DEC 09, 2020 7:00 AM PST

Characterization of RNA therapeutics from small to large

Sponsored by: SCIEX
C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Biopharma EMEAI Marketing and Market Development Manager, SCIEX. Scientific Advisor, Horváth Csaba Memorial Laboratory, University of Pannonia.
    Biography
      Dr. Stephen Lock obtained his PhD in Physical Organic Chemistry from the University College of Swansea in 1993 and is a chartered chemist and a member of the Royal Society of Chemistry. Previously a lecturer of Chemistry at the University of Hull and a senior scientist at CCFRA he has worked for SCIEX™ in various technical roles for over 20 years. He has over 25 years' experience in Analytical Chemistry and has presented at over 80 international meetings around the world.
      Steve is currently the EMEA BioPharma Marketing and Market Development Manager of SCIEX and is also an Adjunct Professor at the University of Pannonia where he acts in a volunteer role as the Scientific Advisor for the Horváth Csaba Memorial Laboratory lead by Prof. Andras Guttman. At the Horváth Csaba Memorial Laboratory Steve provides technical advice and supports the groups fundamental research and development of new applications in the area of CE and CE-MS.


    Abstract
    Date:  December 9, 2020
    Time: 7:00am (PST),  10:00am (EST)
     
    In this talk we will discuss the new analytical approaches to characterize RNA molecules from small oligonucleotides to larger messenger RNA.
    The interest in RNA therapeutics is growing whether it is using antisense oligonucleotides (ASOs), aptamers, siRNAs and more recently synthetic mRNAs to control disease-relevant genes. Such drugs can engage targets that were otherwise difficult to reach by small molecules and proteins and therefore opens new avenues to treat disease.
    The solutions demonstrated in this webinar use commercially available kits and techniques such as capillary electrophoresis (CE) and Liquid chromatography (LCMS) to characterize RNA targets. During the presentation, you will understand where each technique fits into the analytical scientist’s toolbox.
     
    Learning Objectives
    • Summarize how CE provides highly resolved separation and detection of RNA molecules
    • Discover how the LCMS provides in-depth characterization of antisense oligonucleotides
    • Explain how CE is being used to speed up RNA aptamer research
    • Recognize how CE methods can be modified to separate small and large RNA molecules.
     
     
    Webinars will be available for unlimited on-demand viewing after live event.
     
    LabRoots is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E. ® Program. By attending this webinar, you can earn 1 Continuing Education credit once you have viewed the webinar in its entirety.

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