WEBINAR: Advances in Live Cell Imaging

Skin Cell Motility: Integrins Lead the Way

You will learn about efforts to dissect mechanisms that underlie the directed migration of epidermal keratinocytes as they populate wounds or in cancer.

Learning outcomes:

• The structure and function of matrix adhesion sites (focal contacts and hemidesmosomes) in skin cells (keratinocytes) in  vivo and in vitro.


• The structural and signaling roles of complexes of hemidesmosome proteins in both adhesion and migration of keratinocytes.


• The interplay of focal contacts and hemidesmosome protein complexes in the generation of traction forces needed to move a keratinocyte forward.