The immune system is complex and dynamic, focused on defending the body from a host of pathogens ranging from viruses to cancer. A number of different mechanisms have evolved that help the body fight to control cancers and other disease. Unfortunately, sometimes these defenses break down and become compromised, enabling cancers to survive and grow within the host.
Recent breakthroughs have shown that Immunotherapeutic approaches may be successful in helping the host's immune system battle cancer, providing the body with ways to protect itself from cancer. Key to making this work is an understanding of both who will benefit from the therapy and at what stage in disease progression the therapy will be effective. In our discussion we will look at how biomarker development can aide in addressing these challenges. We will cover:
• Overview of Immunotherapies & their mechanisms of action
• Biomarkers associated with Immunotherapies
• Biomarker clinical testing
• Immunotherapy adverse reactions & success stories