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Cell Line Development
Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.
What's Popular in Cell Line Development
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MAY 30, 2023Drug Discovery & DevelopmentIntroduction Antibodies are the ideal therapeutic biomolecules due to their ability to bind to a variety of targets with ...MAY 18, 2023eBooksSingle-cell isolation is critical to numerous research areas, including rare-cell analysis, biologics discovery, and ste ...APR 24, 2023Cell & Molecular Biology
Published by Bindi M. Doshi, PhD on Mar 17, 2023 Organoids are 3D structures made up of cells that replic ...Sponsored By: MBL InternationalAPR 20, 2023Cancer
The bacteria Helicobacter pylori (H. pylori) can infect tissues in the mucosal layer that lines the stomach. ...Written By: Katie KokolusAPR 17, 2023Cancer
Endometrial cancer, characterized by the formation of malignant cells in the endometrium, the tissue that lines the insi ...Written By: Katie Kokolus
MAY 30, 2023
Drug Discovery & Development
Introduction Antibodies are the ideal therapeutic biomolecules due to their ability to bind to a variety of targets with
...
MAY 18, 2023
eBooks
Single-cell isolation is critical to numerous research areas, including rare-cell analysis, biologics discovery, and ste
...
APR 24, 2023
Cell & Molecular Biology
Published by Bindi M. Doshi, PhD on Mar 17, 2023 Organoids are 3D structures made up of cells that replic
...
Sponsored By:
MBL International
APR 20, 2023
Cancer
The bacteria Helicobacter pylori (H. pylori) can infect tissues in the mucosal layer that lines the stomach.
...
Written By:
Katie Kokolus
APR 17, 2023
Cancer
Endometrial cancer, characterized by the formation of malignant cells in the endometrium, the tissue that lines the insi
...
Written By:
Katie Kokolus
APR 16, 2023
Drug Discovery & Development
A new drug has successfully treated mouse and non-human primate models of a severe form of nonalcoholic fatty live
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Written By:
Annie Lennon
MAR 31, 2023
Cell & Molecular Biology
Labroots is happy to announce that registration is open for the 5th Annual Event in the Bioprocessing Virtual Event Seri
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Written By:
Laurence Tognetti, MSc
MAR 27, 2023
Genetics & Genomics
One of the most famous composers who ever lived, Ludwig van Beethoven, developed hearing loss. He apparently started to
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Written By:
Carmen Leitch
MAR 20, 2023
Cancer
Our body has mechanisms to regulate the immune system. Effective immunity requires the body to know when to ramp u
...
Written By:
Katie Kokolus
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APR 25, 2023 | 10:00 AMC.E. CREDITS
Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...MAR 30, 2023 | 5:00 PM
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...MAR 22, 2023 | 9:00 AMC.E. CREDITS
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
FEB 22, 2023 | 12:00 PM
Have you ever tried to access the genomic profiles of cell lines before using them in your preclinical experiments just to come up empty-handed? Maybe you’ve scoured public databases f...
Speaker:
Telmo Henriques, PhD
,
Jonathan Jacobs, PhD
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
Speaker:
Philipp Kukura
,
Francesco Reina
,
Matthew Kose-Dunn
,
Phil Allen
Sponsored By: Teledyne Photometrics
APR 25, 2023 | 10:00 AM
C.E. CREDITS
Date: April 25, 2023 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) A liquid biopsy is a non-invasive alternative to a surgical biopsy that enables researchers to learn a range of infor...
MAR 30, 2023 | 5:00 PM
Date: March 30, 2023 Time: 5:00pm (PST), 8:00pm (EST) March 31, 2023 9:00am (JST) Chimeric antigen receptor T cell (CAR-T) therapy is still challenging in targeting solid malignancies. The q...
MAR 22, 2023 | 9:00 AM
C.E. CREDITS
We have developed 3D-shaped hydrogel microparticle platforms to capture cells, as well as isolate and label their secretions. These “lab on a particle” systems enable sorting cel...
FEB 22, 2023 | 12:00 PM
Have you ever tried to access the genomic profiles of cell lines before using them in your preclinical experiments just to come up empty-handed? Maybe you’ve scoured public databases f...
