OCT 01, 2015 08:00 AM PDT

WEBINAR: Close your uncertainty gap with High Resolution Mass Spectrometry

Speakers
  • HRAM Product Marketing Manager, Thermo Fisher Scientific
    Biography
      Maciej Bromirski, HRAM Product Marketing Manager at Thermo Fisher Scientific, received his M.Sc. in Physics from the University of Manitoba, Canada followed by a business degree at Georgetown University, USA. Maciej started his career at MassTech, Inc. as a research scientist working on novel TOF instrumentation. He then moved to Europe to work for Waters as a Product Support Specialist. Upon his return to the USA, Maciej rejoined MassTech and in five years progressively moved to become the Director of Business Development for all AP/MALDI ion sources. Since mid 2010, Maciej drives the development and global marketing of the Q Exactive portfolio product out of Bremen, Germany.
    • Strategic Marketing Applications Specialist, Thermo Fisher Scientific
      Biography
        Kristine Van Natta is a Strategic Marketing Applications Specialist with Thermo Fisher Scientific, working on clinical and toxicological applications for mass spectrometry. She received her bachelor's degree in chemistry from the University of California at San Diego in 1988 and a California single subject teaching credential in chemistry in1992.

        Ms. Van Natta has been working in the analytical chemistry field for over 17 years. Her experience includes extensive method development and work performed under both EPA and FDA GLPs. Prior to joining Thermo Fisher Scientific, she worked for Roche Pharmaceuticals in Palo Alto, CA where she developed and validated GLP-compliant methods on LC-MS/MS systems.

        Her responsibilities include applications development and customer training. Her areas of expertise are focused on LC/MS using triple quadrupole and orbitrap mass spectrometers as applied to pharmaceutical research, clinical, and forensic toxicology, most recently concentrating on designer drugs, SAMHSA and pain management.

        Kristine has been a member of the American Chemical Society, the American Association of Pharmaceutical Sciences, Society of Quality Assurance, and California Analytical Chemists Organization.

      Abstract:

      Is your lab constantly challenged by case back log while trying to validate new methods to identify designer drugs? Your challenge is common to many forensic toxicology labs around the world.  To manage challenges, forensic labs deploy a variety of analytical tools, and techniques, such as immunoassay, GC-MS and LC-MS, to arrive at that conclusive result that will hold in the court of law.  This webinar will present a unique LC-MS solution which offers versatile analytical workflows to meet forensic laboratory requirements for screening, quantitation, unknown identification and bulk substance analysis all in one platform. The presented solution utilizes the Thermo Scientific™ Q Exactive™ Focus quadrupole-Orbitrap mass spectrometer to collect highly specific data allowing confident identification and quantitation of compounds. Targeted and universal screening workflows with retrospective data analysis capabilities will be discussed along with confirmatory quantitative methods utilizing parallel reaction monitoring experiment (PRM). Examples of unknown structure identification of a real-case designer drug and bulk substance analysis with a DART source will also be presented.

      Who Should Attend:

      Researchers, Directors, Scientists in the Life Sciences/Forensic Institutes/Health Care/Doping Labs/, Core Facility Personnel interested in learning:

      •    Validated drugs of abuse analysis workflow
      •    Routine toxicology studies involving various designer drugs
      •    Getting rid of the sample backlog situation
      •    Obtaining fully defendable data in less time

      What you will learn:

      •    Effective and efficient workflow for forensic toxicology analysis
      •    Screening, quantitation and confirmation of drugs of abuse compounds
      •    Targeted and unknown screening tools and methods
      •    Unknown structure identification using new LC-MS techniques
      •    Full scan confirmation and parallel reaction monitoring for quantitative results

      For forensic use only.


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