3D Visualisation and Characterisation of Downstream Bioprocessing Structures to Inform Advanced Designs

High-resolution, 3D imaging enabled depth filters, chromatography columns and sterile filters to be analysed across multiple length scales. Generating a geometry-based database enabled structure to be related to function and performance has allowed for chemical and physical characteristics required for optimal separation to be identified. This presentation examines a range of downstream processing examples and how the information has been used to design and 3D print new materials.

Learning Objectives:

1. Describe methodologies for X-ray CT imaging of bioprocess structures.

2. Discuss how chromatography structure relates to function.

3. Compare conventional DSP materials to 3D printed structures.