Speaker:
Telmo Henriques, PhD
,
Jonathan Jacobs, PhD
FEB 15, 2023 | 7:00 AM
Date: February 15, 2023 Time: 7:00am (PST), 10:00pm (EST), 4:00pm (CET) While not all microscopy samples can fluoresce, all can scatter light, and this scattered light can be imaged. This ha...
Speaker:
Philipp Kukura
,
Francesco Reina
,
Matthew Kose-Dunn
,
Phil Allen
Sponsored By: Teledyne Photometrics
NOV 17, 2022 | 7:00 AM
C.E. CREDITS
Date: November 17, 2022 Time: 7:00am (PST), 10:00am (EST), 4:00pm (CET) In order to truly understand cell biology, researchers need easy-to-use tools that preserve the natural complexity of...
NOV 16, 2022 | 10:00 AM
Date: November 16, 2022 Time: 10:00am (PST), 1:00pm (EST), 7:00pm (CET) Eli Lilly, a global healthcare leader, has implemented a next generation research (NGR) initiative to improve the valu...
NOV 16, 2022 | 9:00 AM
Date: November 16, 2022 Time: 9:00am (PST), 12:00pm (EST), 6:00pm (CET) No more estimating. No more ranges. No more uncertainty. While PDX tumor models are crucial for gaining predictive ins...
NOV 08, 2022 | 8:00 AM
Date: November 08, 2022 Time: 8:00am (PST), 11:00am (EST), 5:00pm (CEST) While flow cytometry shines by its flexibility, it requires a high level of expertise in antibody panel development,...
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Tandem Mass Tags (TMT) have revolutionized the field of mass spectrometry by enabling simultaneous identification and quantification of protein expression from multiple samples in a single L...JUN 29, 2022 | 1:00 AM PDT
Lab Compliance Connect The world’s leading event for lab compliance solutions Lab Compliance Connect The world’s leading virtual event series for lab compliance solutions This 12...JUN 22, 2022 | 3:00 AM PDT
Please join us for Ion World 2022, a virtual conference that will provide an opportunity to hear from scientists around the world, on how they are advancing research in a broad range of appl...APR 27, 2023C.E. CREDITS
Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that explore basic and compl...JAN 25, 2022 | 1:00 AM PST
Europe - 10:00 AM Central European Time United Kingdom - 10:00 AM British Summer Time North America - 10:00 AM Central Standard Time Lab Compliance Connect – The world’s leading...
Tandem Mass Tags (TMT) have revolutionized the field of mass spectrometry by enabling simultaneous identification and quantification of protein expression from multiple samples in a single L...
JUN 29, 2022
| 1:00 AM PDT
Lab Compliance Connect The world’s leading event for lab compliance solutions Lab Compliance Connect The world’s leading virtual event series for lab compliance solutions This 12...
JUN 22, 2022
| 3:00 AM PDT
Please join us for Ion World 2022, a virtual conference that will provide an opportunity to hear from scientists around the world, on how they are advancing research in a broad range of appl...
APR 27, 2023
C.E. CREDITS
Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that explore basic and compl...
JAN 25, 2022
| 1:00 AM PST
Europe - 10:00 AM Central European Time United Kingdom - 10:00 AM British Summer Time North America - 10:00 AM Central Standard Time Lab Compliance Connect – The world’s leading...
JAN 10, 2022
| 7:30 AM PST
Bionano Genomics is transforming the way the world sees the genome. The 2022 Symposium will feature usage of optical genome mapping in research, clinical research and clinical validation......
It’s an Open House! Come join us virtually where you will have the opportunity to network with colleagues and learn about the latest developments in life science research. The Leica Bi...
OCT 04, 2021
| 8:00 AM PDT
To SBI2 members and sponsors, On behalf of the Society of Biomolecular Imaging and Informatics Board of Directors, I am pleased to announce the 8th annual High Content conference which will...
SEP 14, 2021
| 7:00 AM PDT
Working in Tandem : 1st annual TMT Symposia Tandem Mass Tags (TMT) are isobaric labels that allow for simultaneous identification and quantification of protein expression from multiple sampl...