Clinical Interpretation of Sequence Variants

The advent of massively parallel sequencing by next generation sequencing platforms now allow genomic approaches for individualizing healthcare. Genomic sequencing data reveals variants in genes related to drug metabolism that may affect efficacy or response. This presentation will describe the potential of NGS data for companion diagnostics or therapeutics and its implementation into clinical laboratories. Evaluating pharmacogenetic targets through exome analysis as well as through targeted gene panels will be discussed.