Amy Mathers, MD, D(ABMM) is a tenured Associate Professor of Medicine and Pathology at the University of Virginia. She acts as Clinical Director of the Adult Antimicrobial Stewardship Program and Associate Director of Clinical Microbiology for the University of Virginia Medical Center. She has focused much of her research on the urgent clinical problem of antimicrobial resistance in Enterobacteriaceae. Molecular characterization has included analysis of mobile resistance mechanisms with evaluation of plasmid evolution and mobility across species with next generation sequencing paired with more traditional techniques. With support from the Centers for Disease Control and Prevention she has investigated the role that the hospital plumbing environment can play in evolution and dissemination of carbapenemase genes.