How Artificial Intelligence can facilitate the use of cardiac biomarkers?

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • MD, PGDHM, PGDBA, Professor, Department of Biochemistry, G.B.Pant Institute of Postgraduate Medical Education & Research (GIPMER), Associated to Maulana Azad Medical College
    Biography

      Prof. (Dr) Pradeep Kumar Dabla is an experienced Chairperson with a demonstrated history of more than 17 yrs of Leadership & Administration while working in the hospital & health care industry. He is a laboratory physician skilled in Medical Devices, Molecular Biology, Biotechnology, Laboratory Medicine and Clinical Research. He is a strong research professional with a NABL Assessor ISO 15189:2012 focused in Medical Laboratory from National Accreditation Board for Testing and Calibration Laboratories (NABL), Quality Council, Govt. of India. He has assessed more than 100 medical labs for NABL accreditation till date. He has been closely associated with National Accreditation Board for Hospitals & Healthcare Providers (NABH) for preparing & maintaining quality services for Chacha Nehru Bal Chikitsalya (CNBC), first public sector superspeciality hospital to receive accreditation while working as Head, Deptt of Biochemistry & all labs. Currently, he is working as a Professor, Department of Biochemistry, G.B.Pant Institute of Postgraduate Medical Education & Research (GIPMER), Associated Maulana Azad Medical College (MAMC), Govt of NCT of Delhi. He is also serving as Consultant, International Core Committee of IFCC Task Force for Young Scientists (IFCC-TFYS), Core Member APFCB-Communication & Publication Committee and Member IFCC C-MHBLM (Emerging Technologies Division). He demonstrated leadership skills with team ability and served IFCC as Chair IFCC-TFYS (2015-2019) while working for networking, training, education and support programmes for young colleagues. He has completed MBBS from Maulana Azad Medical College, Delhi University and MD (Biochemistry) from Lady Hardinge Medical College, Delhi University, India. Further, to increase the proficiency in management, he pursued Post-graduation in the Business Administration & Hospital Management. He is also qualified with Advanced Training in Supply Chain Management, Govt. of NCT Delhi, India. Due to keen interest in research and laboratory medicine, he has been awarded Thrice for his research work in “Postmenopausal Women CAD Risk & Gene Polymorphism” and “Diabetic CAD Risk” and received other Five Awards & Travel Grants at International level and been invited many times as speaker, chair at National & International congresses. He has more than 40 research papers to his credit in reputed National & International journals apart from 4 book chapters, 2 books and more than 30 abstracts as a part of invited talks and papers presented. He is associated with reputed journals as editor, reviewer and advisory board member.


    Abstract

    Biomarkers play a vital role in disease detection and treatment follow-up. It is important to note that the diseases in the early stage are typically treated with the greatest probability of success. Therefore, the early detection of biomarkers is very important in the case of cancer, cardiovascular disorders, and other pathological conditions. Biomarkers may includes antigens, DNA, mRNA, and enzymes. Cardiac biomarkers are part of the standards of care and guidelines for myocardial infarction and heart failure. Cardiac biomarkers represent also an evolving field of innovations to improve the prevention, diagnosis and monitoring of cardiovascular disorders. The ultimate goal behind the use of biomarkers for diagnosis is to develop reliable and cost-effective powerful detection tools for early diagnosis of diseases and disorders. A serial combination testing of a sensitive early marker (e.g., H-FABP, myoglobin, or CK-MB isoforms) and one of the cardiac-specific troponins (cTnT or cTnI) offers the best approach. Identifying the needs of physicians and potential new candidates for routine requires both multidisciplinary exchanges and translational research. Data mining and machine learning offer now more possibilities for this quest. Laboratorians play a key role after that to implement new biomarkers in routine practices and check the performances according to practices and accreditation specifications. Education and its continuing cycle is glue for an efficient integration in clinical practices and appropriate use by health care professionals. Thus, biomarker detection platforms must therefore be adapted for a rapid and sensitive point-of-care testing.

    Learning ObjectivesL

    1. Describe the value of cardiac biomarkers in emergency settings

    2. Artificial Intelligence (AI) and its applications in cardiovascular early risk prediction

    3. Present the needs for training and continuing education of health care professionals


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