DATE: September 15, 2015
TIME: 8:00AM PT, 11:00AM ET
Skin Cell Motility: Integrins Lead the Way
You will learn about efforts to dissect mechanisms that underlie the directed migration of epidermal keratinocytes as they populate wounds or in cancer.
- The structure and function of matrix adhesion sites (focal contacts and hemidesmosomes) in skin cells (keratinocytes) in vivo and in vitro.
- The structural and signaling roles of complexes of hemidesmosome proteins in both adhesion and migration of keratinocytes.
- The interplay of focal contacts and hemidesmosome protein complexes in the generation of traction forces needed to move a keratinocyte forward.