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Contribution of transposons to structural variation and phenotypic diversity in tomato

C.E. Credits: P.A.C.E. CE Florida CE
Speaker
  • Research Associate, Lippman Lab, Howard Hughes Medical Institute, Cold Spring Harbor Laboratory
    Biography
      Matthias is an HHMI post-doctoral fellow working in Zach Lippman's group at Cold Spring Harbor Laboratory (New York, USA). He completed a PhD in Molecular Genetics and Physiology with Aline V. Probst at Clermont Auvergne University (France), where he studied histone variants and chromatin dynamics during early seedling development in Arabidopsis. He then joined Jurek Paszowski's group at the Sainsbury Laboratory (University of Cambridge, UK) to characterize transposons subjected to developmental and environmental activation in tomato. Matthias' current and future research aim at understanding the significance of genomic and epigenetic variation in tomato development and breeding.

    Abstract

    Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural variation at the population level has remained challenging. I will discuss how we revealed the extent and the genomic features of structural variants in 100 tomato accessions using long-read sequencing. I will show that transposons underlie a large fraction of structural variants. In a second part, I will provide a characterization of a transposon family that has driven structural variation and has facilitated the emergence of phenotypic variation in tomato.

    Learning Objectives:
    1. Dissection of the structural variation landscape in the tomato genome

    2. Characterization of a transposon family involved in structural variation in the tomato genome


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