FEB 20, 2017 8:00 AM PST

Critical Analysis of Biosensor Data Sets - making sure your conclusions and values are believable

Speaker

Abstract

Biosensors are now a well-established technology in the study of small molecules.  This talk will focus on several aspects of this type of work that biosensor users can be expected to explain.  These are: A) Describing Mass Transport: Mass transport is a common phenomenon in biosensor data that can affect the uniqueness of solutions derived from fits.  The origins of mass transport will be described as well as how mass transport has been modeled quantitatively to help explain the lack of uniqueness in solutions.   How mass transport manifests itself with respect to the shape of sensorgrams will also be described. B)  Reproducibility of Biosensor Data: Biosensors are commonly used to derive rate and equilibrium constants for molecular interactions.  Many of these values appear in publications and technical reports.  A commonly asked question about this technology relates to the magnitude of experimental errors that can typically be expected.  Some case examples will be discussed to help orient the audience as to the reliability of values of cited. C) Problematic Data:   Several case examples of actual problematic data that has been collected will be presented.  The dilemma that some of these data sets can pose in their interpretation will be discussed.


Show Resources
You May Also Like
JUN 28, 2022 7:00 AM PDT
JUN 28, 2022 7:00 AM PDT
Date: June 28, 2022 Time: 3:00pm (BST), 4:00pm (CET), 9:00am (CST), 7am (PST) Light-sheet microscopy is an extremely versatile imaging technique with a vast range of implementations that are...
OCT 11, 2022 8:00 AM PDT
C.E. CREDITS
OCT 11, 2022 8:00 AM PDT
Date: October 11, 2022 Time: 8:00am (PDT), 11:00pm (EDT), 5:00pm (CEST) Multiomic profiling of cell populations at single-cell resolution is revolutionizing scientists’ understanding o...
MAY 17, 2022 9:00 AM PDT
MAY 17, 2022 9:00 AM PDT
Date: May 17, 2022 Time: 9:00am (PDT), 12:00pm (EDT), 8:00pm (CEST) Gene therapeutics have great potential to treat many severe diseases in an unprecedented, targeted manner. The biopharmace...
JUN 22, 2022 10:00 AM PDT
JUN 22, 2022 10:00 AM PDT
Date: June 22, 2022 Time: 10:00am (PDT), 1:00pm (EDT), 7:00pm (CEST) Rabbits have a robust and unique immune system that enables the generated antibodies with superior specificity, affinity,...
MAR 02, 2022 9:00 AM PST
C.E. CREDITS
MAR 02, 2022 9:00 AM PST
Date: March 02, 2022 Time: 9:00am (PST), 12:00pm (EST) Single cell RNA-seq is known to only capture a small fraction of the transcriptome of each cell. Often, this is due to inherent limitat...
SEP 13, 2022 8:00 AM PDT
SEP 13, 2022 8:00 AM PDT
Date: September 13, 2022 Time: 8:00am (PDT), 11:00am (EDT), 5:00pm (CEST) Preparedness against pandemic diseases demands rapid-response vaccine technology and ready-to-use analytical methods...
FEB 20, 2017 8:00 AM PST

Critical Analysis of Biosensor Data Sets - making sure your conclusions and values are believable



Show Resources
Loading Comments...
Show Resources