Chromatin Dynamics
Chromatin Dynamics refers to the movements and interactions in the nucleus which plays a crucial role in gene regulation. The dynamic structure of chromatin modulates other nuclear processes, including transcription and replication, by altering the accessibility of the DNA to regulatory factors.
What's Popular in Chromatin Dynamics
Structural variation within plant genomes has fueled domestication and selection of traits critical for modern breeding of crop plants. Nevertheless, dissecting the diversity of structural v...
MAY 08, 2019
6:00 AM PDT
C.E. CREDITS
MAY 08, 2019
6:00 AM PDT
Genetic drivers of cancer can be dysregulated through epigenetic modifications of DNA. Although the critical role of DNA 5-methylcytosine (5mC) in the regulation of transcription is recognize...
JUN 20, 2018
6:00 AM PDT
JUN 20, 2018
6:00 AM PDT
Precision medicine and next-generation sequencing – Two terms characterized by a highly dynamic nature, strong innovations and a bright future. Both merged together will exert a decisiv...
OCT 12, 2017
1:30 PM PDT
OCT 12, 2017
1:30 PM PDT
The deposition and removal of DNA and histone modifications depends on the availability of specific metabolites, suggesting that cellular metabolic pathways may dynamically regulate chromatin...
OCT 12, 2017
6:00 AM PDT
OCT 12, 2017
6:00 AM PDT
We developed two computational methods, CARE and TIDE, to predict response and resistance to targeted therapies and immunotherapies. CARE infers gene signatures of targeted therapy response b...
SEP 19, 2017
10:30 AM PDT
SEP 19, 2017
10:30 AM PDT
DATE: September 19, 2017TIME: 10:30am PDT/ 1:30pm EDT/ 7:30pm CESTPart 1 – Cigall Kadoch, Ph.D. (30 min.)Exome- and genome-wide sequencing studies in human cancer have...
