JAN 30, 2020 9:00 AM PST

An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening

Speaker

Abstract
DATE:  January 30, 2020
TIME:   9:00am PST, 12:00pm EST
 
Recent advances in in vitro 3D cellular culture technologies, such as organoids, rapidly developed and established novel, more physiologically relevant models for basic biology and clinical applications. Traditionally, high-throughput microfluidics and other similar technologies have relied on two-dimensional (2D) cell models for the study of various human conditions and diseases, yet they are not compatible with 3D culture. I will discuss the development of an automatic and dynamic microfluidic ex vivo organoid culture modeling system to facilitate and accelerate preclinical research and the development of personalized treatment strategies. This integrated platform combines microfluidics, automatic dynamic and temporal stimulations (ie combinatorial drug screenings), combined with in silico data analysis and prediction tools. The platform can be used to advance the capabilities of research on cancer organoids models, screen and mirror real life patient chemotherapy treatments and ultimately facilitate treatment decisions for the development of personalized therapies.
 
Learning Objectives:
  • Understand the difference between traditional and microfluidic based cell culture technologies
  • Learn about applying biomedical engineering techniques to advance current 3D cell culture technologies, specifically cancer organoid culture systems 
  • Discover the potential application and capabilities of automatic, high throughput, and dynamic cell culture platforms  
 
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JAN 30, 2020 9:00 AM PST

An Automated Cancer Organoid Culture Platform to Accelerate Research and Drug Screening


Specialty

Cancer Research

Cell Biology

Molecular Biology

Cell Culture

Immunology

Cancer Therapeutics

Biotechnology

Biomarkers

Cancer Diagnostics

Molecular Diagnostics

Genetics

Oncology

Drug Discovery

Clinical Research

Biochemistry

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