MENU
JAN 31, 2018 8:00 AM PST

High Content Screening-Based Phenotypic Analysis Of Organotypic 3D Bronchial Tissues

Sponsored by: Thermo Fisher Scientific
Speaker
  • High Content Screening Manager, System Toxicology , Philip Morris International R&D
    Biography
      Diego Marescotti is the High Content Screening Manager in the System Toxicology department of Philip Morris International R&D. After completing his PhD in Oncology and Molecular Pharmacology, at the University of Ferrara (Italy) he continued his research investigating the mechanism of tumor escape from immune surveillance. As a scientist he joined Philip Morris International in 2012 bringing his knowledge and interest for flow cytometry and imaging. He is now leading a team of researchers which operate a high-throughput system for compound profiling.

    Abstract

    One of the goals of the “3Rs principle” is to replace in vivo testing methodologies with in vitro procedures on human cells, followed by computational systems biology modelling to determine toxicological risk. System toxicology, which integrates standard toxicology together with quantitative analysis of large networks of molecular and functional changes, have demonstrated the potential to help realize the 3Rs vision. Omics and high content screening methods represent fundamental pillars of a system toxicology-based approach and at Philip Morris International R&D we have developed a large battery of HCS assays to investigate how specific substances alter the phenotype of a cell grown in submerged conditions. As more physiological cell culture model, such as organotypic 3D culture are also part of our portfolio, we invested in the development of imaging-based approaches which would enable high-content investigations of 3D bronchial tissues. In this seminar, recently developed approach for phenotypic analysis of organotypic 3D Bronchial Tissues will be presented.


    Show Resources
    You May Also Like
    MAY 11, 2021 10:00 AM PDT
    C.E. CREDITS
    MAY 11, 2021 10:00 AM PDT
    Date: May 11, 2021 Time: 10:00zm PDT Your samples are some of the most valuable assets in the laboratory. After spending countless hours on extraction and preparation, your conclusions could...
    NOV 18, 2020 8:00 AM PST
    C.E. CREDITS
    NOV 18, 2020 8:00 AM PST
    DATE: November 18, 2020 TIME: 08:00am PDT We develop and implement technologies to solve some of the major bottlenecks in biomedical research. In particular, we establish new imaging approac...
    APR 01, 2021 8:00 AM PDT
    C.E. CREDITS
    APR 01, 2021 8:00 AM PDT
    Date: April 01, 2021 Time: 8:00am (PST), 11:00am (EST) Generating therapeutic antibodies is far more challenging than obtaining antibodies that merely recognize their targets. Engineering po...
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    C.E. CREDITS
    JUN 09, 2021 7:00 AM PDT
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    Date: June 9, 2021 Time: 09 June 2021, 7am PDT, 10am EDT, 4pm CEST cells with dramatic implications on the validity of past cell culture related research. The fact that at least 509 cell lin...
    DEC 02, 2020 8:00 AM PST
    C.E. CREDITS
    DEC 02, 2020 8:00 AM PST
    DATE: December 2nd, 2020 TIME: 08:00am PDT, 11:00pm EDT Bioreactors and shakers are used to cultivate microorganisms, plant, insect, and mammalian cells in different volumes. Upscaling of pr...
    JUN 03, 2021 12:00 PM CST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    JUN 03, 2021 12:00 PM CST
    Add to Calendar Select one of the following: iCal Google Calendar Outlook Calendar Yahoo Calendar
    DATE: June 3, 2021 TIME: 12:00pm SGT This webinar is a virtual event that focuses on utilizing the Gibco CTS Rotea System for Cell and Gene Therapy...
    JAN 31, 2018 8:00 AM PST

    High Content Screening-Based Phenotypic Analysis Of Organotypic 3D Bronchial Tissues

    Sponsored by: Thermo Fisher Scientific

    Specialty

    Cell Biology

    Cell Culture

    Cancer Research

    Biotechnology

    Immunology

    Molecular Biology

    Biomarkers

    Assay Development

    Cell Signaling / Transduction

    Drug Discovery

    Biochemistry

    Cancer Diagnostics

    Genetics

    Cancer Therapeutics

    Gene Expression

    Geography

    North America47%

    Europe30%

    Asia11%

    South America3%

    Oceania2%

    Africa2%

    Registration Source

    Website Visitors75%

    Email Promotions14%

    WAVE Newsletter Promotion8%

    Social Media Promotions1%

    Website Banners1%

    Job Title

    Student18%

    Scientist18%

    Research Scientist14%

    Executive9%

    Facility/Department Manager8%

    Medical Laboratory Technician8%

    Post Doc6%

    Educator/Faculty5%

    Lab Management4%

    Biologist3%

    Medical Doctor/Specialist3%

    Clinical Laboratory Scientist2%

    Marketing/Sales1%

    Organization

    Academic Institution13%

    Biotech Company10%

    Research Institute9%

    Life Science Company7%

    Clinical Laboratory6%

    Hospital4%

    Pharmaceutical Company4%

    Ambulatory Care4%

    Industrial Company3%

    Medical Center2%

    Government2%

    Medical Device Company1%

    Non-Profit Organization1%

    Consultant1%

    Other6%


    Show Resources
    Loading Comments...
    Show Resources
    Attendees
    • See more