FEB 27, 2019 3:00 PM PST

BASKET Trials: Biomarker Driven Drug Development

Presented at: Drug Discovery 2019
Speaker
  • Professor of Medicine (Oncology) and of Radiology (Molecular Imaging Program at Stanford), Director Phase I Clinical Research, Director, Translational Oncology Program, Stanford University
    BIOGRAPHY

Abstract

Dramatic responses observed with targeted agents in the ‘right’ genomic context have fueled large scale sequencing efforts to identify ‘effective’ treatments for a given patient. In order to expeditiously evaluate a targeted agent against a potential ‘driver’ genetic aberration, so-called Basket trials are conducted. Basket trials enroll patients with multiple tumor types that carry a common genetic aberration and evaluate a single targeted treatment regimen. I will discuss the rationale, design, and challenges in conducting Basket trials.

Learning Objectives:

1. Learn about when to consider conducting a Basket trial and how to design it
2. Learn about the promises and challenges of identifying patients based on genomic aberrations
 


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FEB 27, 2019 3:00 PM PST

BASKET Trials: Biomarker Driven Drug Development

Presented at: Drug Discovery 2019

Specialty

Cancer

Clinical Diagnostics

Immunity

Cell Culture

Immunotherapy

Biotechnology

Antibodies

Virology

Research

Immunology

Diagnostics

Life Sciences

Dna Sequencing

Big Data

Cell

Geography

North America40%

Europe40%

Asia20%

Registration Source

Website Visitors100%

Job Title

Student50%

Medical Doctor/Specialist25%

Medical Laboratory Technician25%

Organization

Academic Institution60%

Manufacturer - Other20%

Clinical Laboratory20%


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