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      • Medical Laboratory Performance Benchmarking - Current Practice and Future Perspectives
        MAY 19, 2022
        Medical Laboratory Performance Benchmarking - Current Practice and Future Perspectives
      • Automated sample preparation for reproducible clinical proteomics
        MAY 19, 2022
        Automated sample preparation for reproducible clinical proteomics
      • Guardians of Your Science, Ask the Expert Series
        MAY 24, 2022
        Guardians of Your Science, Ask the Expert Series
      • A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
        MAY 24, 2022
        A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      • Next-Generation Sequencing (NGS) Assessment of Homologous Recombination Deficiency (HRD): Expanding NGS Data to View Events Associated with Genomic Instability
        MAY 24, 2022
        Next-Generation Sequencing (NGS) Assessment of Homologous Recombination Deficiency (HRD): Expanding NGS Data to View Events Associated with Genomic Instability
      • A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
        MAY 25, 2022
        A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
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      • On the way towards personalized medicine: Gene therapy AAV characterization by capillary electrophoresis (CE) and liquid chromatography mass spectrometry (LC-MS)
        MAY 17, 2022
        On the way towards personalized medicine: Gene therapy AAV characterization by capillary electrophoresis (CE) and liquid chromatography mass spectrometry (LC-MS)
      • Novel tools for cell line engineering with CRISPR-Cas9
        MAY 17, 2022
        Novel tools for cell line engineering with CRISPR-Cas9
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        MAY 17, 2022
        Technology Platforms for Monoclonal Antibody Development and Production
      • Implementing shallow screening strategies to accelerate microbial strain improvement
        MAY 12, 2022
        Implementing shallow screening strategies to accelerate microbial strain improvement
      • T cell culture - Fine-tuning your T cell research workflow step by step
        MAY 12, 2022
        T cell culture - Fine-tuning your T cell research workflow step by step
      • Conserving California: Applying Whole Genome Sequencing in the California Conservation Genomics Project (CCGP)
        MAY 11, 2022
        Conserving California: Applying Whole Genome Sequencing in the California Conservation Genomics Project (CCGP)
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          CDC Investigation into Severe Hepatitis Cases in over 100 Children: What to Know
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          The Pioneering Project to Change How We Predict Space Weather
        • The Labroots 2022 Genetics & Genomics Virtual Event Poster Winner: Leveraging STR detection via STRling to identify possible pathogenic variants
          The Labroots 2022 Genetics & Genomics Virtual Event Poster Winner: Leveraging STR detection via STRling to identify possible pathogenic variants
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          Single-Cell Atlas Reveals Gene Activity Across Human Tissues
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          New Study Identifies Heart Attack Risk Factors for Younger People
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        • A Single Mutation Made Us More Susceptible to Cancer
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    Cell Line Development

    Cell Line Development: Stable cell lines are widely used in a number of important applications including biologics (e.g. recombinant protein and monoclonal antibody) production, drug screening, and gene functional studies. The process of developing stable cell lines often starts with transfecting selected host cells, typically CHO or HEK 293 cells, with desired plasmids. After transfection, researchers then screen and quantify high-expressing clones. Once these high producers are identified, the cell lines and/or the proteins produced by the cells are validated. The manual screening methods traditionally used for cell line development are time-consuming and labor-intensive, creating a great demand for high-throughput, automated solutions for such efforts.

