NOV 14, 2018 12:00 PM PST

Automated Variant Classification in QIAGEN Clinical Insight Shows Near Perfect Concordance with ClinVar Expert Panel Assessments

Sponsored by: QIAGEN
Speaker

Abstract

As the compendium of putatively disease causing variants expands, gathering the most current and accurate information is critical to computing variant classifications. The QIAGEN knowledgebase includes the most extensively curated database of variant specific publications, including functional studies and clinical cases. QIAGEN Clinical Insight (QCI) leverages this information to invoke all ACMG rules to automatically compute variant classifications. In this webinar, you will see how QCI classifies over 6,000 ClinVar expert panel assessed BRCA1 and BRCA2 variants with incredible accuracy. With respect to clinical actionability, QCI automated ACMG classification was 99.6% concordant with ENIGMA expert panel variant assessments. This level of accuracy speaks to the quality of the clinical, functional, and population level data in the knowledgebase, as well as the robustness of the underlying algorithm used to apply the ACMG guidelines.


Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 14, 2021 7:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
APR 01, 2021 8:00 AM PDT
C.E. CREDITS
APR 01, 2021 8:00 AM PDT
Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
JUL 15, 2021 8:00 AM PDT
C.E. CREDITS
JUL 15, 2021 8:00 AM PDT
Date: July 15, 2021 Time: 8:00am (PDT), 11:00am (EDT) High dimensional full spectrum flow cytometry grants unprecedented access to previously unattainable parameters in cellular biology. Flu...
MAR 16, 2021 10:00 AM PDT
C.E. CREDITS
MAR 16, 2021 10:00 AM PDT
Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
NOV 14, 2018 12:00 PM PST

Automated Variant Classification in QIAGEN Clinical Insight Shows Near Perfect Concordance with ClinVar Expert Panel Assessments

Sponsored by: QIAGEN

Specialty

Cancer Research

Dna Sequencing

Personalized Medicine

Clinical Diagnostics

Immunity

Biotechnology

Immunotherapy

Antibodies

Flow Cytometry

Research

Immuno-Oncology

Cancer Therapeutics

Gene Expression

Dna

Big Data

Geography

North America33%

Asia33%

Europe33%

Registration Source

Website Visitors100%

Job Title

Student33%

Facility/Department Manager33%

Medical Laboratory Technician33%

Organization

Life Science Company33%

Manufacturer - Other33%

Academic Institution33%


Show Resources
Loading Comments...
Show Resources