctoral Scholar, Stanford University
    • Tracing the spatiotemporal evolution of cancer
  • Dr. Christina Fan, Vice President, Spatial Genomics R&D, Takara Bio USA 
    • Single-nuclei spatial tagging brings new solutions for spatial multiomic discoveries

Break

  • Dr. Farshad Farshidfar, Senior Bioinformatics Scientist, Tenaya Therapeutics 
    • Cracking HFpEF: deep cellular signatures of dysfunction and recovery in failing hearts
  • Dr. Yue Yun, Senior Director, NGS R&D, Takara Bio USA
    • Empowering discovery with automated total RNA and WGA sequencing
  • Dr. Linbo Zhao, Staff Scientist, Takara Bio USA
    • Multiomic integration of transcriptome and genome analysis to enable novel biomarker discovery

Break

  • Dr. Daniel Kim, Assistant Professor, UC Santa Cruz 
    • Nanopore sequencing enables esophageal cancer early detection via RNA liquid biopsy
  • Panel Discussion
    • Advances in multiomics for biomarker discovery

 

Speakers


  • Dr. Patrick Cahan, Ph.D. (Virtual)

    Dr. Patrick Cahan, Ph.D. (Virtual)

    Associate Professor, Johns Hopkins University

  • Dr. Gabriela Salinas, Ph.D. (Virtual)

    Dr. Gabriela Salinas, Ph.D. (Virtual)

    Head of Core Unit: NGS Integrative Genomics, University Medical Center Göttingen

    BIOGRAPHY
  • Dr. Matthew Jones, Ph.D. (Onsite, San Jose, CA)

    Dr. Matthew Jones, Ph.D. (Onsite, San Jose, CA)

    Postdoctoral Fellow, Stanford University

    BIOGRAPHY
  • Dr. Christina Fan, Ph.D. (Virtual; Onsite, San Jose, CA)

    Dr. Christina Fan, Ph.D. (Virtual; Onsite, San Jose, CA)

    Vice President, Spatial Genomics R&D, Takara Bio USA

    BIOGRAPHY
  • Farshad Farshidfar, MD., Ph.D. (Onsite, San Jose, CA)

    Farshad Farshidfar, MD., Ph.D. (Onsite, San Jose, CA)

    Senior Scientist, Tenaya Therapeutics

    BIOGRAPHY
  • Dr. Yue Yun, Ph.D. (Virtual; Onsite, San Jose, CA)

    Dr. Yue Yun, Ph.D. (Virtual; Onsite, San Jose, CA)

    Senior Director, NGS R&D, Takara Bio USA

    BIOGRAPHY
  • Dr. Linbo Zhao, Ph.D. (Onsite, San Jose, CA)

    Dr. Linbo Zhao, Ph.D. (Onsite, San Jose, CA)

    Staff Scientist, Takara Bio USA

    BIOGRAPHY
  • Dr. Daniel Kim, Ph.D. (Onsite, San Jose, CA)

    Dr. Daniel Kim, Ph.D. (Onsite, San Jose, CA)

    Assistant Professor, University of California Santa Cruz

    BIOGRAPHY
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