    What's Popular in Cell Line Development

    Trending News

    • APR 28, 2022
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      Keto Molecule Shows Promise for Treating Colorectal Cancer
      APR 28, 2022
      Keto Molecule Shows Promise for Treating Colorectal Cancer
      A molecule produced when on low-carbohydrate ketogenic diets suppresses the growth of colorectal tumors in the lab. The ...
      Written By: Annie Lennon
      APR 25, 2022
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      Exercise Reduces Proliferation of Colon Cancer Cells
      APR 25, 2022
      Exercise Reduces Proliferation of Colon Cancer Cells
      Substantial evidence supports the association between exercise and reduced risk of colon cancer.  Physical act ...
      Written By: Katie Kokolus
      APR 21, 2022
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      An Immune Cell Subset Provides New Insights Into IBD
      APR 21, 2022
      An Immune Cell Subset Provides New Insights Into IBD
      Innate lymphoid cells (ILCs) are part of the innate immune system, a generalized response to pathogens. These cells are ...
      Written By: Carmen Leitch
      APR 20, 2022
      Immunology
      Rare Soil Microbe Shows Promise as New Antibiotic
      APR 20, 2022
      Rare Soil Microbe Shows Promise as New Antibiotic
        Antibiotic resistance has increased the demand for new antibiotic treatments. Now, researchers have found that a ...
      Written By: Annie Lennon
      APR 15, 2022
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      Immune Cell Fingerprints Can Help Reveal New Autoimmune Disease Treatments
      APR 15, 2022
      Immune Cell Fingerprints Can Help Reveal New Autoimmune Disease Treatments
      The immune system is an incredibly complex system that has to be able to rapidly spring into action, and then shut down ...
      Written By: Carmen Leitch
    APR 28, 2022
    Drug Discovery & Development
    Keto Molecule Shows Promise for Treating Colorectal Cancer
    APR 28, 2022
    Keto Molecule Shows Promise for Treating Colorectal Cancer
    A molecule produced when on low-carbohydrate ketogenic diets suppresses the growth of colorectal tumors in the lab. The ...
    Written By: Annie Lennon
    APR 25, 2022
    Cancer
    Exercise Reduces Proliferation of Colon Cancer Cells
    APR 25, 2022
    Exercise Reduces Proliferation of Colon Cancer Cells
    Substantial evidence supports the association between exercise and reduced risk of colon cancer.  Physical act ...
    Written By: Katie Kokolus
    APR 21, 2022
    Immunology
    An Immune Cell Subset Provides New Insights Into IBD
    APR 21, 2022
    An Immune Cell Subset Provides New Insights Into IBD
    Innate lymphoid cells (ILCs) are part of the innate immune system, a generalized response to pathogens. These cells are ...
    Written By: Carmen Leitch
     
     
    APR 20, 2022
    Immunology
    Rare Soil Microbe Shows Promise as New Antibiotic
    APR 20, 2022
    Rare Soil Microbe Shows Promise as New Antibiotic
      Antibiotic resistance has increased the demand for new antibiotic treatments. Now, researchers have found that a ...
    Written By: Annie Lennon
    APR 15, 2022
    Immunology
    Immune Cell Fingerprints Can Help Reveal New Autoimmune Disease Treatments
    APR 15, 2022
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    The immune system is an incredibly complex system that has to be able to rapidly spring into action, and then shut down ...
    Written By: Carmen Leitch
    APR 14, 2022
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    COVID-19 Drug Combo More Effective than Single Drugs
    APR 14, 2022
    COVID-19 Drug Combo More Effective than Single Drugs
    COVID-19 is more effectively treated by a combination of drugs than singular drugs alone. The corresponding study was pu ...
    Written By: Annie Lennon
    APR 08, 2022
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    APR 08, 2022
    How Zinc Can Boost the Function of the Immune System
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    Written By: Carmen Leitch
    MAR 11, 2022
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    Understanding the 'Security Guards' of Our Tissues - γδ T Cells
    MAR 11, 2022
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    MAR 07, 2022
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    Webinars

    • MAY 24, 2022 9:00 AM PDT
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      MAY 24, 2022 9:00 AM PDT
      A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
      Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
      Speaker: Andrew Mancini, Ph.D
      Sponsored By: MaxCyte
      MAY 25, 2022 10:00 AM PDT
      A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
      MAY 25, 2022 10:00 AM PDT
      A digital PCR-based protocol to detect and quantify RNA editing...
      Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
      Speaker: Rémi Buisson
      Sponsored By: Thermo Fisher Scientific
      MAY 26, 2022 9:00 AM PDT
      Lightning CE-SDS and fast cIEF workflows for protein therapeutics characterization with demonstrated high-throughput
      MAY 26, 2022 9:00 AM PDT
      Lightning CE-SDS and fast cIEF workflows for protein therapeutics...
      Date: May 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) In early drug development, lead clone selection requires large number of clones screening in cell line development. Develo...
      Speaker: Zhichang Yang
      Sponsored By: SCIEX
      JUN 28, 2022 9:00 PM PDT
      Mastering basic techniques for cancer cell culture
      JUN 28, 2022 9:00 PM PDT
      Mastering basic techniques for cancer cell culture
      Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
      Speaker: Brittany Balhouse
      Sponsored By: Thermo Fisher Scientific/Gibco
      MAY 03, 2022 8:00 AM PDT
      Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
      MAY 03, 2022 8:00 AM PDT
      Unlocking the genomics of cancer using Sanger sequencing and fragment...
      Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
      Speaker: Steve Jackson, PhD
      Sponsored By: Thermo Fisher Scientific
    MAY 24, 2022 9:00 AM PDT
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    MAY 24, 2022 9:00 AM PDT
    A cGMP Compatible, Non-Viral CAR T Cell Manufacturing Process
    Date: May 24, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) Recent breakthroughs in autologous cellular therapies have generated tremendous excitement for the industry; however, thes...
    Speaker: Andrew Mancini, Ph.D
    Sponsored By: MaxCyte
    MAY 25, 2022 10:00 AM PDT
    A digital PCR-based protocol to detect and quantify RNA editing events at hotspots
    MAY 25, 2022 10:00 AM PDT
    A digital PCR-based protocol to detect and quantify RNA editing...
    Date: May 25, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Programmable RNA base editors are excellent tools to modify RNA transcripts at precise locations or designated hotspots. P...
    Speaker: Rémi Buisson
    Sponsored By: Thermo Fisher Scientific
     
