FEB 08, 2017 12:00 PM PST

Availability and Management of Genetically Engineered Swine Models for Biomedical Research

C.E. CREDITS: RACE
Speakers
  • Research Assistant Professor, Project Director, National Swine Research and Resource Center
    Biography
      Dr. Eric Walters is a world-renowned scientist in the area of genetic engineering and swine biomedical models. His group has made and is currently working on swine models for various human diseases such as cancer, retinitis pigmentosa, xenotransplantation, and congenital heart defects. Dr. Walters has been able to travel around the world giving seminars and attending various scientific meetings. He has written 45 abstracts, 35 peer reviewed manuscripts, and 6 book chapters. In addition to the transgenic research, he also investigates the transcriptional regulation of cryopreserved porcine embryos.

      Dr. Walters is a 1991 graduate of Spoon River Valley High School. Following his graduation from Western Illinois University in 1995 with a Bachelors degree in Agricultural Science, he completed his Masters degree at the University of Illinois and then received his PhD in Reproductive Biology at the U of I in 2000. Dr. Walters was a post-doctoral researcher for the Beckman Institute at the University of Illinois and a senior scientist for a small biotechnology company. In 2003, he moved to Columbia, Missouri for a post-doctoral position in the College of Veterinary Medicine at the University of Missouri. Currently, he is a Research Assistant Professor in the Division of Animal Sciences and Project Director for the National Swine Resource and Research Center at the University of Missouri.

    Abstract:

    DATE: February 8, 2017
    TIME: 12:00pm PT, 3:00pm ET

    Large animal models have recently become a staple in biomedical research.  The pig’s similarities to humans in terms of genetics, anatomy, and physiology have allowed the pig to gain momentum as a biomedical model.  On a nucleotide basis, the pig genome is 3 times closer to the human than rodents are to humans.  Although there are some anatomical differences between the human and pig, the pig is still becoming the model of choice for many human diseases.  In 2003, the National Institutes of Health developed the infrastructure for a central resource center for swine models for human health and diseases.  The National Swine Resource and Research Center (NSRRC) was developed to provide valuable swine models to investigators across the country.  Currently, the NSRRC has 60 models available to the scientific community with an additional 15 models in various stages of production and characterization.   Management of genetically modified swine models can range from standard housing to highly specialized housing which may be necessary for the disease model.   Maintenance or breeding of genetically modified swine models also ranges from strains being maintained in the heterozygous/monoallelic state while others can be maintained in the homozygous/biallelic state.  Although there may be specialized needs for some models, in general genetically modified swine models can be maintained as any other research pigs.  Biomedical research for human health and disease has begun to incorporate the swine model as the large animal of choice.  

    Learning Objectives:

    • To determine the availability of swine models for investigators to request
    • To determine specific management skills for genetically modified swine models

    Show Resources
    You May Also Like
    SEP 05, 2019 04:00 PM CEST
    C.E. CREDITS
    SEP 05, 2019 04:00 PM CEST
    DATE: September 5, 2019TIME: 7:00am PT, 10:00am ET, 4:00pm CEST PCR (Polymerase Chain Reaction) has gone through a massive evolution since its development in 1983. Besides it...
    JUN 05, 2019 05:00 PM CEST
    C.E. CREDITS
    JUN 05, 2019 05:00 PM CEST
    DATE: June 5, 2019TIME: 8:00am PDT, 11:00am EDT, 5:00pm CEST Eukaryotic cell cultures respond to the most subtle influence. Apart from the risk of contamination, minimal chan...
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    NOV 18, 2019 07:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    NOV 18, 2019 07:00 AM PST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: November 18, 2019TIME: 7:00am PST, 11:00am EST, 4:00pm CEWT How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop th...
    MAY 16, 2019 04:00 PM CEST
    C.E. CREDITS
    MAY 16, 2019 04:00 PM CEST
    DATE: May 16, 2019TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST The emergence of NGS is revolutionizing the microbiological sciences and transforming medicine. Deep sequencing has...
    AUG 27, 2019 09:00 AM PDT
    C.E. CREDITS
    AUG 27, 2019 09:00 AM PDT
    DATE: August 27, 2019 TIME: 9:00am PDT, 12:00pm EDT Immunotherapies targeting PD-1 or PD-L1 have proven remarkably effective for treating cancer in some patients, with considerabl...
    Loading Comments...
    Show Resources