AUG 21, 2013 2:00 PM PDT

Comprehensive Chromosome Screening in the Human Embryo

C.E. Credits: CE
Speaker
  • Director of Molecular BiologyResearch, Reproductive Medicine Associatesof New Jersey, Associate Professor, Department of Obstetrics, Gynecology,and Reproductive Sciences, UMDNJ-Robert Wood Jo
    Biography
      Dr. Nathan Treff serves as Director of Molecular Biology Research at RMA of New Jersey, Associate Professor at the Robert Wood Johnson Medical School, and Adjunct Professor at Rutgers University. Dr. Treff's laboratory uses molecular genetics to discover, develop, and translate novel molecular diagnostics to improve the quality of life for patients with infertility and has published more on the use of arrays in preimplantation aneuploidy screening than any other group in the world. His research was awarded the 2007 and 2010 General Program Prize and the 2009 and 2010 Society for Assisted Reproductive Technology Prize by the American Society for Reproductive Medicine. He completed his Ph.D. in biochemistry at Washington State University where he earned the Charles Glenn King Scholarship and the National Institutes of Health Predoctoral Fellowship in protein biotechnology. Dr. Treff trained as a postdoctoral fellow in stem cell biology at the University of Wisconsin-Madison, and in reproductive biology at the EMD-Serono Research Institute.

    Abstract

    The human species is particularly prone to chromosome segregation errors during maternal meiosis in the egg and during post zygotic mitosis in the preimplantation embryo. In fact, aneuploidy represents the most common genetic abnormality in humans, and is the primary cause of infertility, affecting 1 in 6 couples. Despite the extremely limited amount of DNA available from a human embryo, development of genetic technologies, such as qPCR and next generation sequencing, now allow accurate and effective analysis of the copy number of all 24 chromosomes in preimplantation stage human embryos produced during in vitro fertilization (IVF). Selection of chromosomally normal embryos improves the efficacy of single embryo transfer, eliminating the primary complication of IVF (multiple gestations), and improves the success of treating infertility. This presentation will detail the development, validation, and future directions of new human embryo comprehensive chromosome screening technologies.


    Show Resources
    You May Also Like
    APR 07, 2020 8:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    APR 07, 2020 8:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: April 7, 2020 TIME: 8:00am PT, 11:00am ET This webinar sets out to establish why quality control is key to robust, reliable, reproducible science. We will look at best practice criteri...
    OCT 02, 2019 11:00 AM PDT
    OCT 02, 2019 11:00 AM PDT
    DATE: October 2, 2019TIME: 11:00am PDT, 2:00pm EDT Ditch the Excel spreadsheets and manage your molecular workflows entirely in your LIMS Achieve configuration of molecular workf...
    JAN 23, 2020 9:00 AM PST
    C.E. CREDITS
    JAN 23, 2020 9:00 AM PST
    DATE: January 23, 2020 TIME: 9:00am PST, 12:00pm EST...
    MAY 08, 2020 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    MAY 08, 2020 10:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: May 8, 2020 TIME: 10:00am PT, 11:00am MT, 1:00pm ET The application of next generation sequencing to interrogate immune repertoires and methods in which these highly complex dataset...
    FEB 26, 2020 9:00 AM PST
    C.E. CREDITS
    FEB 26, 2020 9:00 AM PST
    DATE: February 26, 2020 TIME: 9:00am PST 3D cell culture and analysis and the study of organoids and spheroids are becoming more prevalent as a research method in publications as traditional...
    FEB 19, 2020 11:00 AM PST
    C.E. CREDITS
    FEB 19, 2020 11:00 AM PST
    DATE: February 19, 2020TIME: 11:00am PST, 2:00pm EST...
    Loading Comments...
    Show Resources
    Attendees