     
    MAY 26, 2022 9:00 AM PDT
    Lightning CE-SDS and fast cIEF workflows for protein therapeutics characterization with demonstrated high-throughput
    MAY 26, 2022 9:00 AM PDT
    Lightning CE-SDS and fast cIEF workflows for protein therapeutics...
    Date: May 26, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 6:00pm (CEST) In early drug development, lead clone selection requires large number of clones screening in cell line development. Develo...
    Speaker: Zhichang Yang
    Sponsored By: SCIEX
    JUN 28, 2022 9:00 PM PDT
    Mastering basic techniques for cancer cell culture
    JUN 28, 2022 9:00 PM PDT
    Mastering basic techniques for cancer cell culture
    Date: June 29, 2022 Time: 12:00pm (PST), 2:00pm (EST), 8:00pm (CEST) The burden of antimicrobial resistance (AMR) has been acknowledged worldwide by leading health institutes. Besides the ne...
    Speaker: Brittany Balhouse
    Sponsored By: Thermo Fisher Scientific/Gibco
    MAY 03, 2022 8:00 AM PDT
    Unlocking the genomics of cancer using Sanger sequencing and fragment analysis
    MAY 03, 2022 8:00 AM PDT
    Unlocking the genomics of cancer using Sanger sequencing and fragment...
    Cancer is a disease of the genome, and as such, tools that can analyze the genome are instrumental in understanding the mechanisms that lead to cancer, detecting cancerous cells, and providi...
    Speaker: Steve Jackson, PhD
    Sponsored By: Thermo Fisher Scientific
    APR 28, 2022 8:00 AM PDT
    Achieving clinical quality for human iPSC generation and expansion
    APR 28, 2022 8:00 AM PDT
    Achieving clinical quality for human iPSC generation and expansion
    Date: April 28, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Human pluripotent stem cells (PSCs) and their derivatives hold great potentials in...
    Speaker: Dr. Boris Greber , Dr. Chao Sheng
    Sponsored By: Miltenyi Biotec
    APR 26, 2022 7:00 AM PDT
    C.E. CREDITS
    Modelling of cellular interactions in mixed murine organoids
    APR 26, 2022 7:00 AM PDT
    Modelling of cellular interactions in mixed murine organoids
    Date: April 26, 2022 Time: 7:00am (PDT), 10:00am (EDT), 4:00pm (CET) Cell competition is a mechanism of interaction that dictates cell selection based on differences in cellular fitness. We...
    Speaker: Saskia J.E Suijkerbuijk
    Sponsored By: Andor
    C.E. CREDITS
    Optimising Cell Line Development for Bioprocessing
    Optimising Cell Line Development for Bioprocessing
    In the last decades, the upstream processing in biopharma industry has been revolutionized regarding the production of bioactive materials such as monoclonal antibodies, proteins and biother...
    Speaker: Sami Ullah, PhD
    Presented at: Bioprocessing 2022
    C.E. CREDITS
    Introduction to Next Generation Bioanalytics Development
    Introduction to Next Generation Bioanalytics Development
    Viral Vector gene therapy has been the focus of intense research driven by the safety profile and several clinical breakthroughs. As of March 2022, there are two viral vector gene therapies...
    Speaker: Nagarjun Kasaraneni, PhD
    Presented at: Bioprocessing 2022
    See More
    Cell Line Development
    Webinars
    See All

