NOV 11, 2015 6:00 AM PST

Clinical next-generation sequencing for precision cancer therapeutics

Speaker

Abstract

Next-generation sequencing has emerged as a valuable tool for generating patient-specific genetic information for clinical diagnostics and optimal selection of targeted therapies. The heterogeneous somatic mutational landscape in cancer makes NGS technologies particularly appealing due to their ability to accurately and simultaneously detect multiple mutations across many genes.  Accordingly, oncologists are increasingly recognizing the importance of mutation assessment prior to initiating therapy with targeted therapeutic agents.  Issues that must be considered with NGS include technological limitations and opportunities, bioinformatics, test validation requirements, and reporting complexities. Participants will better understand and assess current clinical NGS testing modalities, including the necessary steps required for selecting a NGS assay.  The presentation will specifically emphasize the utility of NGS testing in precision oncology with illustrative case examples.

Learning objectives:

1. Discuss the basic concepts of next-generation sequencing
2. Define the complexities of detecting somatic mutations using tumor-derived DNA
3. Describe the advantages and limitations of clinical NGS for precision oncology
 


Show Resources
You May Also Like
MAY 11, 2021 10:00 AM PDT
C.E. CREDITS
MAY 11, 2021 10:00 AM PDT
Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
SEP 14, 2021 7:00 AM PDT
C.E. CREDITS
SEP 14, 2021 7:00 AM PDT
Date: September 14, 2021 Time: 7am PDT, 10am EDT, 4pm CEST A conventional thermal cycler has long been a commodity product in the lab and end-point PCR techniques can be completed almost wit...
JUN 09, 2021 7:00 AM PDT
C.E. CREDITS
JUN 09, 2021 7:00 AM PDT
Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
APR 01, 2021 8:00 AM PDT
C.E. CREDITS
APR 01, 2021 8:00 AM PDT
Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
MAR 18, 2021 8:00 AM PDT
C.E. CREDITS
MAR 18, 2021 8:00 AM PDT
DATE: March 18, 2021 TIME: 8:00am PDT Sequencing of bulk cells, single cells, and nuclei is opening doors in the understanding of complex biological processes....
MAR 16, 2021 10:00 AM PDT
C.E. CREDITS
MAR 16, 2021 10:00 AM PDT
Date: March 16, 2021 Time: 10:00am (PST) Scientific progress and breakthroughs today are often too expensive for most institutions to acquire. Each year, the National Institutes of Health (N...
NOV 11, 2015 6:00 AM PST

Clinical next-generation sequencing for precision cancer therapeutics


Specialty

Bioinformatics

Cancer Research

Gene Expression

Dna

Big Data

Cancer Diagnostics

Tumor

Antibodies

Cancer

Research

Oncology

Gene Sequencing

Drug Discovery

Mass Cytometry

Cell Culture

Geography

Asia33%

Europe33%

Africa33%

Registration Source

Website Visitors100%

Job Title

Student33%

Educator/Faculty33%

Medical Laboratory Technician33%

Organization

Academic Institution67%

Manufacturer - Other33%


Show Resources
Loading Comments...
Show Resources