FEB 08, 2018 6:00 AM PST

Comparison of the Impact of Phlebotomy Method on Physiologic and Behavioral Metrics of Pain and Distress in Mice

Speaker
  • Ph.D. Candidate, Weiss Laboratory, Cornell University College of Veterinary Medicine
    Biography
      Elizabeth graduated with a B.S. in Biotechnology from the University of Kentucky in 2008. She then completed a DVM at Cornell University in 2012 and is currently a veterinary resident in laboratory animal medicine with the Cornell Center for Animal Resources and Education. She is concurrently pursuing a PhD in Comparative Biomedical Sciences.

    Abstract

    Nonterminal blood collection from mice is frequently performed in biomedical research. Multiple phlebotomy sites and restraint techniques are available to investigators. Methods that minimize pain and distress in mice can improve the accuracy and reproducibility of research data as well as improve animal welfare. Collection site can influence physiologic parameters, and phlebotomy techniques vary in feasibility and the amount of training required. The methods used to compare the impact of various phlebotomy techniques on animal welfare and data quality vary, making it difficult to compare between studies. Additionally, recommendations proposed by individual studies, institutions, and working groups vary. At Cornell, we recently compared phlebotomy via tail tip amputation to the more commonly used techniques of facial vein puncture and tail vein incision to guide our institutional policies (Moore, ES et al., JAALAS. 2017;56(3)). In this presentation, I will provide an overview of recent publications, including a review of our study, evaluating the impact of rodent phlebotomy technique on parameters of pain and distress.


    Show Resources
    You May Also Like
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    APR 07, 2020 8:00 AM PDT
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    JUN 09, 2020 10:00 AM PDT
    C.E. CREDITS
    JUN 09, 2020 10:00 AM PDT
    DATE: June 9, 2020 TIME: 10:00am PT, 1:00pm ET The presentation will first discuss sepsis as a disease and then explain the importance of performing diagnostic tests in the clinical labora...
    MAY 08, 2020 10:00 AM PDT
    C.E. CREDITS
    MAY 08, 2020 10:00 AM PDT
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    APR 27, 2020 9:00 AM PDT
    C.E. CREDITS
    APR 27, 2020 9:00 AM PDT
    DATE: April 27, 2020 TIME: 9:00am PT, 12:00pm ET Recombinant adeno-associated virus (rAAV) is a small (25-nm) virus that is composed of a protein shell called a capsid and a single-stranded...
    OCT 08, 2020 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    OCT 08, 2020 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: October 8, 2020 TIME: 7:00am PDT, 10:00am EDT, 4:00pm CEST How often do you pipette in your cell culture lab every day? Usually, we do it so often that we tend stop thinking about ho...
    Loading Comments...
    Show Resources
    Attendees
    • See more