    Virtual Events

    • JUN 22, 2022 3:00 AM PDT
      Ion World 2022: The virtual event that gets real about NGS
      JUN 22, 2022 3:00 AM PDT
      Ion World 2022: The virtual event that gets real about NGS
      Please join us for Ion World 2022, a virtual conference that will provide an opportunity to hear from scientists around the world, on how they are advancing research in a broad range of appl...
      JUN 29, 2022 1:00 AM PDT
      Lab Compliance Connect
      JUN 29, 2022 1:00 AM PDT
      Lab Compliance Connect
      Lab Compliance Connect The world’s leading event for lab compliance solutions Lab Compliance Connect The world’s leading virtual event series for lab compliance solutions This 12...
      APR 28, 2022
      C.E. CREDITS
      Stago EdVantage Virtual University
      APR 28, 2022
      Stago EdVantage Virtual University
       Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that explore basic and compl...
      JAN 25, 2022 1:00 AM PST
      Lab Compliance Connect
      JAN 25, 2022 1:00 AM PST
      Lab Compliance Connect
      Europe - 10:00 AM Central European Time United Kingdom - 10:00 AM British Summer Time North America - 10:00 AM Central Standard Time Lab Compliance Connect – The world’s leading...
      JAN 10, 2022 7:30 AM PST
      Bionano Genomics 2022 Symposium
      JAN 10, 2022 7:30 AM PST
      Bionano Genomics 2022 Symposium
      Bionano Genomics is transforming the way the world sees the genome. The 2022 Symposium will feature usage of optical genome mapping in research, clinical research and clinical validation......
    JUN 22, 2022 3:00 AM PDT
    Ion World 2022: The virtual event that gets real about NGS
    JUN 22, 2022 3:00 AM PDT
    Ion World 2022: The virtual event that gets real about NGS
    Please join us for Ion World 2022, a virtual conference that will provide an opportunity to hear from scientists around the world, on how they are advancing research in a broad range of appl...
     
     
    JUN 29, 2022 1:00 AM PDT
    Lab Compliance Connect
    JUN 29, 2022 1:00 AM PDT
    Lab Compliance Connect
    Lab Compliance Connect The world’s leading event for lab compliance solutions Lab Compliance Connect The world’s leading virtual event series for lab compliance solutions This 12...
    APR 28, 2022
    C.E. CREDITS
    Stago EdVantage Virtual University
    APR 28, 2022
    Stago EdVantage Virtual University
     Stago EdVantage Virtual University is an educational platform that demystifies hemostasis testing with on-demand webinars and a virtual exhibit hall that explore basic and compl...
    JAN 25, 2022 1:00 AM PST
    Lab Compliance Connect
    JAN 25, 2022 1:00 AM PST
    Lab Compliance Connect
    Europe - 10:00 AM Central European Time United Kingdom - 10:00 AM British Summer Time North America - 10:00 AM Central Standard Time Lab Compliance Connect – The world’s leading...
    JAN 10, 2022 7:30 AM PST
    Bionano Genomics 2022 Symposium
    JAN 10, 2022 7:30 AM PST
    Bionano Genomics 2022 Symposium
    Bionano Genomics is transforming the way the world sees the genome. The 2022 Symposium will feature usage of optical genome mapping in research, clinical research and clinical validation......
    Navigating Spatial Biology - Take that next step with Leica Biosystems
    Navigating Spatial Biology - Take that next step with Leica Biosystems
    It’s an Open House! Come join us virtually where you will have the opportunity to network with colleagues and learn about the latest developments in life science research. The Leica Bi...
    OCT 04, 2021 11:00 AM EDT
    8th Annual Conference: SBI2 High Content
    OCT 04, 2021 11:00 AM EDT
    8th Annual Conference: SBI2 High Content
    To SBI2 members and sponsors, On behalf of the Society of Biomolecular Imaging and Informatics Board of Directors, I am pleased to announce the 8th annual High Content conference which will...
    SEP 14, 2021 7:00 AM PDT
    Working in Tandem - 1st Annual TMT Symposium
    SEP 14, 2021 7:00 AM PDT
    Working in Tandem - 1st Annual TMT Symposium
    Working in Tandem : 1st annual TMT Symposia Tandem Mass Tags (TMT) are isobaric labels that allow for simultaneous identification and quantification of protein expression from multiple sampl...
    SEP 08, 2021 6:00 AM PDT
    xMAP® Connect Virtual Conference (On-Demand)
    SEP 08, 2021 6:00 AM PDT
    xMAP® Connect Virtual Conference (On-Demand)
    Luminex's xMAP® Technology enables the evaluation of up to 500 analytes simultaneously in a single well, known as multiplexing. xMAP Technology uses color-coded microspheres as the substrate...
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